Glial cell derived tumors arising from the optic nerve, usually presenting in childhood. Roughly 50% are associated with NEUROFIBROMATOSIS 1. Clinical manifestations include decreased visual acuity; EXOPHTHALMOS; NYSTAGMUS, PATHOLOGIC; STRABISMUS; pallor or swelling of the optic disc; and INTRACRANIAL HYPERTENSION. The tumor may extend into the optic chiasm and hypothalamus. (Adams et al., Principles of Neurology, 6th ed, p681)
Also Known As:
Adult Optic Nerve Glioma; Childhood Optic Nerve Glioma; Glioma, Optic Nerve, Adult; Glioma, Optic Nerve, Childhood; Malignant Optic Nerve Astrocytoma; Optic Glioma; Optic Nerve Glioma, Adult; Optic Nerve Glioma, Childhood; Optic Nerve, Malignant Astrocytoma; Glioma, Optic; Gliomas, Optic; Gliomas, Optic Nerve; Optic Gliomas; Optic Nerve Gliomas; Astrocytoma, Malignant, Optic Nerve; Glioma, Optic Nerve; Malignant Astrocytoma, Optic Nerve