Euchromatin

Chromosome regions that are loosely packaged and more accessible to RNA polymerases than HETEROCHROMATIN. These regions also stain differentially in CHROMOSOME BANDING preparations.

Also Known As:

Networked: 166 relevant articles (1 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	van Bokhoven, Hans: 7 articles (01/2018 - 03/2010)
2.	Kleefstra, Tjitske: 5 articles (01/2018 - 03/2013)
3.	Benevento, Marco: 4 articles (10/2017 - 03/2013)
4.	Van der Zee, Catharina E E M: 4 articles (10/2017 - 03/2010)
5.	Balemans, Monique C M: 3 articles (02/2014 - 03/2010)
6.	Zhang, Yu: 2 articles (02/2022 - 05/2011)
7.	Kim, Inki: 2 articles (07/2019 - 11/2018)
8.	Kim, So Young: 2 articles (07/2019 - 11/2018)
9.	Chadwick, Brian P: 2 articles (01/2018 - 12/2015)
10.	Lim, Sai Kiang: 2 articles (12/2017 - 12/2014)

Related Diseases

1.	Psychotic Disorders (Schizoaffective Disorder) 01/01/2001 - "In affective psychosis, there was a significant reduction in the area of the nucleus and in the volume density of euchromatin and slight changes in cellular organelles. "
2.	Chromosome Breakage 06/01/2001 - "Chromosome breakage is the predominant effect, and this occurs primarily in the mouse euchromatin. " 05/01/1996 - "Compared with studies on gene replacement at the white locus, chromosomal breaks at su(f) appear to be less efficiently repaired from ectopic sites, perhaps because of the location of su(f) at the euchromatin/heterochromatin boundary on the X chromosome." 06/01/2001 - "The results of these studies indicate that benzene exposure is characterized by chromosome breakage, primarily within the euchromatin, and modest increases in aneuploidy. " 08/01/1995 - "Synergistic increase in chromosomal breakage within the euchromatin induced by an interaction of the benzene metabolites phenol and hydroquinone in mice."
3.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/2007 - "However, the absence of clinical effects has also been reported in some cases of chromosome abnormalities concerning euchromatin. " 02/01/2005 - "Given the significant amount of euchromatin demonstrated, it is likely that the chromosomal abnormalities are causative for the constellation of manifestations in this patient. " 01/01/1989 - "In the present study, an attempt has been made to evaluate the clastogenic sensitivity of heterochromatin and euchromatin using somatic chromosome complements of a submammalian vertebrate as experimental model and considering both chromosome aberrations and SCEs as end points." 12/01/2017 - "However, all mutants displayed anaphase bridges and chromosome aberrations resulting from the breakage of these bridges, predominantly at the euchromatin-heterochromatin junction. " 01/01/2014 - "Nevertheless, significant variation in the mean number of C-heterochromatin blocks in microchromosomes was attributed to either transformation of heterochromatin into euchromatin and vice versa or to involvement of structural chromosomal aberrations during karyotype evolution. "
4.	Lymphoma (Lymphomas) 09/01/1989 - "As compared to the lymphoblastic and polymorphic types, the follicular cleaved cell lymphoma has less euchromatin, less mitosis, slower growth rate and higher cohesiveness between tumor cells. " 06/01/1995 - "MALTomas and nodal lymphomas were distributed into 3 clusters: (1) with larger nuclei, light chromatin (euchromatin-richer) (5 MALTomas, 2 nodal lymphomas together with the control group); (2) nuclei with the same area size, but darker (eterochromatin-richer) (6 MALTomas and 1 nodal lymphoma); (3) with smaller and darker nuclei (5 MALTomas). " 01/01/2002 - "Here we show that in several KSHV/HHV-8-negative cell lines derived from carcinomas, sarcomas and lymphomas, RING3 was expressed at low levels, primarily localized to the euchromatin, and dissociated from the chromosomes during mitosis. " 05/01/1986 - "The purpose of this study is to examine effects of methylnitrosourea (MNU) on electron microscopic visualization of acridine orange (AO) binding to DNA in mouse lymphoma L-1210 cells and to demonstrate alteration of the euchromatin/heterochromatin ratio by morphometry. "
5.	Necrosis 01/01/2023 - "Histopathological study demonstrated that the untreated cells (control group) were regular cells with nuclear pleomorphism and hyperchromatic nuclei, while seed and peel extracts-treated cells showed necrosis, mixed euchromatin and heterochromatin, intra-nuclear eosinophilic structures, burst cell membranes, and the shrunken apoptotic cells with nuclear membranes and irregular cells. " 08/01/2008 - "The myocytes in the septum show, in FW conditions, nuclear polymorphism (heterochromatin, euchromatin), and two types (colliquative and coagulative) of necrosis. " 02/01/1997 - "Condensation of nuclear heterochromatin and loss of euchromatin was accompanied by cytoplasmic swelling and culminated in focal epidermal necrosis which was evident at 24 h after the challenge. "

Related Drugs and Biologics

1.	Heterochromatin
2.	Histone Methyltransferases
3.	Proteins (Proteins, Gene)
4.	DNA (Deoxyribonucleic Acid)
5.	Acridine Orange
6.	Benzene (Benzole)
7.	BIX 01294
8.	Methylnitrosourea (N-Methyl-N-nitrosourea)
9.	palbociclib
10.	Chromatin

Related Therapies and Procedures

1.	Therapeutics