Hypoglossal Nerve Diseases

Diseases of the twelfth cranial (hypoglossal) nerve or nuclei. The nuclei and fascicles of the nerve are located in the medulla, and the nerve exits the skull via the hypoglossal foramen and innervates the muscles of the tongue. Lower brain stem diseases, including ischemia and MOTOR NEURON DISEASES may affect the nuclei or nerve fascicles. The nerve may also be injured by diseases of the posterior fossa or skull base. Clinical manifestations include unilateral weakness of tongue musculature and lingual dysarthria, with deviation of the tongue towards the side of weakness upon attempted protrusion.
Also Known As:
Cranial Nerve XII Disorders; Hypoglossal Nerve Palsy; Hypoglossal Neuralgia; Hypoglossal Neuropathy; Twelfth Cranial Nerve Disorder; Hypoglossal Nerve Disease; Hypoglossal Nerve Palsies; Hypoglossal Neuralgias; Hypoglossal Neuropathies; Neuralgia, Hypoglossal; Neuralgias, Hypoglossal; Neuropathies, Hypoglossal; Neuropathy, Hypoglossal; Palsies, Hypoglossal Nerve; Palsy, Hypoglossal Nerve; Cranial Nerve XII Diseases; Twelfth Cranial Nerve Diseases
Networked: 29 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Dysarthria (Spastic Dysarthria)
2. Wounds and Injuries (Trauma)
3. Paresis (Hemiparesis)
4. Infarction
5. Horner Syndrome (Horner's Syndrome)


1. Mikasa, Michitaka: 1 article (12/2015)
2. Nakazato, Tomoko: 1 article (12/2015)
3. Taniguchi, Daisuke: 1 article (12/2015)
4. Nakajima, Sho: 1 article (12/2015)
5. Nakahara Ph D, Toshiki: 1 article (12/2015)
6. Furukawa Ph D, Yoshiaki: 1 article (12/2015)
7. Moglia, Cristina: 1 article (06/2015)
8. Fuda, Giuseppe: 1 article (06/2015)
9. Chiò, Adriano: 1 article (06/2015)
10. Ilardi, Antonio: 1 article (06/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hypoglossal Nerve Diseases:
1. MethylprednisoloneFDA LinkGeneric
2. Acyclovir (Aciclovir)FDA LinkGeneric
3. Nasopharyngeal carcinomaIBA
4. Medial Medullary SyndromeIBA
5. tebufenozide (Mimic)IBA
6. Amyloid (Amyloid Fibrils)IBA
7. Eagle syndromeIBA
8. papillary Thyroid cancerIBA

Therapies and Procedures

1. Denervation
2. Decompression
3. Radiotherapy
4. General Anesthesia
5. Transplants (Transplant)