Peste-des-Petits-Ruminants

A highly fatal contagious disease of goats and sheep caused by PESTE-DES-PETITS-RUMINANTS VIRUS. The disease may be acute or subacute and is characterized by stomatitis, conjunctivitis, diarrhea, and pneumonia.

Also Known As:

Networked: 70 relevant articles (5 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	African Horse Sickness (African Horsesickness)
2.	Paramyxoviridae Infections (Parainfluenza)
3.	Rinderpest (Cattle Plague)
4.	Measles
5.	Rift Valley Fever

Experts

1.	Bandyopadhyay, S K: 7 articles (11/2006 - 01/2004)
2.	Singh, R P: 6 articles (04/2006 - 01/2004)
3.	Singh, R K: 5 articles (07/2010 - 07/2005)
4.	Dhar, P: 5 articles (11/2006 - 01/2004)
5.	Sreenivasa, B P: 5 articles (04/2006 - 01/2004)
6.	Kwiatek, Olivier: 3 articles (06/2014 - 12/2008)
7.	Balamurugan, V: 3 articles (07/2010 - 11/2006)
8.	Nachimuthu, K: 3 articles (07/2010 - 09/2000)
9.	Couacy-Hymann, E: 3 articles (10/2009 - 07/2006)
10.	Boshra, Hani: 2 articles (01/2015 - 05/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Peste-des-Petits-Ruminants:

