Highly Active Antiretroviral Therapy (HAART)

Drug regimens, for patients with HIV INFECTIONS, that aggressively suppress HIV replication. The regimens usually involve administration of three or more different drugs including a protease inhibitor.

Also Known As:

Networked: 7338 relevant articles (657 outcomes, 858 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Bower, Mark: 40 articles (11/2012 - 03/2002)
2.	Anastos, Kathryn: 38 articles (01/2015 - 09/2002)
3.	Jacobson, Lisa P: 37 articles (10/2015 - 03/2002)
4.	Moore, Richard D: 36 articles (01/2014 - 01/2002)
5.	Margolick, Joseph B: 33 articles (10/2015 - 04/2002)
6.	Montaner, Julio S G: 33 articles (08/2015 - 09/2003)
7.	Manfredi, Roberto: 33 articles (08/2015 - 01/2002)
8.	Hogg, Robert S: 33 articles (04/2015 - 07/2002)
9.	Siliciano, Robert F: 32 articles (04/2014 - 02/2002)
10.	Hung, Chien-Ching: 30 articles (06/2013 - 03/2002)

Related Diseases

1.	Acquired Immunodeficiency Syndrome (AIDS) 09/01/2014 - "Since the introduction in 1996 of highly active anti-retroviral therapy (HAART), the landscape of malignancies associated to HIV/AIDS has changed in a significant manner as a direct result of significant improvement in the morbidity, mortality and life expectancy of HIV infected patients. " 06/01/2012 - "Although highly active anti-retroviral therapy (HAART) has obviously prohibited the progress of AIDS, a yearly increasing problems of human immunodeficiency virus (HIV) drug resistance have arousing more attention, affecting the clinical efficacy of HAART, and even resulting in treatment failure. " 01/01/2010 - "Highly active antiretroviral therapy (HAART) has dramatically improved health outcomes among people living with HIV/AIDS. " 06/01/2009 - "Although highly active antiretroviral therapy (HAART) has been extremely effective in lowering AIDS incidence among patients infected with HIV, certain drugs included in HAART can cause serious mitochondrial toxicities. " 06/01/2008 - "The introduction of highly active antiretroviral therapy (HAART) has dramatically improved the prognosis for individual patients with AIDS, but it has been education and a changing attitude to condoms that has led to a progressive fall in incidence, so that the worst of the epidemic may now be over. "
2.	HIV Infections (HIV Infection) 11/01/2012 - "The use of a potent combination of antiretroviral (ARV) drugs, so-called highly active ARV therapy (HAART), has dramatically improved the quality of life and overall survival of children with human immunodeficiency virus (HIV) infection. " 12/01/2010 - "The introduction of highly active antiretroviral therapy (HAART) has dramatically improved clinical outcomes in patients with human immunodeficiency virus (HIV) infection. " 07/01/2010 - "After the advent of HAART, the clinical course of HIV infection has dramatically improved. " 03/01/2010 - "The life expectancy of people living with HIV infection has improved dramatically since the use of highly active antiretroviral therapy (HAART). " 06/01/2007 - "Highly active antiretroviral treatment (HAART) has revolutionized the HIV treatment, leading to a significantly decreased morbidity, prolonged survival, and an overall better outcome of HIV infection. "
3.	Infection 07/01/2011 - "genavense infection in HIV-infected patients has dramatically improved with HAART. " 03/01/2011 - "Proviral DNAs are being measured increasingly as a marker of the efficacy of highly active anti-retroviral therapy (HAART) and is accepted for the early diagnosis of perinatal HIV-1 infections. " 01/01/2010 - "The availability of highly active anti-retroviral therapy (HAART) has greatly improved the outcome of human immunodeficiency virus type-1 (HIV-1) infection and disease. " 11/01/2009 - "The development of highly active antiretroviral therapy (HAART) to treat individuals infected with HIV-1 has dramatically improved patient outcomes, but HAART still fails to cure the infection. " 12/15/2007 - "Highly Active AntiRetroviral Therapies (HAART) can prolong life significantly to people infected by HIV since, although unable to eradicate the virus, they are quite effective in maintaining control of the infection. "
4.	Opportunistic Infections (Opportunistic Infection) 01/01/2005 - "A marked decrease in incidence has been observed for most central nervous system (CNS) opportunistic infections (OIs) after the use of highly active antiretroviral therapy (HAART) in developed countries. " 03/01/2015 - "Because highly active antiretroviral therapy has reduced incidence of opportunistic infections, it is important to reassess the efficacy of BMAB for this diagnostic purpose. " 07/01/2011 - "The use of highly active antiretroviral therapy (HAART) has been associated with a marked decrease in the prevalence of opportunistic infections in HIV-infected patients. " 06/01/2004 - "In industrialised countries, the use of Highly Active AntiRetroviral Therapy (HAART) results to be effective in suppressing the HIV viral load, with a quantitative and qualitative improvement in the CD4+ T-cell count followed by a strong reduction of opportunistic infections including those caused by parasites. " 05/01/2004 - "However, the introduction in 1996 of highly active antiretroviral therapy as a standard of care for those infected with HIV-1 determined a strong protection against the development of opportunistic infections, as well as a remission of pre-existing complications, including KS. "
5.	Lymphoma (Lymphomas) 04/01/2001 - "Most reports have insufficient data to analyze the impact of HAART therapy on incidence of central nervous system lymphomas, but recent data (from 1997 to 1999) showed a significant reduction in that risk. " 01/01/2010 - "The patient declined chemotherapy since he felt better after HAART, and rescanning at that time demonstrated marked improvement of the lymphoma on HAART alone. " 09/01/2003 - "The improved prognosis for patients with HIV-associated lymphoma in the post-HAART era indicates that therapeutic interventions may be potentially curative, and represent a shift away from therapeutic nihilism and reduced-intensity treatment approaches that have been employed in the recent past." 04/01/2005 - "To evaluate feasibility, safety, and efficacy of peripheral blood stem cell collection (PBSCC) and autologous stem cell transplantation (ASCT), to treat patients diagnosed of high-risk or relapsed HIV-associated lymphoma (HIV+ Ly), responding to highly active antiretroviral therapy (HAART). " 01/01/2010 - "HAART in addition to chemotherapy and/or radiotherapy is effective in improving the prognosis of plasmablastic lymphoma. "

Related Drugs and Biologics

1.	Protease Inhibitors (Protease Inhibitor)
2.	Reverse Transcriptase Inhibitors
3.	Lamivudine (3TC)
4.	Vincristine (Oncovin)
5.	cidofovir (Vistide)
6.	Carbon Monoxide
7.	Doxorubicin (Adriamycin)
8.	Zidovudine (Retrovir)
9.	HIV Protease Inhibitors
10.	RNA (Ribonucleic Acid)

Related Therapies and Procedures

1.	Highly Active Antiretroviral Therapy (HAART)
2.	Drug Therapy (Chemotherapy)
3.	Radiotherapy
4.	Aftercare (After-Treatment)
5.	Liver Transplantation