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Guillain-Barre Syndrome

An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Also Known As:
Acute Infectious Polyneuritis; Acute Inflammatory Demyelinating Polyneuropathy; Acute Inflammatory Polyradiculoneuropathy; Demyelinating Polyradiculoneuropathy, Acute Inflammatory; Guillain-Barre Syndrome, Familial; Guillain-Barré Syndrome; Guillaine-Barre Syndrome; Inflammatory Demyelinating Polyradiculoneuropathy, Acute; Inflammatory Polyneuropathy Acute; Polyneuropathy, Acute Inflammatory; Polyneuropathy, Inflammatory Demyelinating, Acute; Polyradiculoneuropathy, Acute Inflammatory Demyelinating; Acute Autoimmune Neuropathies; Acute Inflammatory Polyneuropathies; Acute Inflammatory Polyradiculoneuropathies; Autoimmune Neuropathies, Acute; Autoimmune Neuropathy, Acute; Familial Guillain-Barre Syndrome; Familial Guillain-Barre Syndromes; Guillain Barre Syndrome; Guillain Barre Syndrome, Familial; Guillain Barré Syndrome; Guillain-Barre Syndromes, Familial; Guillain-Barré Syndromes; Guillaine Barre Syndrome; Infectious Polyneuritis, Acute; Inflammatory Polyneuropathies, Acute; Inflammatory Polyneuropathy, Acute; Inflammatory Polyradiculoneuropathies, Acute; Landry Guillain Barre Syndrome; Neuropathy, Acute Autoimmune; Polyneuritis, Acute Infectious; Polyneuropathy Acute, Inflammatory; Polyradiculoneuropathies, Acute Inflammatory; Syndrome, Familial Guillain-Barre; Syndrome, Guillain-Barre; Syndrome, Guillain-Barré; Syndrome, Guillaine-Barre; Syndrome, Landry-Guillain-Barre; Acute Autoimmune Neuropathy; Acute Inflammatory Demyelinating Polyradiculoneuropathy; Acute Inflammatory Polyneuropathy; Landry-Guillain-Barre Syndrome; Polyradiculoneuropathy, Acute Inflammatory
Networked: 3729 relevant articles (173 outcomes, 326 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Polyneuropathies (Polyneuropathy)
2. Myasthenia Gravis
3. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
4. Dermatomyositis (Dermatopolymyositis)
5. Multiple Sclerosis

Experts

1. Yuki, Nobuhiro: 92 articles (12/2019 - 01/2002)
2. Jacobs, Bart C: 60 articles (01/2022 - 04/2002)
3. Kusunoki, Susumu: 51 articles (10/2021 - 01/2003)
4. van Doorn, Pieter A: 44 articles (01/2022 - 04/2003)
5. Willison, Hugh J: 40 articles (01/2022 - 04/2002)
6. Kuwabara, Satoshi: 30 articles (10/2021 - 03/2002)
7. Yuki, N: 30 articles (10/2011 - 02/2000)
8. Koga, Michiaki: 22 articles (06/2022 - 07/2002)
9. Zhang, Hong-Liang: 22 articles (07/2021 - 09/2010)
10. Zhu, Jie: 22 articles (07/2021 - 10/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Guillain-Barre Syndrome:
1. Intravenous Immunoglobulins (IVIG)FDA Link
2. Adrenal Cortex Hormones (Corticosteroids)IBA
3. Immunoglobulin G (IgG)IBA
4. Immunoglobulins (Immunoglobulin)IBA
5. SteroidsIBA
6. AntibodiesIBA
7. MethylprednisoloneFDA LinkGeneric
8. Complement System Proteins (Complement)IBA
9. VaccinesIBA
10. GangliosidesIBA

Therapies and Procedures

1. Plasma Exchange
2. Therapeutics
3. Plasmapheresis
4. Immunotherapy
5. Blood Component Removal (Apheresis)