1.	VaccinesIBA 06/24/2014 - "Protective efficacy of a single immunization with capripoxvirus-vectored recombinant peste des petits ruminants vaccines in presence of pre-existing immunity." 10/01/2011 - "Evaluation of efficacy of stabilizers on the thermostability of live attenuated thermo-adapted Peste des petits ruminants vaccines." 07/01/2010 - "Comparative efficacy of peste des petits ruminants (PPR) vaccines." 12/01/2014 - "Current perspectives on conventional and novel vaccines against peste des petits ruminants." 01/01/2003 - "Control of peste des petits ruminants: classical and new generation vaccines."
2.	AntibodiesIBA 04/01/2006 - "Comparison of diagnostic efficacy of a monoclonal antibody-based competitive ELISA test with a similar commercial test for the detection of antibodies to Peste des Petits Ruminants (PPR) virus." 07/17/2006 - "This study highlights the interference by peste des petits ruminants vaccination, presumably through production of antibodies that cross react with the live rinderpest virus in the vaccine used. " 04/01/2009 - "Serum samples were collected from all the animals and tested for the presence of antibodies against Peste des petits ruminants (PPR) virus using competitive ELISA (cELISA). " 04/01/2009 - "Post-vaccination antibodies profile against Peste des petits ruminants (PPR) virus in sheep and goats of Punjab, Pakistan." 12/01/2008 - "This paper presents the results of a seroepidemiological study carried out between July 2006 and March 2007 to detect the presence of antibodies to peste des petits ruminants (PPR) virus in randomly collected serum samples from sheep and goats in southern peninsular India. "
3.	Monoclonal AntibodiesIBA 03/01/2009 - "Comparative efficacy of standard AGID and precipitinogen inhibition test with monoclonal antibodies based competitive ELISA for the serology of Peste des Petits Ruminants in sheep and goats." 10/01/2004 - "Production and characterization of monoclonal antibodies to peste des petits ruminants (PPR) virus." 11/07/1987 - "A morbillivirus was isolated and using monoclonal antibodies and biological tests in cattle, sheep and goats the virus of peste des petits ruminants was identified." 02/15/1991 - "Monoclonal antibodies (MAb) raised against the RBOK vaccine strain of rinderpest virus were characterized by radio-immunoprecipitation (RIPA) and in the indirect ELISA using measles (MV), distemper (CDV), rinderpest (RPV) and peste des petits ruminants viruses (PPRV). " 10/01/1990 - "Comparison of rinderpest and peste des petits ruminants viruses using anti-nucleoprotein monoclonal antibodies."
4.	AntigensIBA 10/01/2009 - "The early detection of peste-des-petits-ruminants (PPR) virus antigens and nucleic acid from experimentally infected goats using RT-PCR and immunocapture ELISA techniques." 01/01/2004 - "The production and evaluation of a standard reference peste des petits ruminants (PPR)-diagnostic antigen using a sonication technique." 01/01/2004 - "The production and evaluation of a standard diagnostic peste des petits ruminants (PPR) hyperimmune serum prepared from the Egyptian antigen (Egypt 87)." 01/16/1998 - "Several of these sera were also positive when tested against peste des petits ruminants and rinderpest virus antigen. " 01/01/1994 - "rRVN was used as a coating antigen in an ELISA to distinguish vaccinated animals from those infected with RPV and was also used successfully in the diagnosis of two other morbilliviruses, MV and peste des petits ruminants (PPRV). "
5.	DNA (Deoxyribonucleic Acid)IBA 12/01/2007 - "Two animal viruses, African swine fever, a large double-stranded DNA virus and Peste des Petits Ruminants, a negative single-stranded RNA virus, were used to validate the method. " 11/01/2009 - "In the present study, TaqMan probe quantitative polymerase chain reaction (QPCR) based on conserved DNA pol gene of capripoxvirus was developed for the quality control of attenuated monovalent goatpox and/or combined attenuated goatpox and peste des petits ruminants (PPR) vaccines. "
6.	Carbon MonoxideIBA 08/01/2012 - "The present study deals with the co-ordination of cytokine (IL-4 and IFN-γ) expression and kinetics of peste des petits ruminants (PPR) virus antigen and antibody in PPRV infected and vaccinated goats. " 02/01/2014 - "Formation of peste des petits ruminants spikeless virus-like particles by co-expression of M and N proteins in insect cells."
7.	AgarIBA 03/01/2009 - "This project was conducted to investigate the comparative efficiency of competitive ELISA (cELISA), standard Agar Gel Immunodiffusion Test (AGID) and Precipitinogen Inhibition Test (PIT) for the diagnosis of Peste des Petits Ruminants (PPR) in Pakistan. " 06/01/2008 - "Rapid detection of Peste des Petits Ruminants (PPR) virus antigen in Sudan by agar gel precipitation (AGPT) and haemagglutination (HA) tests." 12/01/1984 - "The detectability of peste des petits ruminants (PPR) viral antigen in both ante-mortem secretions and necropsy samples from experimentally infected goats was investigated by both the agar gel precipitation test (AGPT) and counter-immunoelectrophoresis (CIE). " 12/01/1984 - "The detection of peste des petits ruminants (PPR) virus antigen by agar gel precipitation test and counter-immunoelectrophoresis." 10/01/2001 - "This paper is based on observations on the performance of the antigen detection ELISA compared to the agar gel immunodiffusion (AGID) test, which also differentiates rinderpest from peste des petits ruminants (PPR). "
8.	Complementary DNA (cDNA)IBA 01/01/2012 - "The full-length gene encoding the nucleocapsid (N) protein of the virus (PPRV) responsible for an outbreak of peste des petits ruminants in Tibet in 2007 was synthesized in two stages using overlapping PCR without the need for viral genomic cDNA as template. " 02/01/1989 - "Differentiation of rinderpest and peste des petits ruminants viruses using specific cDNA clones." 05/01/1994 - "An outbreak of disease characterised by fever, ocular and nasal discharge, coughing and sneezing, oral necrosis, diarrhoea, enteritis and pneumonia in goats was shown by the use of specific cDNA probes to have been peste des petits ruminants, confirmed for the first time in Ethiopia. "
9.	RNA (Ribonucleic Acid)IBA 01/01/2013 - "Peste des petits ruminants virus (PPRV); a negative sense single stranded RNA enveloped virus that causes Peste des petits ruminants (PPR), is dramatically affecting the health status of ruminants all around the world resulting in extensive economical losses in livestock sector. " 06/01/2001 - "Oculonasal swabs and tissue samples collected from peste des petits ruminants (PPR) suspected sheep and goats were tested for presence of the virus of peste des petits ruminants (PPRV) or its RNA by reverse transcription-PCR (RT-PCR) and virus isolation (VI). " 06/01/1990 - "RNA purified from post-mortem tissues removed from diseased seals has been analysed by hybridisation with cloned cDNAs made to various genes of canine distemper, peste des petits ruminants, rinderpest and measles viruses. "
10.	NucleoproteinsIBA 11/01/2006 - "Sequence analysis of the nucleoprotein gene of Asian lineage peste des petits ruminants vaccine virus." 01/01/1994 - "Comparisons of the nucleic acid and protein sequences of all the morbillivirus nucleoproteins so far determined indicated two major subgroups in the morbillivirus genus of the Paramyxoviridae: one group included canine and phocine distemper viruses, and the other rinderpest, measles and peste-des-petits-ruminants viruses. " 10/01/1990 - "Comparison of rinderpest and peste des petits ruminants viruses using anti-nucleoprotein monoclonal antibodies."