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Vestibular Neuronitis (Vestibular Neuritis)

Idiopathic inflammation of the VESTIBULAR NERVE, characterized clinically by the acute or subacute onset of VERTIGO; NAUSEA; and imbalance. The COCHLEAR NERVE is typically spared and HEARING LOSS and TINNITUS do not usually occur. Symptoms usually resolve over a period of days to weeks. (Adams et al., Principles of Neurology, 6th ed, p304)
Also Known As:
Vestibular Neuritis; Acute Peripheral Vestibulopathy; Acute Vestibular Neuritis; Episodic Recurrent Vertigo; Recurrent Vestibular Neuritis; Recurrent Vestibulopathy; Subacute Vestibular Neuritis; Vestibular Nerve Inflammation; Vestibular Nerve Neuritis; Vestibular Neuropathy; Acute Peripheral Vestibulopathies; Acute Vestibular Neuritides; Epidemic Neurolabyrinthitides; Episodic Recurrent Vertigos; Inflammation, Vestibular Nerve; Inflammations, Vestibular Nerve; Nerve Inflammation, Vestibular; Nerve Inflammations, Vestibular; Nerve Neuritides, Vestibular; Nerve Neuritis, Vestibular; Neuritides, Acute Vestibular; Neuritides, Recurrent Vestibular; Neuritides, Subacute Vestibular; Neuritides, Vestibular; Neuritides, Vestibular Nerve; Neuritis, Acute Vestibular; Neuritis, Recurrent Vestibular; Neuritis, Subacute Vestibular; Neuritis, Vestibular Nerve; Neurolabyrinthitides, Epidemic; Neurolabyrinthitis, Epidemic; Neuronitides, Vestibular; Neuropathies, Vestibular; Neuropathy, Vestibular; Peripheral Vestibulopathies, Acute; Peripheral Vestibulopathy, Acute; Recurrent Vertigo, Episodic; Recurrent Vertigos, Episodic; Recurrent Vestibular Neuritides; Recurrent Vestibulopathies; Subacute Vestibular Neuritides; Vertigo, Episodic Recurrent; Vertigos, Episodic Recurrent; Vestibular Nerve Inflammations; Vestibular Nerve Neuritides; Vestibular Neuritides; Vestibular Neuritides, Acute; Vestibular Neuritides, Recurrent; Vestibular Neuritides, Subacute; Vestibular Neuritis, Acute; Vestibular Neuritis, Recurrent; Vestibular Neuritis, Subacute; Vestibular Neuronitides; Vestibular Neuropathies; Vestibulopathies, Acute Peripheral; Vestibulopathies, Recurrent; Vestibulopathy, Acute Peripheral; Vestibulopathy, Recurrent; Epidemic Neurolabyrinthitis; Neuritis, Vestibular; Neuronitis, Vestibular
Networked: 163 relevant articles (22 outcomes, 20 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Vertigo (Positional Vertigo)
2. Meniere Disease (Menieres Disease)
3. Dizziness (Lightheadedness)
4. Nausea
5. Benign Paroxysmal Positional Vertigo

