Sex Chromosome Disorders

Clinical conditions caused by an abnormal sex chromosome constitution (SEX CHROMOSOME ABERRATIONS), in which there is extra or missing sex chromosome material (either a whole chromosome or a chromosome segment).

Also Known As:

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Klinefelter Syndrome (Klinefelter's Syndrome)
2.	Hypogonadism (Hypergonadotropic Hypogonadism)
3.	Azoospermia
4.	Trisomy (Trisomies)
5.	Male Infertility (Male Sterility)

Experts

1.	Bojesen, Anders: 2 articles (03/2014 - 06/2011)
2.	Tartaglia, N: 1 article (02/2015)
3.	Merry, D E: 1 article (02/2015)
4.	Ross, J L: 1 article (02/2015)
5.	Dalva, M: 1 article (02/2015)
6.	Zinn, A R: 1 article (02/2015)
7.	Skakkebæk, Anne: 1 article (03/2014)
8.	Høst, Christian: 1 article (03/2014)
9.	Groth, Kristian A: 1 article (03/2014)
10.	Chen, Shuang: 1 article (02/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Sex Chromosome Disorders:

1.	Complement System Proteins (Complement)IBA 01/01/2008 - "We concluded that PCR as a simple, rapid and reliable technique can complement and also confirm cytogenetic studies in the diagnosis of sex in cases of sex chromosome disorders."
2.	XXY syndromeIBA 09/01/2013 - "Klinefelter syndrome is a common sex chromosome disorder characterized by the presence of 1 or more extra X chromosomes, and the most prevalent karyotype is 47,XXY. " 12/01/2010 - "Klinefelter syndrome (47, XXY male) is the most common sex chromosome disorder in men. " 03/01/2014 - "Klinefelter syndrome (KS) (47, XXY) is the most abundant sex-chromosome disorder, and is a common cause of infertility and hypogonadism in men. " 06/01/2011 - "Klinefelter syndrome (KS) (47,XXY) is the most common sex chromosome disorder in man and is a relatively common cause of male infertility and hypogonadism. " 02/01/2014 - "Y chromosome micro deletions and sex chromosome disorders particularly Klinefelter's (47, XXY), have severe adverse influence on normal hormone levels, testicular volume and sperm count, whereas translocation abnormalities may inversely correlate with sperm motility."
3.	HormonesIBA 02/01/2014 - "Y chromosome micro deletions and sex chromosome disorders particularly Klinefelter's (47, XXY), have severe adverse influence on normal hormone levels, testicular volume and sperm count, whereas translocation abnormalities may inversely correlate with sperm motility." 08/01/2003 - "Klinefelter syndrome is the most common sex chromosome disorder, characterized by 47, XXY karyotype, resulting in male hypogonadism and sex hormone imbalance. "
4.	GonadotropinsIBA 01/01/2014 - "Klinefelter syndrome (KS) is a common sex chromosome disorder and is characterized by small, firm testes with hyalinization of the seminiferous tubules, elevated gonadotropins and azoospermia. "
5.	Patau syndromeIBA 03/01/2006 - "Of fetuses with chromosome aberrations, 144 (69.56%) had trisomy 13, trisomy 18, trisomy 21, or sex chromosome disorder. "
6.	XYY syndrome 47IBA 02/01/2015 - "The male sex chromosome disorder, 47,XYY syndrome (XYY), is associated with increased risk for social-emotional difficulties, attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). "