Transient Global Amnesia

A syndrome characterized by a transient loss of the ability to form new memories. It primarily occurs in middle aged or elderly individuals, and episodes may last from minutes to hours. During the period of amnesia, immediate and recent memory abilities are impaired, but the level of consciousness and ability to perform other intellectual tasks are preserved. The condition is related to bilateral dysfunction of the medial portions of each TEMPORAL LOBE. Complete recovery normally occurs, and recurrences are unusual. (From Adams et al., Principles of Neurology, 6th ed, pp429-30)

Also Known As:

Networked: 70 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Amnesia (Dissociative Amnesia)
2.	Thrombocytopenia (Thrombopenia)
3.	Retrograde Amnesia
4.	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis)
5.	Anterograde Amnesia

Experts

1.	Bartsch, Thorsten: 2 articles (11/2015 - 02/2013)
2.	Forsström, Fredrik: 1 article (12/2015)
3.	Jalanko, Mikko: 1 article (12/2015)
4.	Lassus, Johan: 1 article (12/2015)
5.	Jansen, Olav: 1 article (11/2015)
6.	Rohr, Axel: 1 article (11/2015)
7.	Brauer, Henriette: 1 article (11/2015)
8.	Döhring, Juliane: 1 article (11/2015)
9.	Reuter, Sigrid: 1 article (11/2015)
10.	Deuschl, Günther: 1 article (11/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Transient Global Amnesia:

1.	Brain-Derived Neurotrophic Factor (BDNF)IBA 10/10/2008 - "The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is not significantly correlated to Transient Global Amnesia: preliminary results of an on-going study in Brescia Province, Italy."
2.	TeaIBA 11/01/1993 - "The anatomical and pathophysiological basis of TEA is presumed to be similar to transient global amnesia (TGA), that is, it is likely to be primarily hippocampal in origin, but with more variable involvement of limbic and adjacent temporal lobe neocortical structures." 02/01/2013 - "Critical clinical distinctions, such as between transient global amnesia (TGA) and transient epileptic amnesia (TEA), as well as important clues to the underlying pathophysiology, have recently been revealed. " 05/01/2008 - "An isolated prolonged episode of transient amnesia can be a major manifestation of transient global amnesia (TGA) and transient epileptic amnesia (TEA). " 10/01/2000 - "Abbreviations : AA: anterograde amnesia; AMI: Autobiographical Memory Interview; PTA: posttraumatic amnesia; RA: retrograde amnesia; RMT: Recognition Memory Test; TEA: transient epileptic amnesia; TGA: transient global amnesia; WMS: Wechsler Memory Scale."
3.	sildenafil (Viagra)FDA Link 07/16/2014 - "[Transient global amnesia associated to sildenafil and sexual activity]." 09/01/2006 - "Scanty data are available regarding Sildenafil and cerebrovascular disease and there are only a few case reports regarding transient global amnesia (TGA) after Sildenafil use. " 09/01/2006 - "[Two cases of transient global amnesia (TGA) following sildenafil use]." 10/01/2003 - "Sildenafil and transient global amnesia." 09/10/2002 - "Transient global amnesia after sildenafil (Viagra) use."
4.	Heparin (Liquaemin)FDA LinkGeneric 05/01/2010 - "A 57-year-old man developed transient global amnesia within an hour of bolus unfractionated heparin administration on day 4 post-mitral valve replacement. " 07/01/2010 - "Comments on: Transient global amnesia as the presenting feature of heparin-induced thrombocytopenia." 05/01/2010 - "Transient global amnesia as the presenting feature of heparin-induced thrombocytopenia." 11/01/1994 - "Transient global amnesia associated with acute heparin-induced thrombocytopenia."
5.	BenzodiazepinesIBA 05/01/2002 - "Is transient global amnesia related to endogenous benzodiazepines?" 09/01/1990 - "Benzodiazepine derivates can cause transient global amnesia even when administered in therapeutical doses. " 05/01/1989 - "Alcoholic blackout, benzodiazepine-induced amnesia and transient global amnesia are three disorders that result in acute transient memory loss. "
6.	tadalafil (Cialis)FDA Link 01/01/2010 - "Tadalafil-induced transient global amnesia." 06/14/2008 - "[Transient global amnesia after tadalafil use]." 07/01/2005 - "We describe a patient who had a transient global amnesia (TGA) after his first-ever use of tadalafil, a potent PDE-5 inhibitor. " 07/01/2005 - "Transient global amnesia after intake of tadalafil, a PDE-5 inhibitor: a possible association?"
7.	Antiphospholipid AntibodiesIBA 05/01/2006 - "Transient global amnesia in a patient with high and persistent levels of antiphospholipid antibodies." 01/01/1989 - "The presence in this patient of antiphospholipid antibodies suggests a vascular mechanism for transient global amnesia." 01/01/1989 - "Transient global amnesia and antiphospholipid antibodies."
8.	XenonIBA 07/01/2001 - "We examined her cerebral blood flow(CBF) immediately during transient global amnesia(TGA) by stable xenon enhanced CT scans(Xe-CT) and twice thereafter. " 01/01/1987 - "Cerebral blood flow determinations using the Xenon inhalation test in two patients with transient global amnesia showed overall decreases during the attack with a more marked fall in temporal-inferior frontal flow in one case and in temporal flow in the other. "
9.	OxygenIBA 09/01/1997 - "To assess explicit memory and two components of implicit memory--that is, perceptual-verbal skill learning and lexical-semantic priming effects--as well as resting cerebral blood flow (CBF) and oxygen metabolism (CMRO2) during the acute phase of transient global amnesia. " 09/01/1997 - "Transient global amnesia: implicit/explicit memory dissociation and PET assessment of brain perfusion and oxygen metabolism in the acute stage." 01/01/1992 - "Regional cerebral blood flow (rCBF), cerebral metabolic rate of oxygen (rCMRO2), and oxygen extraction fraction (rOEF) were measured using positron emission tomography (PET) in four patients with cirrhosis (two males and two females, aged 57 to 69 years) in comparison with those in five age-matched controls with previous transient global amnesia. "
10.	Iopamidol (Isovue)FDA LinkGeneric 01/01/1990 - "Transient global amnesia associated with cerebral angiography performed with use of iopamidol." 07/01/1989 - "The authors describe two patients who developed transient global amnesia after they underwent cerebral angiography with iopamidol. " 07/01/1989 - "Transient global amnesia associated with cerebral angiography performed with use of iopamidol."

