HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Brain Stem Infarctions (Weber Syndrome)

Subscribe to New Research on Brain Stem Infarctions

Infarctions that occur in the BRAIN STEM which is comprised of the MIDBRAIN; PONS; and MEDULLA OBLONGATA. There are several named syndromes characterized by their distinctive clinical manifestations and specific sites of ischemic injury.

Also Known As:

Weber Syndrome; Claude Syndrome; Foville Syndrome; Brainstem Infarctions; Brainstem Stroke; Infarctions, Brain Stem; Infarctions, Brainstem; Brain Stem Infarction; Brainstem Infarction; Infarction, Brain Stem; Infarction, Brainstem; Millard Gublar Syndrome; Stroke, Brainstem; Syndrome, Millard-Gublar; Benedict Syndrome; Millard-Gublar Syndrome; Top of the Basilar Syndrome

Networked: 103 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Meningitis
2.	Multiple Sclerosis
3.	Stroke (Strokes)
4.	Infarction
5.	Vertigo (Positional Vertigo)

Experts

1.	Lu, Zhengqi: 2 articles (01/2013 - 06/2012)
2.	Li, Haiyan: 2 articles (01/2013 - 06/2012)
3.	Kang, Zhuang: 2 articles (01/2013 - 06/2012)
4.	Dai, Yongqiang: 2 articles (01/2013 - 06/2012)
5.	Hu, Biao: 2 articles (01/2013 - 06/2012)
6.	Qiu, Wei: 2 articles (01/2013 - 06/2012)
7.	Ito, Masafumi: 2 articles (01/2012 - 01/2011)
8.	Ohno, Kinji: 2 articles (01/2012 - 01/2011)
9.	Ito, Mikako: 2 articles (01/2012 - 01/2011)
10.	Bain, Mark: 1 article (08/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Brain Stem Infarctions:

1.	tebufenozide (Mimic)IBA 05/01/1987 - "Early sequential BAER studies may be helpful in differentiating VB TIA from brain-stem infarction and syndromes that mimic VB TIA." 04/01/2002 - "Assisted reproductive technology-related acute psychiatric episodes, which may initially mimic brainstem stroke, are rare; however, attention should be paid to high-risk patients, and they should be offered elective psychological counselling." 01/01/2010 - "Acute vertigo with double vision - brainstem stroke or stroke mimic?"
2.	Hydroxyl RadicalIBA 01/01/2011 - "Administration of hydroxyl radical scavengers in acute stage of brainstem infarction improved MRI indices against the natural course. " 01/01/2011 - "We treated brainstem infarction patients in acute stage with hydroxyl radical scavengers (Edaravone and hydrogen) by intravenous administration and evaluated the effects of the treatment by a serial observation and analysis of these MRI indices. "
3.	OxygenIBA 12/01/2013 - "Late toxicity included grade 3 bitemporal lobe radionecrosis in 1 patient that improved with hyperbaric oxygen, a grade 4 cerebrospinal fluid leak with meningitis in 1 patient, and a grade 4 ischemic brainstem stroke (out of radiation field) in 1 patient, with subsequent neurologic recovery. "
4.	Cerebrospinal fluid leakIBA 12/01/2013 - "Late toxicity included grade 3 bitemporal lobe radionecrosis in 1 patient that improved with hyperbaric oxygen, a grade 4 cerebrospinal fluid leak with meningitis in 1 patient, and a grade 4 ischemic brainstem stroke (out of radiation field) in 1 patient, with subsequent neurologic recovery. "
5.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 02/01/2002 - "Our study highlights the frequency of small vessel disease as well as the relatively favorable prognosis in isolated brainstem infarction and preserved consciousness." 02/01/2002 - "In the remaining 340 patients with isolated brainstem infarction, the classification was: small vessel disease in 36.2%, macroangiopathy in 22.6%, and cardioembolism in 11.2%. " 11/01/2002 - "The patient returned 3 months after stent placement with severe neurological deterioration from a brainstem infarction caused by complete thrombotic occlusion of the left vertebral artery at the stented segment of the vessel. " 04/01/2012 - "We aim here to demonstrate the diagnostic value of gadolinium-enhanced magnetic resonance imaging (MRI) for demonstrating vessel wall abnormality in a child with brainstem stroke. "
6.	Olivopontocerebellar atrophy 2IBA 03/01/1981 - "We used electrooculography to study horizontal and vertical eye movements in 17 patients with downbeat nystagmus (Chiari malformation, 9; multiple sclerosis, 2; olivopontocerebellar atrophy, 2; brainstem infarction, 2; and idiopathic nystagmus, 2). "
7.	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/01/2001 - "Norepinephrine infusion therapy enabled all patients to sit, stay and walk around for more than 45 min. One patient died after a five-year treatment period, another after nine months because of nonhemorrhagic brain stem infarctions, both in the absence of norepinephrine treatment. " 01/01/1998 - "However, during the 5th year she suffered from nonhemorrhagic brain stem infarction due to cerebral hypoperfusion after orthostatic stress in the absence of noradrenaline infusion. " 07/01/1997 - "On the one hand, patients with brain stem infarction had substantially higher mean plasma norepinephrine levels than did patients with hemispheric infarction; on the other hand, hemispheric lesions were associated with a significantly higher incidence of cardiac arrhythmias when compared to patients with brain stem infarction."
8.	HydrogenIBA 04/01/2015 - "Beneficial effects of molecular hydrogen in clinical environment are observed especially in oxidative stress-mediated diseases, such as diabetes mellitus, brain stem infarction, rheumatoid arthritis, or neurodegenerative diseases. " 01/01/2011 - "In addition, hydrogen effects on humans have been reported in diabetes mellitus type 2, hemodialysis, metabolic syndrome, radiotherapy for liver cancer, and brain stem infarction. " 01/01/2011 - "We treated brainstem infarction patients in acute stage with hydroxyl radical scavengers (Edaravone and hydrogen) by intravenous administration and evaluated the effects of the treatment by a serial observation and analysis of these MRI indices. "
9.	Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA 10/01/1996 - "We discuss the relation of the intractable hiccups to the bilateral medial medullary lesions, and emphasize the importance of lupus anticoagulant as one of the risk factors in brainstem infarction." 01/01/1985 - "[Brain stem infarction, systemic lupus erythematosus and circulating lupus anticoagulant]."
10.	XenonIBA 11/01/1999 - "One hundred five patients with brain stem infarction detected by MR imaging underwent xenon contrast-enhanced CT to measure the regional CBF (rCBF) in the frontal, temporal, parietal, and occipital regions and in the putamen and thalamus. " 11/01/1999 - "Xenon contrast-enhanced CT imaging of supratentorial hypoperfusion in patients with brain stem infarction." 03/01/1979 - "Regional cerebral blood flow (rCBF) was measured by xenon 133 inhalation in 36 patients with vertebrobasilar arterial insufficiency (VBI), three patients with brain stem infarction, and 15 age-matched normal controls before and after inducing postural hypotension. "

