Protein Subunits (Protein Subunit)

Single chains of amino acids that are the units of multimeric PROTEINS. Multimeric proteins can be composed of identical or non-identical subunits. One or more monomeric subunits may compose a protomer which itself is a subunit structure of a larger assembly.

Also Known As:

Networked: 501 relevant articles (30 outcomes, 37 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Borroto-Escuela, Dasiel O: 8 articles (10/2022 - 07/2011)
2.	Fuxe, Kjell: 8 articles (10/2022 - 07/2011)
3.	Tarakanov, Alexander O: 4 articles (01/2017 - 07/2011)
4.	Dai, Lianpan: 3 articles (12/2022 - 01/2021)
5.	Gao, George F: 3 articles (12/2022 - 01/2021)
6.	Montefiori, David C: 3 articles (01/2021 - 04/2004)
7.	Ferraro, Luca: 3 articles (01/2020 - 01/2014)
8.	Tanganelli, Sergio: 3 articles (01/2020 - 01/2014)
9.	Aliesky, Holly A: 3 articles (12/2016 - 08/2009)
10.	McLachlan, Sandra M: 3 articles (12/2016 - 08/2009)

Related Diseases

1.	Infections 06/01/1999 - "Protection against Helicobacter pylori infection by intestinal immunisation with a 50/52-kDa subunit protein." 01/01/2020 - "Previous studies have shown 37.8 kDa pili subunit protein of Vibrio cholerae and 49.8 kDa pili subunit protein of Shigella flexneri can act as an adhesion molecule to initiate infection. " 01/01/2019 - "Host-pathogen interaction studies of the roles of flagella in infection, including due to uropathogenic Escherichia coli (UPEC), have used various methods to purify and examine the biology of the major flagella subunit protein, FliC. " 01/01/2023 - "One explanation behind PASC may be attributed to the recent discovery of persistent S1 protein subunit of SARS-CoV-2 in CD16+ monocytes up to 15 months after infection. " 12/10/2021 - "A key step in human immunodeficiency virus type 1 (HIV-1) infection is six-helix bundle formation within the envelope protein subunit gp41. "
2.	COVID-19 01/01/2022 - "Case report: Myocarditis following COVID-19 protein subunit vaccination." 12/01/2022 - "The Cuban Abdala protein subunit vaccine was highly effective in preventing severe illness and death from COVID-19 under real-life conditions. " 02/01/2023 - "This Phase 1 trial is a randomized, double-blind, placebo-controlled study to evaluate the safety and immunogenicity of the recombinant RBD-based protein subunit vaccine (Noora vaccine) against COVID-19 in healthy adults volunteers. " 02/01/2023 - "In the present study, we have evaluated the safety and immunogenicity of a recombinant receptor-binding domain (RBD)-based protein subunit vaccine (Noora vaccine) against COVID-19 in adults. " 02/01/2023 - "Safety and immunogenicity of a recombinant receptor-binding domain-based protein subunit vaccine (Noora vaccine™) against COVID-19 in adults: A randomized, double-blind, placebo-controlled, Phase 1 trial."
3.	Psoriasis (Pustulosis Palmaris et Plantaris) 10/01/2023 - "Guselkumab, an antibody targeting the p19 protein subunit of extracellular IL-23, is approved for the treatment of moderate-severe psoriasis, but evidence on its efficacy in treating HS is limited. " 10/01/2023 - "Guselkumab, an antibody targeting the p19 protein subunit of extracellular IL-23, is approved for the treatment of moderate-severe psoriasis, but evidence on its efficacy in treating HS is limited. "
4.	Dementia (Dementias) 06/01/2011 - "After treatment of Scu, the learning and memory ability was greatly improved, nAChRs alpha4 and alpha7 subunit protein expressions increased in rats with dementia (all P<0.05). " 12/01/2003 - "These data indicate no relationship between the trend for reduced neocortical alpha7 subunit protein expression in schizophrenia and dementia. " 06/01/2011 - "To observe the effect of Scutellarin (Scu) on expressions of nicotinic acetylcholine receptor (nAChR) subunit protein and mRNA in dementia rats, and to study its possible mechanism on dementia. " 02/24/1978 - "In this study the protein subunit of these paired helical filaments isolated from cases of Alzheimer's dementia was compared with the major protein subunits of normal neurofilaments and neurotubules by two-dimensional peptide maps of the tryptic or chymotryptic digests of these proteins labelled with 125I. " 04/01/1987 - "The relative molecular mass of the subunit protein, 4.0-4.5 kDa, is the same as the molecular mass of the amyloid of NFT, of the amyloid plaque cores, and of vascular amyloid deposits in Alzheimer disease and Down syndrome; the sequence of 15 amino acid residues at the N-terminus of the amyloid fibrils in the NFT of Guamanian parkinsonism-dementia is identical to that of the amyloid of NFT, amyloid plaque cores, and cerebrovascular deposits in Alzheimer disease and Down syndrome. "
5.	Coccidiosis 09/01/2011 - "The present study was conducted to compare aqueous nanoparticle-based Montanide™ IMS 1313 N VG PR (IMS 1313) and oil-based ISA 71 VG (ISA71) adjuvants in combination with an Eimeria subunit protein vaccine on protection against avian coccidiosis. " 09/20/2010 - "The current study was conducted to investigate the immunoenhancing effects of Montanide adjuvants on protein subunit vaccination against avian coccidiosis. "

Related Drugs and Biologics

1.	Vaccines
2.	Proteins (Proteins, Gene)
3.	DNA (Deoxyribonucleic Acid)
4.	COVID-19 Vaccines
5.	RNA (Ribonucleic Acid)
6.	Antigens
7.	Nucleic Acids
8.	DNA Vaccines
9.	Interferon-gamma (Interferon, gamma)
10.	Interleukin-23 (Interleukin 23)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Aftercare (After-Treatment)
3.	Organ Transplantation
4.	Highly Active Antiretroviral Therapy (HAART)
5.	Therapeutics