Transient Global Amnesia

A syndrome characterized by a transient loss of the ability to form new memories. It primarily occurs in middle aged or elderly individuals, and episodes may last from minutes to hours. During the period of amnesia, immediate and recent memory abilities are impaired, but the level of consciousness and ability to perform other intellectual tasks are preserved. The condition is related to bilateral dysfunction of the medial portions of each TEMPORAL LOBE. Complete recovery normally occurs, and recurrences are unusual. (From Adams et al., Principles of Neurology, 6th ed, pp429-30)

Also Known As:

Networked: 108 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Amnesia (Dissociative Amnesia)
2.	Thrombocytopenia (Thrombopenia)
3.	Stroke (Strokes)
4.	Limbic Encephalitis (Paraneoplastic Limbic Encephalitis)
5.	Neoplasms (Cancer)

Experts

1.	Assenza, Giovanni: 2 articles (09/2020 - 11/2018)
2.	Di Lazzaro, Vincenzo: 2 articles (09/2020 - 11/2018)
3.	Lanzone, Jacopo: 2 articles (09/2020 - 11/2018)
4.	Ricci, Lorenzo: 2 articles (09/2020 - 11/2018)
5.	Tombini, Mario: 2 articles (09/2020 - 11/2018)
6.	Ebert, Anne: 2 articles (01/2019 - 01/2015)
7.	Gerber, Benjamin: 2 articles (01/2019 - 01/2015)
8.	Griebe, Martin: 2 articles (01/2019 - 01/2015)
9.	Nees, Frauke: 2 articles (01/2019 - 01/2015)
10.	Szabo, Kristina: 2 articles (01/2019 - 01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Transient Global Amnesia:

1.	Anticonvulsants (Antiepileptic Drugs)IBA 01/01/2006 - "These are similar to attacks of transient global amnesia but are more frequent, shorter, accompanied by clear-cut clinical epileptic manifestations, and respond favorably to antiepileptic drug (AED) therapy. " 01/01/1992 - "EAA are similar to the attacks of transient global amnesia (TGA) but are more frequent, shorter, accompanied by clear-cut clinical and electroencephalographic epileptic manifestations, and respond favorably to antiepileptic therapy. "
2.	Brain-Derived Neurotrophic Factor (BDNF)IBA 10/10/2008 - "The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is not significantly correlated to Transient Global Amnesia: preliminary results of an on-going study in Brescia Province, Italy."
3.	technetium Tc 99m bicisate (Neurolite)FDA Link 09/01/2016 - "Transient global amnesia: a study with Tc-99m ECD SPECT shortly after symptom onset and after recovery."
4.	TeaIBA 01/01/2017 - "Diagnostic criteria are available for TEA, and these memory disturbances should not be misdiagnosed with transient global amnesia. " 11/01/1993 - "The anatomical and pathophysiological basis of TEA is presumed to be similar to transient global amnesia (TGA), that is, it is likely to be primarily hippocampal in origin, but with more variable involvement of limbic and adjacent temporal lobe neocortical structures." 11/29/2022 - "Transient epileptic amnesia (TEA) is a rare cause of acute amnestic syndromes (AAS), often misdiagnosed as transient global amnesia (TGA). " 09/06/2020 - "Transient epileptic amnesia (TEA) is a rare epileptic condition, often confused with transient global amnesia (TGA). " 11/01/2018 - "Transient epileptic amnesia (TEA) is an underestimated condition in emergency clinical setting, where most of transient amnesic episodes tend to be classified as transient global amnesia (TGA). "
5.	Sildenafil Citrate (Viagra)FDA Link 03/01/2020 - "Transient global amnesia (TGA) has been proposed as a possible adverse effect of sildenafil. " 03/01/2020 - "Positive Magnetic Resonance Imaging Evidence of Transient Global Amnesia Following the Use of Sildenafil." 04/01/2019 - "Transient global amnesia associated with sildenafil use. " 07/16/2014 - "[Transient global amnesia associated to sildenafil and sexual activity]." 09/01/2006 - "[Two cases of transient global amnesia (TGA) following sildenafil use]."
6.	Clioquinol (Vioform)FDA Link 12/01/2010 - "Clioquinol (CQ) was associated with cases of transient global amnesia and with the neurodegenerative syndrome subacute myelo-optico-neuropathy (SMON) in humans. " 01/01/1984 - "Transient global amnesia due to clioquinol." 12/01/1979 - "Transient global amnesia after clioquinol: five personal observations from outside Japan." 12/01/1979 - "The clinical aspect closely resembled classical transient global amnesia but the episode after clioquinol lasted longer (24 hours to three days) and a more or less extensive retrograde amnesia persisted permanently. "
7.	Hydrocortisone (Cortisol)FDA LinkGeneric 05/01/2020 - "Transient global amnesia (TGA) can be triggered by a high level of blood cortisol. " 05/01/2020 - "Serum cortisol levels in patients with a transient global amnesia." 01/01/2019 - "Enhanced cortisol secretion in acute transient global amnesia." 01/01/2015 - "Stronger pharmacological cortisol suppression and anticipatory cortisol stress response in transient global amnesia."
8.	Heparin (Liquaemin)FDA LinkGeneric 05/01/2010 - "A 57-year-old man developed transient global amnesia within an hour of bolus unfractionated heparin administration on day 4 post-mitral valve replacement. " 07/01/2010 - "Comments on: Transient global amnesia as the presenting feature of heparin-induced thrombocytopenia." 05/01/2010 - "Transient global amnesia as the presenting feature of heparin-induced thrombocytopenia." 11/01/1994 - "Transient global amnesia associated with acute heparin-induced thrombocytopenia."
9.	BenzodiazepinesIBA 05/01/2002 - "Is transient global amnesia related to endogenous benzodiazepines?" 09/01/1990 - "Benzodiazepine derivates can cause transient global amnesia even when administered in therapeutical doses. " 05/01/1989 - "Alcoholic blackout, benzodiazepine-induced amnesia and transient global amnesia are three disorders that result in acute transient memory loss. "
10.	Tadalafil (Cialis)FDA Link 01/01/2010 - "Tadalafil-induced transient global amnesia." 06/14/2008 - "[Transient global amnesia after tadalafil use]." 07/01/2005 - "We describe a patient who had a transient global amnesia (TGA) after his first-ever use of tadalafil, a potent PDE-5 inhibitor. " 07/01/2005 - "Transient global amnesia after intake of tadalafil, a PDE-5 inhibitor: a possible association?"

