Second-Look Surgery

04/01/1997 - "For those patients in whom initial surgery was incomplete, elective second-look surgery may allow more complete clearance of tumor. "
10/01/1975 - "Second-look surgery should be performed for patients with retained ovaries and complete clinical regression of tumor after administration of chemotherapy and in selected patients in whom interval treatment permits surgical clearance of tumor. "
01/01/1998 - "Second-look surgery was carried out in the following situations: (1) tumor elements found in the washings of the peritoneum in Douglas' space and high blood-serum levels of CA-125 (8 patients with stage I-II tumors, in clinical remission); (2) during remission, after 6-10 courses of polychemotherapy (13 patients with stage III-IV tumors); (3) during remission, after non-radical primary surgery (117); (4) suspected recurrence (144); (5) recurrence-free surgical pathology, e.g. "
03/01/1994 - "Patients with no pathologic evidence of tumor at second-look surgery (negative second-look) are much more likely to experience a prolonged disease-free interval than are patients with evidence of gross tumors at second-look (macroscopic positive second-look). "
01/01/2023 - "Neoadjuvant chemotherapy and second-look surgery for pediatric pineal region tumors was considered to be effective in reducing the tumor volume and vascularity, which facilitates the safe maximal tumor resection."

11/01/2012 - "The technique is very helpful in differential diagnosis of cholesteatoma, mainly after canal wall-up tympanoplasty surgery, to avoid routine second-look surgery in these patients. "
03/01/2017 - "The oto-endoscopy led to a significant increase (p < .01) of the transcanalar approach and to a significant reduction (p < .05) of residual cholesteatoma at the second look surgery."
02/01/2011 - "Studies using DW-non-EPI and DWI-PROPELLER sequences show promising results related to improved diagnostic sensitivity and specificity for even small (<5 mm) cholesteatomas, thus allowing avoidance of second-look surgery in the future."
01/01/1999 - "Therefore second look surgery is the gold standard study to diagnosis a residual cholesteatoma. "
01/01/2009 - "TSE DW MRI holds great promise in screening for cholesteatoma as an alternative to exploratory second-look surgery."

04/01/1994 - "Stages II-IV ovarian cancer in pathologic complete remission (pCR) at second-look surgery have a high relapse rate (50%) during the first 2 years. "
05/01/1999 - "The therapeutic strategy for ovarian cancer may be improved for patients in CHR after second-look surgery by determining those at high risk, making it possible to confine consolidation treatment trials to such a group."
08/21/2012 - "The role of systematic aortic and pelvic lymphadenectomy (SAPL) at second-look surgery in early stage or optimally debulked advanced ovarian cancer is unclear and never addressed by randomised studies. "
04/30/2019 - ""Second look" surgery can detect small, poorly vascularized nodules of persistent ovarian cancer in ~50% of patients, where >80% are undergoing autophagy and express DIRAS3. "
02/01/2014 - "The role of pelvic and aortic lymphadenectomy at second look surgery in apparent early stage ovarian cancer after inadequate surgical staging followed by adjuvant chemotherapy."

05/01/1999 - "Prognosis of ovarian carcinoma in complete histologic remission (CHR) at second-look surgery is still controversial. "
05/01/1999 - "Prognostic factors in ovarian carcinoma in complete histologic remission at second-look surgery."
06/01/1996 - "Volume 60, Number 1 (1996), in the Society of Gynecologic Oncologists abstract "Randomized Study Comparing Systematic Pelvic (PE) and Aortic (A) Lymphadenectomy in Early Ovarian Carcinoma or at Second-Look Surgery versus No Lymphadenectomy: Feasibility and Complications," p. "
10/01/2012 - "Strategies to improve the results of carcinomatosis treatments include second-look surgery and hyperthermic intraperitoneal chemotherapy in patients at high risk for recurrence. "
01/01/2002 - "This investigation is a retrospective analysis to evaluate the influence of second-look surgery on the relapse-free and overall survival of patients with ovarian and tubal carcinomas. "

01/01/1996 - "Second-look surgery is performed after 6 cycles of first line polychemotherapy either to confirm a clinical complete remission pathohistologically or to debulk persisting residual tumors. "
09/01/1989 - "Second-look surgery with removal of residual tumor by gastrectomy and lymphadenectomy was performed in case of complete/partial remission (CR/PR) after EAP. "
01/01/1989 - "Twelve patients (30%) obtained a complete response (histologically confirmed after second look surgery in 6 cases, surgical complete response, residual tumor completely resected in the second look-in 5 cases and maintained complete clinical remission without second look confirmation in 1 case). "
01/01/2007 - "Persistent minimal residual disease diagnosed after the first line of chemotherapy during second-look surgery can be an indication for intraperitoneal chemotherapy. "
04/01/2002 - "Residual tumour was noted in the second case, but despite "second look" surgery there was subsequent local relapse."