Experts

1. Strupp, Michael: 14 articles (01/2018 - 07/2004)
2. Brandt, Thomas: 12 articles (07/2013 - 07/2004)
3. Dieterich, Marianne: 4 articles (01/2019 - 07/2004)
4. Strupp, M: 4 articles (01/2016 - 10/2001)
5. Chabbert, Christian: 3 articles (01/2022 - 01/2013)
6. Magnusson, Måns: 3 articles (01/2019 - 02/2004)
7. Tjernström, Fredrik: 2 articles (06/2022 - 01/2019)
8. Kim, Ji-Soo: 2 articles (01/2022 - 08/2013)
9. Péricat, David: 2 articles (01/2022 - 11/2021)
10. Rastoldo, Guillaume: 2 articles (01/2022 - 11/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vestibular Neuronitis:
1. Adrenal Cortex Hormones (Corticosteroids)IBA
2. SteroidsIBA
3. Betahistine (Serc)IBA
4. MethylprednisoloneFDA LinkGeneric
5. Carbamazepine (Tegretol)FDA LinkGeneric
02/01/2013 - "Although progress has been made in the diagnosis and treatment of most peripheral vestibular disorders, more state-of-the-art trials are needed on the treatment of bilateral vestibulopathy to prove the efficacy of balance training, of vestibular neuritis (in terms of recovery of peripheral vestibular function and central compensation), of vestibular paroxysmia to prove the effects of carbamazepine, and of Menière's disease to find the optimal dosage of betahistine."
01/01/2013 - "Considerable advances have been made in the treatment of vertigo disorders in the last 10 years, e.g., cortisone for the treatment of acute vestibular neuritis, betahistine as a high-dosage, long-term treatment for Menière's disease, carbamazepine to treat vestibular paroxysmia and aminopyridine for downbeat nystagmus and episodic ataxia type 2."
09/01/2013 - "Considerable advances have been made in the pharmacotherapy of vertigo disorders during the last 10 years, including cortisone for the treatment of acute vestibular neuritis, betahistine as a high-dose long-term treatment for Menière's disease, carbamazepine to treat vestibular paroxysmia and aminopyridine for down- and upbeat nystagmus and episodic ataxia type 2. "
07/01/2009 - "In vestibular neuritis, recovery of the peripheral vestibular function can be improved by oral corticosteroids; in Menière's disease, there is first evidence that high-dose, long-term administration of betahistine reduces attack frequency; carbamazepine or oxcarbamazepine is the treatment of first choice in vestibular paroxysmia, a disorder mainly caused by neurovascular cross-compression; the potassium channel blocker aminopyridine provides a new therapeutic principle for treatment of downbeat nystagmus, upbeat nystagmus, and episodic ataxia type 2."
03/01/2011 - "Examples of such causal therapy include aminopyridines for downbeat nystagmus and episodic ataxia type 2; carbamazepine for vestibular paroxysmia, paroxsymal dysarthria and ataxia in multiple sclerosis, and superior oblique myokymia; betahistine, dexamethasone, and gentamicin for Menière's disease; gabapentin and memantine for different forms of acquired and congenital nystagmus; corticosteroids for acute vestibular neuritis and Cogan's syndrome; metoprolol and topiramate for vestibular migraine; and selective serotonin reuptake inhibitors such as paroxetine for phobic postural vertigo. "
6. Dexamethasone (Maxidex)FDA LinkGeneric
7. Valacyclovir (Valtrex)FDA LinkGeneric
8. CortisoneFDA Link
9. Dimenhydrinate (DMH)FDA LinkGeneric
10. Cinnarizine (Cinna)IBA

Therapies and Procedures

1. Therapeutics
2. Exercise Therapy (Therapy, Exercise)
3. Drug Therapy (Chemotherapy)
08/01/2010 - "The authors retrospectively studied 2 cases of vascular compressive vestibular neuropathy about clinical characteristics, auditory tests, vestibular tests and imaging examine results, pharmacotherapy results and reviewed the related documents. "
04/01/2022 - "Various treatments for vestibular neuritis have been reported, which are largely divided into symptomatic therapy, specific drug therapy, and vestibular rehabilitation therapy. "
01/01/2014 - "To review the current knowledge of the aetiology of vestibular neuritis including viral infections, vascular occlusion, and immunomediated mechanisms and to discuss the pathogenesis with relevance to pharmacotherapy. "
01/01/2018 - "The results demonstrated the low accuracy of diagnosis of diseases manifested by vertigo and dizziness and high efficacy of non-drug therapy in most cases, especially BPPV, vestibular neuritis, Meniere's disease, postural phobic vertigo. "
01/01/2018 - "The etiology includes: idiopathic: n = 9, Wernicke's encephalopathy n = 11, superficial siderosis n = 3, paraneoplastic syndrome: n = 3, bilateral vestibular neuritis (recurrent AVS lasting days without cochlear symptoms) n = 3, simultaneous ototoxicity of aminoglycoside and chemotherapy toxicity n = 2, MELAS n = 2, Meniere's disease treated with intra-tympanic streptomycin in one ear n = 1, acute phenytoin intoxication: n = 1, combined chronic unilateral tumor-related vestibulopathy and new contralateral vestibular neuritis (this patient presented with Betcherew's phenomenon) n = 1, bilateral AICA stroke n = 1, mixed spinocerebellar ataxia type 3, n = 2 and CANVAS n = 2. "
4. Psychology Biofeedback (Biofeedback)
5. Aftercare (After-Treatment)