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Phosphofructokinase-2 (Phosphofructokinase 2)

An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.
Also Known As:
Phosphofructokinase 2; 6-PF-2-K-Fru-2,6-P(2)ase; 6-Phosphofructo 2-kinase-fructose 2,6-bisphosphatase; 6PF2K; ATP-D-Fructose-6-phosphate 2-phosphotransferase; F Kinase-F-bisphosphatase; Fru-6-P,2-kinase; Fru-kinase-Fru-bisphosphatase; Fructose 2,6-bisphosphatase; Fructose-2,6-bisphosphate 2-phosphatase; Fructose-6-P,2-kinase; Fructose-6-phosphate,2-kinase; Fructose-6-phosphate,2-kinase-fructose-2,6-bisphosphatase; fructose-2,6-diphosphatase; 6-Phosphofructo-2-kinase; 6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase; Fructose-2,6-bisphosphatase
Networked: 60 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Li, Honggui: 5 articles (01/2021 - 02/2010)
2. Wu, Chaodong: 5 articles (01/2021 - 02/2010)
3. Chesney, Jason: 5 articles (11/2016 - 01/2008)
4. Telang, Sucheta: 5 articles (11/2016 - 01/2008)
5. Huo, Yuqing: 4 articles (04/2016 - 02/2010)
6. Bartrons, Ramon: 3 articles (01/2018 - 12/2004)
7. Guo, Xin: 3 articles (01/2016 - 02/2010)
8. Trent, John O: 3 articles (07/2015 - 01/2008)
9. Xu, Hang: 2 articles (01/2021 - 06/2012)
10. Manzano, Anna: 2 articles (01/2018 - 01/2008)

Related Diseases

1. Insulin Resistance
2. Inflammation (Inflammations)
3. Sepsis (Septicemia)
4. Squamous Cell Carcinoma of Head and Neck
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Fructose
2. fructose 2,6-diphosphate
3. Phosphotransferases (Kinase)
4. Phosphofructokinase-1 (Phosphofructokinase 1)
5. Glucose (Dextrose)
6. Enzymes
7. Proteins (Proteins, Gene)
8. Phosphofructokinase-2 (Phosphofructokinase 2)
9. AMP-Activated Protein Kinases
10. Protein Isoforms (Isoforms)

Related Therapies and Procedures

1. Electroacupuncture
2. Aftercare (After-Treatment)
3. High-Protein Diet