Streptogramin Group B

A structural subclass of streptogramins. They are cyclic hexadepsipeptides with approximate molecular weight of 800 that contain a characteristic 3-hydroxy picolinoyl exocyclic component.

Also Known As:

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Hung-Mo: 1 article (06/2007)
2.	Huang, Ay-Huey: 1 article (06/2007)
3.	Janapatla, Rajendra Prasad: 1 article (06/2007)
4.	Wu, Hsiu-Mei: 1 article (06/2007)
5.	Wu, Jiunn-Jong: 1 article (06/2007)
6.	Yan, Jing-Jou: 1 article (06/2007)
7.	Giamarellou, Helen: 1 article (02/2006)
8.	Maltezou, Helen C: 1 article (02/2006)
9.	Bruckner, Robert C: 1 article (07/2004)
10.	Jorns, Marilyn Schuman: 1 article (07/2004)

Related Diseases

1.	Soft Tissue Infections 02/01/2006 - "Clindamycin is an effective agent for skin and soft tissue infections, however attention should be paid to the possibility of the emergence of resistance during treatment in strains with the macrolide, lincosamide and group B streptogramin (MLS(B))-inducible resistance phenotype. "
2.	Infections 07/20/2004 - "In addition to nikkomycins, a nikD-like reaction is implicated in the biosynthesis of an L-lysine-derived pyridyl moiety found in streptogramin group B antibiotics that are used as part of a last resort treatment for severe infections due to gram positive bacteria." 06/01/2007 - "A major concern while prescribing clindamycin to treat infections caused by inducible macrolide, lincosamide, and group B streptogramin (iMLS(B))-resistant strains is clinical therapy failure. "

Related Drugs and Biologics

1.	Macrolides
2.	Clindamycin (Cleocin)
3.	Lysine (L-Lysine)
4.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Therapeutics