Therapies and Procedures

1.	Therapeutics 01/01/2018 - "We performed PubMed searches using the keyword "transient global amnesia" combined with "procedure," "test," "therapy," or various other individual medical procedures. " 01/01/2006 - "These are similar to attacks of transient global amnesia but are more frequent, shorter, accompanied by clear-cut clinical epileptic manifestations, and respond favorably to antiepileptic drug (AED) therapy. " 01/01/1992 - "EAA are similar to the attacks of transient global amnesia (TGA) but are more frequent, shorter, accompanied by clear-cut clinical and electroencephalographic epileptic manifestations, and respond favorably to antiepileptic therapy. "
2.	General Anesthesia 09/01/2005 - "Transient global amnesia after general anesthesia." 04/01/1998 - "[Transient global amnesia after general anesthesia]." 06/01/1985 - "Transient global amnesia following general anesthesia." 07/01/2012 - "We report an incident of probable transient global amnesia in a patient after endoscopic retrograde cholangiopancreatogram under general anesthesia, which was successfully treated with flumazenil. "
3.	Photochemotherapy (Photodynamic Therapy) 01/01/2016 - "Comment on 'Transient memory impairment and transient global amnesia induced by photodynamic therapy'." 11/01/2015 - "Transient memory impairment and transient global amnesia induced by photodynamic therapy."
4.	Intravitreal Injections 08/01/2009 - "Transient global amnesia following intravitreal injection of bevacizumab."
5.	Deep Brain Stimulation 01/01/2013 - "Transient global amnesia associated with accidental high-frequency stimulation of the right hippocampus in deep brain stimulation for segmental dystonia." 01/01/2013 - "We report on a 66-year-old woman with segmental dystonia treated with chronic bilateral deep brain stimulation of the globus pallidus internus, in whom accidental high-voltage, high-frequency stimulation induced an episode of transient global amnesia (TGA) via an electrode contact which was misplaced in the right hippocampus. "