HMGA Proteins

05/31/1982 - "The results indicate that HMGA is effective in reducing both bile cholesterol supersaturation and hypercholesterolemia. "
01/01/2023 - "The natural copolymer of SDG with HMGA (SDG polymer) is a source of bioactive compounds useful in prophylaxis of hypercholesterolemia. "

02/01/2022 - "HMGA proteins have been deeply involved in embryogenesis process, and a large volume of studies has pointed out their key role in human cancer. "
01/01/2015 - "Thereafter, several studies have analyzed HMGA expression in a wide range of human neoplasias. "
12/01/2004 - "Our studies indicate that HMGA molecules might be biologically and pathologically relevant factors in neuroblastic tumor development and progression."
09/12/2023 - "Selection of Natural Compounds with HMGA-Interfering Activities and Cancer Cell Cytotoxicity."
02/01/2021 - "The high mobility group A (HMGA) proteins are found to be aberrantly expressed in several tumors. "

01/01/2023 - "Network analysis showed enrichment of DE genes in pathways associated with cellular adhesion, oncogenesis and developmental regulation by mammalian AT-hook bearing high mobility group A (HMGA) proteins. "
09/04/2019 - "Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis."
01/01/2019 - "Here, we review the function of the HMGA proteins in human neoplastic disorders, the pathways by which they contribute to carcinogenesis and the new patents focused on targeting HMGA proteins. "
04/01/2012 - "PIT1 upregulation by HMGA proteins has a role in pituitary tumorigenesis."
09/15/2010 - "Different HMGA-dependent potential drives of pituitary oncogenesis are discussed as future research directions in the field."

01/01/2015 - "Numerous studies have established that High Mobility Group A (HMGA) proteins play a pivotal role on the onset of human pituitary tumors. "
12/15/2018 - "Retraction: HMGA Proteins Up-regulate CCNB2 Gene in Mouse and Human Pituitary Adenomas."
10/01/2015 - "Transgenic mice overexpressing the high mobility group A (HMGA) genes, Hmga1 or Hmga2 develop pituitary tumours and their overexpression is also a frequent finding in human pituitary adenomas. "
01/01/2015 - "Epigenetic Mechanisms Leading to Overexpression of HMGA Proteins in Human Pituitary Adenomas."
04/01/2012 - "Finally, the expression analysis of HMGA1, HMGA2 and PIT1 in human pituitary adenomas of different histological types revealed a direct correlation between PIT1 and HMGA expression levels. "

04/01/2018 - "In this review, we provide an overview of (i) the pathways involved in HMGA transcriptional and post-transcriptional regulation, (ii) the utilization of HMGA as molecular markers, and (iii) the biological role of HMGA in the context of breast cancer. "
04/01/2018 - "High Mobility Group A (HMGA) proteins: Molecular instigators of breast cancer onset and progression."
06/01/2015 - "High mobility group A1 (HMGA1), as a major member of HMGA family, plays an important part in promotion of cell proliferation and motility, induction of epithelial-mesenchymal transition, and maintenance of stemness, but little is known about the pathological role of HMGA1 in breast cancer patients. "
01/01/2010 - "To provide some clarity regarding the abundance of articles on this topic, here we focus on the relationship between HMGA proteins and breast cancer and their clinical perspective in the development of new therapeutic strategies."
01/01/2010 - "High-Mobility Group A (HMGA) Proteins and Breast Cancer."