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Caspase 1 (ICE Protease)

A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.
Also Known As:
ICE Protease; CASP1 Caspase; IL-1 beta Convertase; IL1BC Enzyme; Interleukin-1 Converting Enzyme; Pro-Caspase-1; Procaspase-1; Caspase, CASP1; Convertase, IL-1 beta; Converting Enzyme, Interleukin-1; Converting Enzyme, Interleukin-1beta; IL 1 beta Convertase; IL 1 beta Converting Enzyme; Interleukin 1 Converting Enzyme; Interleukin 1beta Converting Enzyme; Pro Caspase 1; Procaspase 1; beta Convertase, IL-1; beta-Converting Enzyme, IL-1; IL-1 beta-Converting Enzyme; Interleukin-1beta Converting Enzyme
Networked: 989 relevant articles (50 outcomes, 86 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Wang, Hong: 9 articles (01/2022 - 04/2015)
2. Kanneganti, Thirumala-Devi: 9 articles (01/2016 - 12/2008)
3. Netea, Mihai G: 8 articles (01/2016 - 12/2009)
4. Jiang, Xiaohua: 7 articles (01/2022 - 04/2015)
5. Roghani, Mehrdad: 6 articles (10/2022 - 04/2019)
6. Shao, Ying: 6 articles (01/2022 - 04/2015)
7. Sun, Yu: 6 articles (01/2022 - 10/2017)
8. Yang, Xiaofeng: 6 articles (01/2022 - 01/2016)
9. Zhang, Yu: 6 articles (01/2022 - 12/2003)
10. Choi, Eric T: 6 articles (11/2021 - 04/2015)

Related Diseases

1. Inflammation (Inflammations)
2. Neuroinflammatory Diseases
3. Infections
4. Asthma (Bronchial Asthma)
5. Infarction (Infarctions)

Related Drugs and Biologics

1. Inflammasomes
2. Proteins (Proteins, Gene)
3. Interleukin-18 (Interleukin 18)
4. Cytokines
5. NLR Proteins
6. Caspase 1 (ICE Protease)
7. morin
8. Ice
9. Interleukins
10. Nucleotides

Related Therapies and Procedures

1. Therapeutics
2. Cardiopulmonary Resuscitation (CPR)
3. Electroacupuncture
4. Resuscitation
5. Chinese Traditional Medicine (Traditional Chinese Medicine)