Therapies and Procedures

1.	Ligation 01/01/2005 - "Authors conclude that superselective embolization of the maxillary artery in a patient with Rendu-Osler-Weber syndrome is safe and effective and can be a valuable alternative to the maxillary artery or the carotis externa artery ligation. "
2.	Stents 11/11/2008 - "The patency of the parent arteries was preserved in four DA patients with SAH (two Vertebral, two Basilar DA), 1 incidental vertebral DA, and one DA patient with brainstem infarction using stents and coils (four patients) or coils only (two patient). " 02/20/2007 - "One (3.3%) fatal brainstem infarction occurred 1 day after a successful ICA procedure, with angiographically proven acute basilar artery occlusion and patent ICA stent. " 01/01/2005 - "One patient developed brain stem infarction due to in-stent occlusion 8 months after stenting. " 08/01/2015 - "Follow-up at an average of 14.5 months showed complete angiographic occlusion in 4 (57.1%) cases, including one patient with in-stent thrombosis and major brainstem stroke at 4.5 months, a week after self-discontinuing dual antiplatelet therapy. " 10/01/2014 - "Compromise of perforating branches of the basilar artery resulting in brain stem infarctions has been described as a major complication of intracranial stent placement for basilar artery stenosis or after implantation of endovascular flow diverters. "
3.	Spinal Manipulation 07/01/1987 - "This case report should alert the forensic pathologist to the possibility of cervical manipulation as a cause of acute brainstem infarction, and the mechanism and the predisposing factors to injury should be reviewed. " 12/13/1978 - "A 23-year-old woman developed brainstem infarction following cervical manipulation. " 09/26/1980 - "Four cases of brainstem stroke syndromes followed mechanical cervical manipulation; vascular injury was confirmed angiographically. "
4.	Solid-State Lasers 08/01/1997 - "Nd:YAG laser therapy and other therapeutic options cannot obtain a lasting cure of Rendu-Osler-Weber syndrome. " 04/01/2000 - "A case of endoscopic neodymium:yttrium aluminium garnet (Nd:YAG) laser coagulation of a bladder hemangioma associated with Klippel-Weber syndrome is presented. " 04/01/2000 - "Endoscopic neodymium:yttrium aluminium garnet (Nd:YAG) laser irradiation of a bladder hemangioma associated with Klippel-Weber syndrome."
5.	Chiropractic Manipulation 12/01/1983 - "A case of brain stem infarction after chiropractic manipulation of the cervical spine is presented. " 12/01/1983 - "Brain stem infarction due to chiropractic manipulation of the cervical spine." 09/01/1983 - "A case of brain stem infarction after chiropractic manipulation of the cervical spine is presented. " 09/01/1983 - "Brain stem infarction due to chiropractic manipulation of the cervical spine."