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Fusion Regulatory Protein-1

A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.
Also Known As:
4F2 Antigen; 4F2-antigen; CD98 Antigen; CD98 Transport Proteins; FRP-1 protein; H4F2 Antigen; Human 4F2 Antigen; Human 4F2 Cell-Surface Antigen; Human Lymphocyte Activation Antigen 4F2; 4F2 Antigen, Human; Antigen, CD98; FRP 1 protein; Fusion Regulatory Protein 1; Human 4F2 Cell Surface Antigen; Regulatory Protein-1, Fusion; Transport Proteins, CD98; Antigen 4F2; Antigens, CD98; CD98 Antigens
Networked: 21 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ando, Keisuke: 1 article (01/2021)
2. Anzai, Naohiko: 1 article (01/2021)
3. Fujimoto, Ayumi: 1 article (01/2021)
4. Ichikawa, Tomohiko: 1 article (01/2021)
5. Ikeda, Jun-Ichiro: 1 article (01/2021)
6. Ikehara, Yuzuru: 1 article (01/2021)
7. Imamura, Yusuke: 1 article (01/2021)
8. Kanai, Yoshikatsu: 1 article (01/2021)
9. Kaneda, Atsushi: 1 article (01/2021)
10. Kanesaka, Manato: 1 article (01/2021)

Related Diseases

1. Neoplasms (Cancer)
2. Medullary Carcinoma
3. Crohn Disease (Crohn's Disease)
4. Carcinoma (Carcinomatosis)
5. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)

Related Drugs and Biologics

1. Antigens
2. Transferrin Receptors (Transferrin Receptor)
3. Interleukin-2 Receptors (IL 2 Receptor)
4. Proteins (Proteins, Gene)
5. Monoclonal Antibodies
6. DNA (Deoxyribonucleic Acid)
7. Amino Acid Transport Systems (Amino Acid Transporter)
8. Integrins
9. CD Antigens
10. Tyrosine (L-Tyrosine)