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Ideomotor Apraxia

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A form of apraxia characterized by an acquired inability to carry out a complex motor activity despite the ability to mentally formulate the action. This condition has been attributed to a disruption of connections between the dominant parietal cortex and supplementary and premotor cortical regions in both hemispheres. (From Adams et al., Principles of Neurology, 6th ed, p57)

Also Known As:

Apraxia, Ideomotor; Apraxia, Ideokinetic; Apraxia, Limb Kinetic; Apraxia, Transcortical; Classic Apraxia; Apraxia, Classic; Apraxias, Classic; Apraxias, Ideokinetic; Apraxias, Ideomotor; Apraxias, Limb Kinetic; Apraxias, Transcortical; Classic Apraxias; Dyspraxias, Ideomotor; Ideokinetic Apraxia; Ideokinetic Apraxias; Ideomotor Apraxias; Ideomotor Dyspraxia; Ideomotor Dyspraxias; Kinetic Apraxia, Limb; Kinetic Apraxias, Limb; Limb Kinetic Apraxia; Limb Kinetic Apraxias; Transcortical Apraxia; Transcortical Apraxias; Dyspraxia, Ideomotor

Networked: 20 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Apraxias (Dyspraxia)
2.	Stroke (Strokes)
3.	Paralysis (Palsy)
4.	Paresis (Hemiparesis)
5.	Hemorrhage

Experts

1.	Atalay, Ayce: 1 article (04/2015)
2.	Civelek, Gul Mete: 1 article (04/2015)
3.	Turhan, Nur: 1 article (04/2015)
4.	Convento, Silvia: 1 article (02/2015)
5.	Mattioli, Flavia: 1 article (02/2015)
6.	Vallar, Giuseppe: 1 article (02/2015)
7.	Tesio, Luigi: 1 article (02/2015)
8.	Bolognini, Nadia: 1 article (02/2015)
9.	Banco, Elisabetta: 1 article (02/2015)
10.	Barrero-Hernandez, Francisco J: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ideomotor Apraxia:

