Guillain-Barre Syndrome

An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Also Known As:
Acute Inflammatory Demyelinating Polyneuropathy; Acute Inflammatory Polyradiculoneuropathy; Demyelinating Polyradiculoneuropathy, Acute Inflammatory; Guillaine-Barre Syndrome; Inflammatory Demyelinating Polyradiculoneuropathy, Acute; Inflammatory Polyneuropathy Acute; Polyneuropathy, Acute Inflammatory; Polyradiculoneuropathy, Acute Inflammatory Demyelinating; Acute Autoimmune Neuropathies; Acute Inflammatory Polyneuropathies; Acute Inflammatory Polyradiculoneuropathies; Acute, Inflammatory Polyneuropathy; Autoimmune Neuropathies, Acute; Autoimmune Neuropathy, Acute; Guillain Barre Syndrome; Guillaine Barre Syndrome; Inflammatory Polyneuropathies, Acute; Inflammatory Polyneuropathy Acutes; Inflammatory Polyneuropathy, Acute; Inflammatory Polyradiculoneuropathies, Acute; Landry Guillain Barre Syndrome; Neuropathies, Acute Autoimmune; Neuropathy, Acute Autoimmune; Polyneuropathies, Acute Inflammatory; Polyneuropathy Acute, Inflammatory; Polyradiculoneuropathies, Acute Inflammatory; Syndrome, Guillain-Barre; Syndrome, Guillaine-Barre; Syndrome, Landry-Guillain-Barre; Acute Autoimmune Neuropathy; Acute Inflammatory Demyelinating Polyradiculoneuropathy; Acute Inflammatory Polyneuropathy; Landry-Guillain-Barre Syndrome; Polyradiculoneuropathy, Acute Inflammatory
Networked: 417 relevant articles (15 outcomes, 38 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Multiple Sclerosis
2. Polyneuropathies (Polyneuropathy)
3. Myasthenia Gravis
4. Demyelinating Diseases (Demyelinating Disease)
5. Systemic Lupus Erythematosus (Libman-Sacks Disease)


1. Yuki, Nobuhiro: 17 articles (12/2015 - 03/2002)
2. Kuwabara, Satoshi: 14 articles (01/2015 - 03/2002)
3. Kusunoki, Susumu: 7 articles (05/2015 - 10/2004)
4. Mori, Masahiro: 5 articles (11/2015 - 08/2002)
5. Hirata, Koichi: 5 articles (07/2014 - 03/2002)
6. Hattori, T: 5 articles (03/2005 - 10/2000)
7. Kuwabara, S: 5 articles (03/2005 - 10/2000)
8. Misawa, Sonoko: 4 articles (07/2014 - 01/2004)
9. Jacobs, Bart C: 4 articles (06/2013 - 12/2004)
10. Odaka, Masaaki: 4 articles (12/2012 - 08/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Guillain-Barre Syndrome:
1. Intravenous Immunoglobulins (IVIG)FDA Link
2. Immunoglobulins (Immunoglobulin)IBA
3. Adrenal Cortex Hormones (Corticosteroids)IBA
4. Prednisolone (Predate)FDA LinkGeneric
5. Cytostatic AgentsIBA
6. Cyclophosphamide (Cytoxan)FDA LinkGeneric
7. Cholinesterase Inhibitors (Anticholinesterases)IBA
8. Azathioprine (Imuran)FDA LinkGeneric
9. Analgesics (Analgesic Drugs)IBA
10. Hashimoto's encephalitisIBA

Therapies and Procedures

1. Plasmapheresis
2. Immunotherapy
3. Plasma Exchange
4. Blood Component Removal (Apheresis)
5. Immunomodulation