Discrete Subaortic Stenosis

A type of constriction that is caused by the presence of a fibrous ring (discrete type) below the AORTIC VALVE, anywhere between the aortic valve and the MITRAL VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.

Also Known As:

Networked: 21 relevant articles (0 outcomes, 4 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Pathologic Constriction (Stenosis)
2.	Aortic Valve Insufficiency (Aortic Regurgitation)
3.	Ruptured Aneurysm
4.	Turner Syndrome (Turner's Syndrome)
5.	Splenomegaly

Experts

1.	Dunn, Stephen: 1 article (08/2014)
2.	Tsuda, Takeshi: 1 article (08/2014)
3.	Radtke, Wolfgang: 1 article (08/2014)
4.	Boyce, Steven: 1 article (07/2013)
5.	Mathias, Martin: 1 article (07/2013)
6.	Goldstein, Steven: 1 article (07/2013)
7.	Morrissey, Richard: 1 article (07/2013)
8.	Ahmad, Soha: 1 article (07/2013)
9.	Choi, Andrew D: 1 article (07/2013)
10.	Mesa, Dolores: 1 article (09/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Discrete Subaortic Stenosis:

1.	SASIBA 07/01/1997 - "The objective of this study was to show elevations in septal shear stress in response to morphologic abnormalities that have been associated with discrete subaortic stenosis (SAS) in children. " 07/01/2013 - "The case is reported of a patient with a previously undiagnosed cause of severe congestive heart failure (CHF) caused by the presence of a discrete subaortic stenosis (SAS) from a subvalvular membrane (SVM). " 11/01/2006 - "This study evaluates the progression of stenosis, onset and progression of aortic regurgitation (AR), and the results of surgical outcomes in children with isolated discrete subaortic stenosis (SAS). " 07/01/1998 - "A 10-year-old girl with discrete subaortic stenosis (SAS) and patent ductus arteriosus (PDA) was seen in December of 1996 with fever, hepatomegaly and splenomegaly. "
2.	CatecholaminesIBA 09/01/1988 - "The perioperative fate of residual gradients after repair of discrete subaortic stenosis and time-related blood levels of catecholamines."
3.	Idiopathic pulmonary hypertensionIBA 06/01/1981 - "Echocardiographic examination in a patient with primary pulmonary hypertension demonstrated midsystolic closure of the aortic valve, which has often been described in hypertrophic cardiomyopathy with or without obstruction, in discrete subaortic stenosis, and in ruptured aneurysm of the right coronary sinus of Valsalva. "
4.	Partial atrioventricular canalIBA 04/01/1985 - "Partial atrioventricular canal associated with discrete subaortic stenosis."
5.	Pulmonary venous return anomalyIBA 11/01/1988 - "Three cases of partial anomalous pulmonary venous return, in one case combined with coarctation of the aorta and in another with discrete subaortic stenosis, are described in patients with Turner syndrome. "
6.	Coarctation of the aortaIBA 11/01/1988 - "Three cases of partial anomalous pulmonary venous return, in one case combined with coarctation of the aorta and in another with discrete subaortic stenosis, are described in patients with Turner syndrome. "
7.	perfluoro- 2,2,2',2'- tetramethyl- 4,4'- bis(1,3- dioxolane)IBA 09/15/1986 - "Seven patients, mean age 8 +/- 3.6 years, with clinical and hemodynamic diagnoses of discrete subaortic stenosis were treated by percutaneous transluminal balloon dilatation (PTBD) of the membrane during cardiac catheterization. "
8.	A-factor (Streptomyces)IBA 01/01/1977 - "Bacterial endocarditis is very rare in patients with discrete subaortic stenosis, but it must be regarded as a factor complicating the natural history of cardiopathy."

Therapies and Procedures

1.	Balloon Dilation 09/27/2011 - "Long-term outcome of patients with isolated thin discrete subaortic stenosis treated by balloon dilation: a 25-year study." 11/01/1991 - "This study presents the findings in 33 patients with discrete subaortic stenosis who were treated by percutaneous balloon dilation and were followed up for 2 months to 6.2 years (mean 34 +/- 21 months). " 03/01/1999 - "Balloon dilation of discrete subaortic stenosis: are we postponing the inevitable?" 03/01/1999 - "Balloon dilation of discrete subaortic stenosis associated with other cardiac defects in children." 12/17/1994 - "We describe the successful percutaneous balloon valvuloplasty of a discrete subaortic stenosis in an adult patient. "
2.	Catheters 08/01/1987 - "Catheter balloon dilatation for discrete subaortic stenosis in the adult." 02/01/1996 - "A 37 year-old female patient underwent catheter-balloon dilation for discrete subaortic stenosis. "
3.	Transplants (Transplant) 08/01/2014 - "Acquired discrete subaortic stenosis in solid organ transplant recipients."