A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.
Also Known As:
Topoisomerase IV; Topo IV; Topoisomerase IV Subunit A; Topoisomerase IV Subunit B; parC Gene Product; parC Gene Product, Topo IV; parE Gene Product; parE Gene Product, Topo IV; Topoisomerase IV, DNA; parC Protein; parE Protein