Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)
Also Known As:
CIDP; Polyradiculoneuropathy, Chronic Inflammatory; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Chronic Inflammatory Polyradiculoneuropathy; Inflammatory Polyradiculopathy, Chronic; Chronic Inflammatory Polyradiculoneuropathies; Chronic Inflammatory Polyradiculopathies; Chronic Inflammatory Polyradiculopathy; Inflammatory Polyradiculopathies, Chronic; Polyradiculoneuropathies, Chronic Inflammatory; Polyradiculopathies, Chronic Inflammatory; Polyradiculopathy, Chronic Inflammatory
Networked: 708 relevant articles (130 outcomes, 157 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
2. Polyneuropathies (Polyneuropathy)
3. Myasthenia Gravis
4. Dermatomyositis (Dermatopolymyositis)
5. Multiple Sclerosis


1. Dalakas, Marinos C: 18 articles (10/2015 - 12/2002)
2. Hughes, R A C: 18 articles (01/2014 - 04/2002)
3. Hughes, Richard A C: 17 articles (01/2015 - 01/2003)
4. Hartung, Hans-Peter: 16 articles (10/2015 - 04/2002)
5. Nobile-Orazio, Eduardo: 15 articles (10/2015 - 11/2003)
6. Latov, Norman: 14 articles (10/2015 - 06/2003)
7. Brannagan, Thomas H: 14 articles (02/2013 - 12/2002)
8. van Doorn, Pieter A: 13 articles (12/2015 - 06/2005)
9. Bril, Vera: 13 articles (10/2015 - 02/2008)
10. Merkies, Ingemar S J: 10 articles (10/2015 - 02/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chronic Inflammatory Demyelinating Polyradiculoneuropathy:
1. Intravenous Immunoglobulins (IVIG)FDA Link
2. Immunoglobulins (Immunoglobulin)IBA
3. Adrenal Cortex Hormones (Corticosteroids)IBA
4. Prednisone (Sone)FDA LinkGeneric
5. rituximab (Mabthera)FDA Link
6. AntibodiesIBA
7. GamunexIBA
8. Cyclosporine (Ciclosporin)FDA LinkGeneric
9. IceIBA
10. Cyclophosphamide (Cytoxan)FDA LinkGeneric

Therapies and Procedures

1. Plasma Exchange
2. Plasmapheresis
3. Immunotherapy
4. Aftercare (After-Treatment)
09/01/2005 - "We here initially retrospectively analyzed the motor nerve conduction study results of 20 consecutive patients with a clinical diagnosis of CIDP (four performed prior to, and 16 after, treatment initiation) to assess the sensitivity of six published sets of criteria (Nicolas et al., 2002; Thaisetthawatkul et al., 2002; Ad Hoc Subcommittee of the American Academy of Neurology AIDS Taskforce, 1991; Magda et al., 2003; Hughes et al., 2001; Saperstein et al., 2001), as well as four combinations (Nicolas et al., 2002; Ad Hoc Subcommittee of the American Academy of Neurology AIDS Taskforce, 1991; Hughes et al., 2001; Saperstein et al., 2001, each individually combined with Thaisetthawatkul et al., 2002). "
06/01/2003 - "This review offers an approach to the evaluation and management of patients with CIDP and highlights the difficult clinical problems in those who do not respond or frequently relapse after treatment with standard therapies such as patients with CIDP and concomitant axonal loss, and the assessment of those with CIDP and concurrent diseases such as diabetes mellitus."
10/01/2015 - "Follow-up nerve conduction studies in CIDP after treatment with IGIV-C: Comparison of patients with and without subsequent relapse."
01/01/2009 - "We report on a patient with CIDP who has been in remission for more than 3 years after treatment with high dose cyclophosphamide and autologous blood stem cell transplantation in CIDP on two occasions."
07/01/2008 - "To report a case of a patient with tremor associated with chronic inflammatory demyelinating neuropathy (CIDP) that improved after treatment with pregabalin. "
5. Stem Cell Transplantation