1.	Amantadine (Aman)FDA LinkGeneric 01/01/2015 - "Dressing and ideomotor apraxia were reportedly responsive to amantadine. " 08/01/2001 - "By administration of amantadine, rigidity and cortical sensory loss did not improve, but some praxic impairments, such as dressing apraxia and ideomotor apraxia, and the EEG improved. "
2.	Levodopa (L Dopa)FDA LinkGeneric 05/01/1991 - "The group with frozen gait (4 cases, aged 78 to 82 years) which failed to respond to L-dopa therapy, had no limb-kinetic apraxia or frontal signs, but did exhibit "kinésie paradoxale". " 02/01/1998 - "The results confirm that unilateral parkinsonism unresponsive to levodopa and limb ideomotor apraxia are the clinical hallmarks of corticobasal degeneration, and only a minority of patients with corticobasal degeneration present with dementia. " 05/01/2004 - "Atypical parkinsonism (AP) is a term applied to disorders characterized by parkinsonism that evolves rapidly, with poor or transient response to levodopa, or has other associated features such as early falls and postural instability, early autonomic failure, supranuclear gaze palsy, pyramidal or cerebellar signs, alien hand syndrome or severe ideomotor apraxia. " 08/01/2001 - "L-dopa had no effect on the symptoms of rigidity, limb kinetic apraxia, cortical sensory loss, ideomotor apraxia, and dressing apraxia. "
3.	2-methylcyclopentadienyl manganese tricarbonyl (MMT)IBA 04/01/2015 - "Assessment tools included Ideomotor Apraxia Test, Functional Independence Measure (FIM), Brunnstrom recovery stages, Mini Mental Test (MMT), and star cancellation test. " 01/01/2002 - "A separate observer performed the minimental test (MMT), Barthel index, geriatric depression score (GDS), ideational dyspraxia test (IDT), and ideomotor dyspraxia test (IMD). "
4.	Dopamine (Intropin)FDA LinkGeneric 12/01/2009 - "At least one small report has suggested the possibility that limb kinetic apraxia (a deficit in deftness) was not dopamine responsive and independent of bradykinesia and rigidity in PD. "
5.	Coffee FDA Link 01/01/2013 - "Dysfunction of the former produces ideomotor apraxia (e.g., difficulty using scissors), and dysfunction of the latter induces ideational apraxia (e.g., difficulty making a cup of coffee). "
6.	Carbon MonoxideIBA 01/01/2011 - "We distinguished from two patterns of "pure" developmental dyspraxia: ideomotor and visual-spatial/visual-constructional, and mix dyspraxia with more co-morbidities. "
7.	Amyloid (Amyloid Fibrils)IBA 08/01/2013 - "Although asymmetric rigidity and limb-kinetic apraxia strongly suggested corticobasal degeneration, (11)C-Pittsburgh compound B positron emission tomography (PiB-PET) showed the predominantly right-sided accumulation of amyloid β in the cortices and striatum. "
8.	Amyloid angiopathyIBA 01/01/2001 - "Compared with the other groups, pDLB cases had more frequent acute-subacute onset of dementia [45% vs. AD (3%) and AD+LB (16%)], early parkinsonism [45% vs. AD (0%) and AD+LB (0%)], early [27% vs. AD (0%) and AD+LB (0%)] and late [73% vs. AD (11%) and AD+LB (16%)] hallucinations, fluctuating course [46% vs. AD (9%) and AD+LB (22%)], delusions [45% vs. AD (11%) and AD+LB (6%)], spontaneous parkinsonism [63% vs. AD (8%) and AD+LB (16%)], less frequent ideomotor apraxia and loss of insight, earlier urinary incontinence [3.2 +/- 1.4 years after onset vs. AD (6.3 years) and AD+LB (5.8 years)], shorter duration of dementia [7.7 +/- 2.4 years vs. AD (9.6 years) and AD+LB (11 years)], milder atrophy in computed tomography scans, greater brain weight, more transcortical spongiosis, wider cortex and subcortex, and less amyloid angiopathy. "
9.	ruberythric acid (AlP)IBA 08/01/2012 - "ALP was either initially or eventually accompanied by ipsilateral hemineglect, ideomotor apraxia and/or cortical sensory loss in nine patients. "
10.	propyl O-beta galactopyranosyl-(1-4)-O-beta galactopyranosyl-(1-4)-alpha galactopyranosideIBA 04/01/2007 - "Here, we report the novel G335S mutation, which changes the PGGG motif of the third tau repeat to PGGS, in an individual who developed social withdrawal, emotional bluntness and stereotypic behavior at age 22, followed by disinhibition, hyperorality and ideomotor apraxia. "

Therapies and Procedures

1.	Activities of Daily Living (ADL) 06/01/2008 - "The aim of this study was to investigate the effect of ideomotor apraxia on activities of daily living and to determine if the presence of apraxia interferes with rehabilitation. " 01/01/2011 - "The aim of the present article is to describe the most important subtypes of apraxia such as ideational and ideomotor apraxia as well as their impact on ADL and outcome. " 01/01/2015 - "Secondary outcome measures will include the following: 1) the Lawton and Brody Instrumental Activities of Daily Living Scale, 2) the Observation and Scoring of ADL-Activities, 3) the De Renzi Test for Ideational Apraxia, 4) the De Renzi Test for Ideomotor Apraxia, 5) Recognition of Gestures, 6) the Test of Upper Limb Apraxia (TULIA), and 7) the Quality of Life Scale For Stroke (ECVI-38). " 03/01/2003 - "The following factors were found in one level A study: initial ADL disability and ambulation, high age, severe paresis or paralysis, impaired swallowing, ideomotor apraxia, ideational apraxia, and visuospatial construction problems; as well as factors relating to complications of an ischaemic stroke, such as extraparenchymal bleeding, cerebral oedema and size of intraparenchymal haemorrhage. " 06/01/2008 - "All the patients were assessed at their admission and discharge, respectively, for apraxia by Ideomotor Apraxia Test, for daily living activities by Functional Independence Measure (FIM, Santa Clara Valley Medical Center, San Jose, California, USA), for cognitive functions by Mini Mental State Examination (MMSE), and for language components by Gulhane Aphasia Test (GAT). "
2.	Anesthesia 08/22/2000 - "This study was conducted to learn the relationship between limb-kinetic apraxia and hemisphere dysfunction by using selective hemisphere anesthesia, the Wada test. "