Ecdysteroids

Steroids that bring about MOLTING or ecdysis in insects. Ecdysteroids include the endogenous insect hormones (ECDYSONE and ECDYSTERONE) and the insect-molting hormones found in plants, the phytoecdysteroids. Phytoecdysteroids are natural insecticides.

Also Known As:

Networked: 92 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hunyadi, Attila: 8 articles (01/2020 - 06/2012)
2.	Martins, Ana: 6 articles (01/2018 - 06/2012)
3.	Mykles, Donald L: 5 articles (01/2019 - 01/2003)
4.	Tóth, Gábor: 4 articles (01/2020 - 12/2013)
5.	Csábi, József: 4 articles (01/2017 - 12/2013)
6.	Chang, Ernest S: 4 articles (01/2016 - 01/2003)
7.	Vágvölgyi, Máté: 3 articles (01/2020 - 01/2018)
8.	Zupkó, István: 3 articles (01/2020 - 06/2012)
9.	Abuhagr, Ali M: 3 articles (01/2016 - 02/2012)
10.	Gáti, Tamás: 2 articles (01/2020 - 01/2018)

Related Diseases

1.	Neoplasms (Cancer) 01/25/2017 - "Our previous studies showed certain ecdysteroid derivatives as promising chemo-sensitizers against MDR and non-MDR cancer cell lines while also exerting mild to moderate inhibition of P-gp function. " 01/20/2018 - "We had previously described the chemo-sensitizing activity of ecdysteroid derivatives with low polarity on drug susceptible and multi-drug resistant (MDR) cancer cells. " 01/25/2017 - "Our results showed for the first time that the chemo-sensitizing activity of ecdysteroids can be fully independent of functional efflux pump inhibition, and suggest these compounds as favorable leads against MDR cancer." 01/01/2017 - "A comprehensive physicochemical profiling was performed for a set of natural or semi-synthetic ecdysteroids (N=37) to identify a lead compound against central nervous system (CNS) tumors. " 01/01/2017 - "BBB penetration-targeting physicochemical lead selection: Ecdysteroids as chemo-sensitizers against CNS tumors."
2.	Seborrheic Dermatitis 01/01/2020 - "Moreover, this study has shown a positive effect of ecdysteroids-containing cream on changes in quality of life and a beneficial effect in reducing the symptoms of seborrheic dermatitis. "
3.	Infections 01/01/2018 - "Molt status appeared to be influenced by infection, with infected crabs having significantly lower concentrations of ecdysteroids than uninfected crabs in the spring and the fall. " 01/01/2016 - "Our results indicate that the release of ecdysteroids was reduced not by infection of the PGs by MySEV, but by reduced PTTH production from the brain. " 09/15/2009 - "In vitro ecdysteroid assays further indicated that prothoracic glands from larvae infected prior to achieving critical weight remained in a refractory state of ecdysteroid release, whereas infection of post-critical weight larvae had little or no effect on ecdysteroid release by prothoracic glands. " 08/01/2000 - "Thus, EPV infection results in increased JH titer and decreased ecdysteroid titer. " 12/01/1993 - "Important differences of levels of ecdysteroid-like compounds between the two sexes of parasites were noted particularly at 128 and 168 h post-infection. "
4.	Starvation 01/01/2023 - "This work suggests that starvation selection causes reduced and delayed production of ecdysteroids in the larval stage and affects the developmental delay phenotype that contributes to subsequent adult fat storage and starvation resistance." 01/01/2020 - "sexta, starvation consistently reduced transcriptional activation of ecdysteroid biosynthesis genes even after CW attainment, indicating that the nature of CW differs fundamentally between the two species. " 09/01/2006 - "However, when starvation began on day 3 of the last larval instar, the major hemolymph ecdysteroid peak, preceding larval-pupal transformation, occurred 1 day earlier than that in control larvae. " 11/01/2005 - "Altogether, these results suggest that starvation induces a rapid decline in the JH titer, and this cues the early occurrence of a small ecdysteroid peak that commits larvae to early metamorphosis." 10/01/2005 - "Starvation causes the ovary to retain the ecdysteroid it produces, thus enabling individual egg chambers to undergo apoptosis and thus control the number of eggs produced in relation to food intake."
5.	Ganglion Cysts (Ganglion) 11/01/1987 - "Isolation of this ganglion from anterior parts of the nervous system can prevent the death of these cells at the time when they would normally die in response to the decline in ecdysteroids. " 01/01/1987 - "Isolation of this ganglion from the thoracic ganglia can prevent the death of these cells at the time when they would normally die in response to removal of ecdysteroids. " 01/01/1987 - "This suggests that two or more neural factors, at least one from the brain lobes and another from the ventral ganglion, interact to stimulate ecdysteroid synthesis by the larval ring gland." 01/01/1987 - "However, while extract prepared from larval brains elicits only a slight increase in ecdysteroid synthesis, it enhances the activity of a submaximal dose of ventral ganglion extract. " 03/01/1986 - "Removal of the brain from a CNS isolated prior to ecdysteroid exposure resulted in the appearance of spontaneous bursts, which were abolished by removing the suboesophageal ganglion (SEG). "

Related Drugs and Biologics

1.	Hormones (Hormone)
2.	Ecdysone
3.	Proteins (Proteins, Gene)
4.	Ecdysteroids
5.	Doxorubicin (Adriamycin)
6.	Juvenile Hormones
7.	Ecdysterone (20 Hydroxyecdysone)
8.	Vincristine (Oncovin)
9.	Serotonin (5 Hydroxytryptamine)
10.	Lipids

Related Therapies and Procedures

1.	Injections