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Intrinsic Sleep Disorders

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Dyssomnias (i.e., insomnias or hypersomnias) associated with dysfunction of internal sleep mechanisms or secondary to a sleep-related medical disorder (e.g., sleep apnea, post-traumatic sleep disorders, etc.). (From Thorpy, Sleep Disorders Medicine, 1994, p187)

Also Known As:

Sleep Disorders, Intrinsic; Central Alveolar Hypoventilation Syndrome; Hypersomnia, Post-Traumatic; Hypersomnia, Posttraumatic; Sleep State Misperception; Hypersomnia, Post Traumatic; Hypersomnias, Post-Traumatic; Hypersomnias, Posttraumatic; Intrinsic Sleep Disorder; Post-Traumatic Hypersomnia; Post-Traumatic Hypersomnias; Posttraumatic Hypersomnia; Posttraumatic Hypersomnias; Sleep Disorder, Intrinsic; Sleep State Misperceptions

Networked: 9 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infarction
2.	Obstructive Sleep Apnea
3.	Narcolepsy
4.	Sleep Initiation and Maintenance Disorders (Insomnia)
5.	Brain Injuries (Brain Injury)

Experts

1.	Mishina, Masahiro: 1 article (01/2014)
2.	Kobayashi, Shiro: 1 article (01/2014)
3.	Ohkubo, Seiji: 1 article (01/2014)
4.	Mizunari, Takayuki: 1 article (01/2014)
5.	Kamiya, Nobuo: 1 article (01/2014)
6.	Suda, Satoshi: 1 article (01/2014)
7.	Sakamaki, Masanori: 1 article (01/2014)
8.	Katayama, Yasuo: 1 article (01/2014)
9.	Kominami, Shushi: 1 article (01/2014)
10.	Abe, Arata: 1 article (01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intrinsic Sleep Disorders:

1.	OxygenIBA 04/01/1997 - "In 180 healthy infants between 5 days and 18 months of age we performed respiratory CO2-responses during NREM-sleep and studied the immediate response to inhalation of 60% oxygen (Dejours test) as well as in 8 children with congenital central alveolar hypoventilation syndrome (CCHS) and 15 infants who experienced an apparently life-threatening event (ALTE). " 09/01/1997 - "The overall increase in whole body oxygen use was less than that seen in psychophysiological insomniacs but was consistent with the view that Sleep State Misperception insomnia may be a mild version or a precursor to psychophysiological insomnia."
2.	Polymethyl Methacrylate (Sol)IBA 10/01/2013 - "The pattern of subjective vs. objective SOL mismatch is suggestive of sleep-state misperception. "
3.	Almitrine (Vectarion)IBA 01/01/1983 - "Response to almitrine bismesylate in a child with a central alveolar hypoventilation syndrome."
4.	Carbon MonoxideIBA 05/01/2003 - "CFS patients had worse subjective sleep than their co-twins despite little objective data supporting this discrepancy, suggesting they suffer from an element of sleep-state misperception. "
5.	orexins (orexin)IBA 12/01/2003 - "One patient affected with post-traumatic hypersomnia had intermediate hypocretin levels. "
6.	pramipexol (pramipexole)FDA LinkGeneric 04/15/2009 - "Prospective evaluation of unselected traumatic brain injury patients with nocturnal polysomnography (NPSG), multiple sleep latency test (MSLT), Epworth Sleepiness Scale (ESS), and neuropsychological testing including Psychomotor Vigilance Test (PVT), Profile of Mood States (POMS), and Functional Outcome of Sleep Questionnaire (FOSQ) before and after treatment with continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA), modafinil (200 mg) for narcolepsy and posttraumatic hypersomnia (PTH), or pramipexole (0.375 mg) for periodic limb movements in sleep (PLMS). "
7.	modafinil (armodafinil)FDA Link 04/15/2009 - "Prospective evaluation of unselected traumatic brain injury patients with nocturnal polysomnography (NPSG), multiple sleep latency test (MSLT), Epworth Sleepiness Scale (ESS), and neuropsychological testing including Psychomotor Vigilance Test (PVT), Profile of Mood States (POMS), and Functional Outcome of Sleep Questionnaire (FOSQ) before and after treatment with continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA), modafinil (200 mg) for narcolepsy and posttraumatic hypersomnia (PTH), or pramipexole (0.375 mg) for periodic limb movements in sleep (PLMS). "
8.	A 7 (A-7)IBA 12/01/1985 - "Pulmonary function tests were performed in a 7 year-old girl with central alveolar hypoventilation syndrome treated with mechanical ventilation during sleep. "

Therapies and Procedures

1.	Tracheostomy 01/01/2014 - "Efficacy of tracheostomy for central alveolar hypoventilation syndrome caused by lateral medullary infarction."
2.	Continuous Positive Airway Pressure 04/15/2009 - "Prospective evaluation of unselected traumatic brain injury patients with nocturnal polysomnography (NPSG), multiple sleep latency test (MSLT), Epworth Sleepiness Scale (ESS), and neuropsychological testing including Psychomotor Vigilance Test (PVT), Profile of Mood States (POMS), and Functional Outcome of Sleep Questionnaire (FOSQ) before and after treatment with continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA), modafinil (200 mg) for narcolepsy and posttraumatic hypersomnia (PTH), or pramipexole (0.375 mg) for periodic limb movements in sleep (PLMS). "
3.	Artificial Respiration (Mechanical Ventilation) 12/01/1985 - "Pulmonary function tests were performed in a 7 year-old girl with central alveolar hypoventilation syndrome treated with mechanical ventilation during sleep. "
4.	Aftercare (After-Treatment) 04/15/2009 - "Prospective evaluation of unselected traumatic brain injury patients with nocturnal polysomnography (NPSG), multiple sleep latency test (MSLT), Epworth Sleepiness Scale (ESS), and neuropsychological testing including Psychomotor Vigilance Test (PVT), Profile of Mood States (POMS), and Functional Outcome of Sleep Questionnaire (FOSQ) before and after treatment with continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA), modafinil (200 mg) for narcolepsy and posttraumatic hypersomnia (PTH), or pramipexole (0.375 mg) for periodic limb movements in sleep (PLMS). "