Neutral Amino Acids

11/01/1995 - "Protective effects of neutral amino acids against amphipathic drug-induced hemolysis."
10/01/1995 - "The protective effects of some neutral amino acids against hypotonic hemolysis were examined at various pHs. "
10/01/1995 - "Protective effects of some neutral amino acids against hypotonic hemolysis."

06/01/2008 - "These results suggest that the inhibition of LAT1 activity by BCH leads to apoptotic cancer cell death by inducing intracellular depletion of neutral amino acids necessary for cancer cell growth."
03/15/1987 - "Concentrations of the large neutral amino acids (LNAA) were determined in patients before and after tumor removal, and in postoperative patients before and after receiving either a standard TPN solution (STD-TPN), or a branched-chain amino acid solution (BCAA-TPN). "
12/03/1984 - "Studies in anorectic tumor-bearing rats indicate that anorexia is correlated to imbalances of neutral amino acids in blood and CNS. "
04/08/2009 - "LAT1, a subunit of heterodimeric system L transporter responsible for transporting neutral amino acids into cells, has been investigated in several cancers because of its onco-fetal nature. "
01/01/1991 - "The brains of anorectic tumor-bearing rats had increased levels of glutamine and most large neutral amino acids. "

12/03/1984 - "Studies in anorectic tumor-bearing rats indicate that anorexia is correlated to imbalances of neutral amino acids in blood and CNS. "
03/01/2008 - "Free tryptophan/large neutral amino acids ratios in blood plasma do not predict cerebral spinal fluid tryptophan concentrations in interleukin-1-induced anorexia."
01/01/1990 - "In case of patients with cancer anorexia a significant rise of the ratio in plasma between free and tryptophan/large neutral amino acids, competing with tryptophan for its brain entry, was observed. "
01/01/1990 - "To investigate the role of tryptophan in cancer anorexia, fasting plasma and CSF levels of tryptophan and other neutral amino acids were assayed in patients and controls. "
01/01/1996 - "There is evidence that the oral administration of neutral amino acids competing with tryptophan for brain entry results in a significant improvement of cancer anorexia. "

02/01/1996 - "In depressive disorders an association between basal pre-treatment plasma ratios of tryptophan (Trp) and tyrosine (Tyr) to other large neutral amino acids (LNAA) and the clinical efficacy of serotonergic acting drugs have been established. "
02/01/1983 - "Tryptophan and tyrosine ratios to neutral amino acids in endogenous depression. "
01/01/1994 - "The molar ratio of total plasma tryptophan (Trp) to the sum of the other large neutral amino acids (LNAAs), thought to reflect brain serotonin (5-HT) formation, was estimated in 47 patients with major depression (unipolar and bipolar) before and after 6 weeks of treatment with a serotonin uptake inhibitor, fluvoxamine. "

10/01/1995 - "To test the efficacy of a specially-formulated, carbohydrate-rich beverage (one known to increase the serum ratio of tryptophan to other large neutral amino acids) on the mood, cognitive, and appetitive disturbances of premenstrual syndrome (PMS). "
12/01/1991 - "We evaluated the ratio of plasma L-tryptophan to the sum of five competing neutral amino acids in women with premenstrual syndrome and in controls. "
12/01/1991 - "Tryptophan and neutral amino acids in premenstrual syndrome."