Therapies and Procedures

1.	General Anesthesia 09/01/2005 - "Transient global amnesia after general anesthesia." 04/01/1998 - "[Transient global amnesia after general anesthesia]." 06/01/1985 - "Transient global amnesia following general anesthesia." 07/01/2012 - "We report an incident of probable transient global amnesia in a patient after endoscopic retrograde cholangiopancreatogram under general anesthesia, which was successfully treated with flumazenil. "
2.	Angioplasty (Angioplasty, Transluminal) 01/01/2006 - "Transient global amnesia following vertebral artery angioplasty and stenting." 07/01/2005 - "Transient global amnesia following coronary angiography and angioplasty."
3.	Intravitreal Injections 08/01/2009 - "Transient global amnesia following intravitreal injection of bevacizumab."
4.	Deep Brain Stimulation 01/01/2013 - "Transient global amnesia associated with accidental high-frequency stimulation of the right hippocampus in deep brain stimulation for segmental dystonia." 01/01/2013 - "We report on a 66-year-old woman with segmental dystonia treated with chronic bilateral deep brain stimulation of the globus pallidus internus, in whom accidental high-voltage, high-frequency stimulation induced an episode of transient global amnesia (TGA) via an electrode contact which was misplaced in the right hippocampus. "
5.	Anterior Temporal Lobectomy 03/01/2008 - "Is anterior temporal lobectomy a precipitating factor for transient global amnesia?"