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Q-Type Calcium Channels (Q-Type Calcium Channel)

CALCIUM CHANNELS located in the neurons of the brain.
Also Known As:
Q-Type Calcium Channel; Calcium Channels, Q-Type; Q-Type VDCC; Q-Type Voltage-Dependent Calcium Channels; Calcium Channel, Q-Type; Calcium Channels, Q Type; Channel, Q-Type Calcium; Q Type Calcium Channel; Q Type Calcium Channels; Q Type VDCC; Q Type Voltage Dependent Calcium Channels; VDCC, Q-Type
Networked: 99 relevant articles (2 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. van den Maagdenberg, Arn M J M: 7 articles (01/2022 - 07/2005)
2. Noebels, Jeffrey L: 5 articles (01/2020 - 02/2009)
3. Mark, Melanie D: 4 articles (11/2022 - 03/2011)
4. Lory, Philippe: 4 articles (10/2017 - 04/2008)
5. Snutch, Terrance P: 4 articles (01/2017 - 03/2009)
6. Herlitze, Stefan: 3 articles (01/2020 - 03/2011)
7. Motomura, Masakatsu: 3 articles (02/2019 - 01/2003)
8. Shiraishi, Hirokazu: 3 articles (02/2019 - 01/2003)
9. Mezghrani, Alexandre: 3 articles (10/2017 - 04/2008)
10. Garcia, Esperanza: 3 articles (01/2017 - 03/2009)

Related Diseases

1. Migraine with Aura (Familial Hemiplegic Migraine)
2. Seizures (Absence Seizure)
07/01/2010 - "Cav2.1 (P/Q-type) calcium channels control synaptic transmission at presynaptic nerve terminals, and mutations in the gene encoding the Cav2.1 alpha1 subunit (CACNA1A) have been linked to absence seizures in both humans and rodents. "
02/15/2005 - "Subsequent functional changes of T-type calcium channels in thalamus are observed in P/Q-type calcium channel mutant mice and these changes play important roles in generation of absence seizures. "
02/15/2005 - "Mutations in P/Q-type calcium channels generate common phenotypes in mice and humans, which are characterized by ataxia, paroxysmal dyskinesia, and absence seizures. "
07/01/1996 - "Omega-Conotoxin MVIIC (0.1, 0.3 micrograms ICV/mouse) and omega-agatoxin IVA (0.1, 0.3, 1 micrograms ICV), which act predominantly at P- and/or Q-type calcium channels, prevented clonic and tonic sound-induced seizures in this animal model of reflex epilepsy (ED50 values with 95% confidence limits for protection against clonic sound-induced seizures were 0.09 (0.04-0.36) micrograms ICV and 0.09 (0.05-0.15) micrograms ICV respectively and against tonic seizures 0.07 (0.03-0.16) micrograms ICV and 0.08 (0.04-0.13) micrograms ICV, respectively). "
01/04/2016 - "Recent insights provided by the identification of mutations in the P/Q-type calcium channel in humans and rodents with epilepsy and the finding of thalamic T-type calcium channel dysfunction in the absence of seizures have raised expectations of a causal role of calcium channels in the polygenic inheritance of idiopathic epilepsy. "
3. Reflex Epilepsy (Photosensitive Epilepsy)
4. Epilepsy (Aura)
5. Migraine Disorders (Migraine)

Related Drugs and Biologics

1. omega-Agatoxin IVA
2. Ion Channels (Ion Channel)
3. Adenosine Triphosphatases (ATPase)
4. omega-conotoxin-MVIIC
5. Pregabalin (Lyrica)
6. voltage-dependent calcium channel (P-Q type)
7. polyglutamine
8. Glutamic Acid (Glutamate)
9. Prostaglandins B
10. Anticonvulsants (Antiepileptic Drugs)

Related Therapies and Procedures

1. Therapeutics
2. Ligation