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Tics (Tic)

Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only brief periods. They often involve the face, vocal cords, neck, and less often the extremities. Examples include repetitive throat clearing, vocalizations, sniffing, pursing the lips, and excessive blinking. Tics tend to be aggravated by emotional stress. When frequent they may interfere with speech and INTERPERSONAL RELATIONS. Conditions which feature frequent and prominent tics as a primary manifestation of disease are referred to as TIC DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, pp109-10)
Also Known As:
Tic; Motor Tic; Habit Chorea; Habituation Spasm; Tic, Gestural; Tic, Transient; Chorea, Habit; Choreas, Habit; Gestural Tic; Gestural Tics; Habit Choreas; Habit Spasms; Habituation Spasms; Motor Tics; Spasm, Habit; Spasm, Habituation; Spasms, Habit; Spasms, Habituation; Tics, Gestural; Tics, Motor; Tics, Transient; Tics, Vocal; Transient Tic; Transient Tics; Vocal Tic; Vocal Tics; Habit Spasm; Tic, Motor; Tic, Vocal
Networked: 3866 relevant articles (321 outcomes, 560 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Tourette Syndrome (Tourette's Syndrome)
2. Tics (Tic)
3. Tic Disorders (Tic Disorder)
4. Neoplasms (Cancer)
5. Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)

Experts

1. Jankovic, Joseph: 27 articles (10/2022 - 03/2005)
2. Woods, Douglas W: 21 articles (01/2022 - 05/2010)
3. Cavanna, Andrea E: 21 articles (07/2021 - 12/2011)
4. Müller-Vahl, Kirsten R: 20 articles (05/2022 - 07/2002)
5. Martino, Davide: 17 articles (08/2022 - 08/2004)
6. Scahill, Lawrence: 17 articles (01/2022 - 01/2005)
7. Singer, Harvey S: 17 articles (01/2022 - 09/2007)
8. Leckman, James F: 16 articles (01/2022 - 01/2005)
9. Pringsheim, Tamara: 16 articles (12/2021 - 08/2003)
10. Piacentini, John: 15 articles (01/2022 - 10/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tics:
1. Antipsychotic Agents (Antipsychotics)IBA
2. Aripiprazole (Abilify)FDA Link
3. Clonidine (ST 155)FDA LinkGeneric
4. Botulinum Toxins (Botulinum Toxin)IBA
5. Risperidone (Risperdal Consta)FDA LinkGeneric
6. Haloperidol (Haldol)FDA LinkGeneric
7. Pimozide (Orap)FDA Link
8. Methylphenidate (Ritalin)FDA LinkGeneric
9. Biomarkers (Surrogate Marker)IBA
10. Guanfacine (Tenex)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Deep Brain Stimulation
3. Drug Therapy (Chemotherapy)
4. Aftercare (After-Treatment)
5. Injections