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Congenital Hypoplastic Anemia

Subscribe to New Research on Congenital Hypoplastic Anemia

An inborn condition characterized by deficiencies of red cell precursors that sometimes also includes LEUKOPENIA and THROMBOCYTOPENIA.

Also Known As:

Anemia, Hypoplastic, Congenital; Anemia, Congenital Hypoplastic; Anemias, Congenital Hypoplastic; Congenital Hypoplastic Anemias; Hypoplastic Anemias, Congenital; Hypoplastic Anemia, Congenital

Networked: 42 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan)
2.	Aplastic Anemia (Anemia, Hypoplastic)
3.	Anemia
4.	Fanconi Anemia (Fanconi's Anemia)
5.	Polymyositis

Experts

1.	Tchernia, Gil: 2 articles (12/2004 - 06/2003)
2.	Głąb, Ewa: 1 article (01/2013)
3.	Barg, Ewa: 1 article (01/2013)
4.	Wikiera, Beata: 1 article (01/2013)
5.	Bieniasz, Jolanta: 1 article (01/2013)
6.	Flygare, Johan: 1 article (11/2008)
7.	Karlsson, Stefan: 1 article (11/2008)
8.	Richter, Johan: 1 article (11/2008)
9.	Olsson, Karin: 1 article (11/2008)
10.	Zeidler, C: 1 article (12/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Congenital Hypoplastic Anemia:

1.	Adrenal Cortex Hormones (Corticosteroids)IBA 08/01/1990 - "In patients with congenital hypoplastic anemia the best results have been reported using corticosteroids. " 08/01/1984 - "Allogeneic bone marrow transplantation (BMT) was carried out on a 5-year-old boy with congenital hypoplastic anemia (CHA), who did not respond to corticosteroids and who was displaying signs of progressive hemosiderosis. "
2.	DiamondIBA 01/01/1986 - "[Studies on the pathogenesis of congenital hypoplastic anemia (Diamond-Blackfan syndrome)]." 01/01/2013 - "Congenital hypoplastic anemia (Diamond-Blakcfan syndrom) is a genetically determined disorder which is manifested in early childhood with selective deficiency of erythrocyte line in bone marrow. " 12/01/1991 - "Congenital hypoplastic anemia (CHA; syn: Diamond-Blackfan syndrome) is a rare disorder with one of two patients a year in the Netherlands. " 03/01/1985 - "The CM-S cell line was established from the bone marrow of a patient suffering from congenital hypoplastic anemia (syndrome of Diamond-Blackfan). " 09/01/1982 - "Congenital hypoplastic anemia (Diamond-Blackfan syndrome) is thought to involve the erythropoietic cell line alone. "
3.	Erythropoietin FDA Link 01/01/1991 - "Treatment trial with recombinant human erythropoietin in children with congenital hypoplastic anemia."
4.	Tryptophan (L-Tryptophan)FDA Link 04/01/1954 - "DEFECT in tryptophan metabolism in congenital hypoplastic anemia." 02/01/1970 - "Excretion of urinary tryptophan metabolites by patients with congenital hypoplastic anemia (Diamond-Blackfan syndrome)." 08/25/1960 - "[On the spontaneous urinary excretion of metabolites of the tryptophan-nicotinic acid interaction of 2 infant brothers with the Fanconi type of congenital hypoplastic anemia]."
5.	Ribosomal Proteins (Ribosomal Protein)IBA 11/01/2008 - "Diamond-Blackfan anemia (DBA) is a rare congenital hypoplastic anemia caused by mutations in ribosomal protein (RP) genes. " 12/01/2004 - "Mutations in the ribosomal protein (RP)S19 gene have been found in about 25% of the cases of Diamond-Blackfan anemia (DBA), a rare congenital hypoplastic anemia that includes variable physical malformations. "
6.	Deferoxamine (Desferal)FDA LinkGeneric 09/01/1988 - "[Effect of continuous subcutaneous infusion of deferoxamine in a boy with congenital hypoplastic anemia]." 01/01/1982 - "Effect of subcutaneous deferoxamine and oral vitamin C on iron excretion in congenital hypoplastic anemia and refractory anemia associated with the 5q-syndrome."
7.	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 03/01/1985 - "Eight patients with severe aplastic anemia (SAA) and two patients with congenital hypoplastic anemia (CHA) were treated with absorbed samples of rabbit anti-thymocyte globulin (ATG) at a total dose of 50-75 mg/kg body weight intravenously over 5 days. " 01/01/1985 - "Forty-six patients with severe aplastic anemia (SAA), 1 with adult pure red cell aplasia (PRCA), 1 with congenital hypoplastic anemia (Diamond-Blackfan) and 1 with severe polymyositis were treated with intravenous antilymphocyte globulins (ALG) of different sources (2 of equine and 1 of rabbit origin). "
8.	Prednisone (Sone)FDA LinkGeneric 01/01/1970 - "Treatment of congenital hypoplastic anemia with prednisone."
9.	Niacin (Nicotinic Acid)FDA LinkGeneric 08/25/1960 - "[On the spontaneous urinary excretion of metabolites of the tryptophan-nicotinic acid interaction of 2 infant brothers with the Fanconi type of congenital hypoplastic anemia]."
10.	IronIBA 01/01/1982 - "C) on urinary iron excretion was studied in two patients with congenital hypoplastic anemia and one patient with 5q-syndrome. " 01/01/1982 - "Effect of subcutaneous deferoxamine and oral vitamin C on iron excretion in congenital hypoplastic anemia and refractory anemia associated with the 5q-syndrome."

Therapies and Procedures

1.	Bone Marrow Transplantation (Transplantation, Bone Marrow) 04/01/1977 - "Bone marrow transplantation in congenital hypoplastic anemia." 10/01/1976 - "Establishment of erythropoiesis following bone marrow transplantation in a patient with congenital hypoplastic anemia (Diamond-Blackfan syndrome)." 08/01/1984 - "Allogeneic bone marrow transplantation (BMT) was carried out on a 5-year-old boy with congenital hypoplastic anemia (CHA), who did not respond to corticosteroids and who was displaying signs of progressive hemosiderosis. "
2.	Subcutaneous Infusions 09/01/1988 - "[Effect of continuous subcutaneous infusion of deferoxamine in a boy with congenital hypoplastic anemia]."
3.	Transplants (Transplant) 08/01/1984 - "Complete recovery of hemopoiesis following bone marrow transplant in a patient with unresponsive congenital hypoplastic anemia (Blackfan-Diamond syndrome)."
4.	Transplantation (Transplant Recipients) 10/01/1976 - "Marrow transplantation was attempted in a 13-yr-old boy with congenital hypoplastic anemia who had never responded to corticosteroid therapy. "