Putaminal Hemorrhage

Intracranial bleeding into the PUTAMEN, a BASAL GANGLIA nucleus. This is associated with HYPERTENSION and lipohyalinosis of small blood vessels in the putamen. Clinical manifestations vary with the size of hemorrhage, but include HEMIPARESIS; HEADACHE; and alterations of consciousness.

Also Known As:

Networked: 54 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hematoma
2.	Hemiplegia (Spastic Hemiplegia)
3.	Stroke (Strokes)
4.	Hemorrhage
5.	Poisoning

Experts

1.	Maeshima, Shinichiro: 3 articles (06/2021 - 02/2016)
2.	Sonoda, Shigeru: 3 articles (06/2021 - 02/2016)
3.	Okamoto, Sayaka: 2 articles (06/2021 - 02/2016)
4.	Okazaki, Hideto: 2 articles (06/2021 - 02/2016)
5.	Cho, Der-Yang: 2 articles (12/2010 - 08/2005)
6.	Ramnarayan, R: 2 articles (02/2009 - 01/2009)
7.	Chen, Pei-Ya: 1 article (03/2022)
8.	Hsu, Hsien-Ta: 1 article (03/2022)
9.	Hsu, Po-Jen: 1 article (03/2022)
10.	Lin, Shinn-Kuang: 1 article (03/2022)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Putaminal Hemorrhage:

1.	PH.3IBA 02/01/2006 - "The purpose of this study was to compare the performance differences in the Wisconsin Card Sorting Test (WCST) between 55 patients with putaminal hemorrhage (PH) 3 months after stroke and 69 age-matched normal controls. "
2.	XenonIBA 03/01/1988 - "Seventeen separate xenon-enhanced computed tomographic images were performed in seven patients with hypertensive putaminal hemorrhage. " 12/01/1986 - "Regional cerebral blood flow (rCBF) during hypertension and hypercapnia was studied in 33 patients with putaminal hemorrhage, using a single photon emission CT by means of Xenon 133 inhalation method. " 01/01/1996 - "Hemodynamics of hypertensive putaminal hemorrhage evaluated by Xenon-enhanced computed tomography and acetazolamide test."
3.	Methanol (Carbinol)IBA 10/01/2013 - "Clinicians should have high index of suspicion for putaminal hemorrhage when patients with recent methanol intoxication present with altered mental status." 10/01/2013 - "Bilateral putaminal hemorrhage is an uncommon but serious complication in methanol intoxication. " 10/01/2013 - "We report a case of severe methanol intoxication with bilateral putaminal hemorrhage, an uncommon serious complication. " 09/01/1995 - "A case of acute methanol intoxication is presented, in which bilateral putaminal hemorrhage developed after hemodialysis. " 09/01/1995 - "Bilateral putaminal hemorrhage related to methanol poisoning: a complication of hemodialysis? "
4.	ElementsIBA 02/01/1994 - "The distortion and stress distribution in the brain caused by putaminal hemorrhage were estimated by computer stimulation using the finite element method (FEM). " 11/01/1991 - "Deformation and stress distribution caused by putaminal hemorrhage in two-dimensional model brain were analyzed by computer simulation using finite element method. " 11/01/1991 - "[Deformation of brain and stress distribution caused by putaminal hemorrhage--numerical computer simulation by finite element method]."
5.	Triglycerides (Triacylglycerol)IBA 01/01/2023 - "Multivariate logistic regression analyses revealed that for thalamic hemorrhage, ≥200 mmHg systolic blood pressure (p = 0.031), bleeding <15 mL (p = 0.001), and higher modified Rankin scale (mRS) score ≥ 4 at discharge (p = 0.006) were significant variables in the late period (2013-2021) versus the early period (2004-2012), whereas for putaminal hemorrhage, significant factors in the late period were triglyceride <150 mg/dL (p = 0.006) and mRS score ≥ 4 at discharge (p = 0.002). "
6.	SteroidsIBA 02/01/2009 - "This case is presented to show that in a postpartum patient, if she presents with putaminal hematoma, postpartum angiopathy needs to be suspected and appropriate investigations and treatment, including steroids, should be given as the overall prognosis is good."
7.	Stainless Steel (Steel, Stainless)IBA 08/01/2005 - "A unique method of evacuation of hypertensive putaminal hemorrhage (HPH) using a stainless steel tube as a corridor under the assistance of a rigid endoscope is described. "
8.	Phenylpropanolamine (Dexatrim)FDA Link 12/01/1996 - "We report three women aged 33, 63 and 43 years old receiving an anorexigenic medication that contained phenylpropanolamine who, 30 min to 3 h after the ingestion of this medication, presented a frontal hematoma, a left putaminal hematoma and a subaracnoidal hemorrhage, respectively. "
9.	LigandsIBA 09/01/1998 - "A reduced accumulation of these ligands was found in the area surrounding the complete infarction and in the cortex remote from putaminal hemorrhage, indicating the existence of neuron specific injury not visualized by CT and MR. "
10.	Glucose (Dextrose)FDA LinkGeneric 03/02/2022 - "Significant predictors of death due to lobar/putaminal hemorrhage were age, glucose and creatinine levels, initial Glasgow Coma Scale (GCS) score, ICH volume, and presence of intraventricular hemorrhage. "

Therapies and Procedures

1.	Conservative Treatment 06/01/2002 - "He was diagnosed as left putaminal hemorrhage and his symptoms improved by conservative treatment. " 01/01/1989 - "Although there are claims of the superiority of surgery from the standpoint of integrated cortical function following mild putaminal hemorrhage, the results of this investigation indicate that conservative therapy is adequate in such cases, based on improvement in CBF." 08/01/1986 - "At 6 months after surgical treatment, the percentages of patients who returned to full-time work or independent life without disability or with minimal disability (good recovery) were 40% in grade 1, 30% in grade 2, 22% in grade 3, 11% in grade 4, and 0% in grade 5; after conservative treatment, percentages with good recovery were 77% in grade 1, 56% in grade 2, 29% in grade 3, 7% in grade 4, and 0% in grade 5. This study shows that surgical treatment does not give better results in the management of hypertensive putaminal hemorrhage." 01/01/2016 - "We investigated difference of injury of the corticospinal tract (CST) according to surgical or conservative treatment in patients with putaminal hemorrhage (PH), using diffusion tensor tractography (DTT). " 01/01/2016 - "Difference of injury of the corticospinal tract according to surgical or conservative treatment in patients with putaminal hemorrhage."
2.	Activities of Daily Living (ADL) 03/01/1994 - "This study was designed to investigate the sequential changes of the CBF in hypertensive putaminal hemorrhage and to attempt to correlate these data with the treatment and ADL. " 10/01/1986 - "Since CT was introduced, 355 cases of putaminal hemorrhage were experienced and surgical indication was evaluated in relation to long-term outcome (ADL). " 07/01/1983 - "Seventy-four patients with hypertensive putaminal hemorrhage (HPH) were followed at least 6 months after treatment and estimated by ADL. " 09/01/2004 - "Impact of stereotactic hematoma evacuation on activities of daily living during the chronic period following spontaneous putaminal hemorrhage: a randomized study." 09/01/2020 - "Influence of hematoma volume and age on cognitive functions and ADL after putaminal hemorrhage."
3.	Craniotomy 05/01/2007 - "Comparison of CT-guided aspiration to key hole craniotomy in the surgical treatment of spontaneous putaminal hemorrhage: a prospective randomized study." 01/01/2022 - "A 61-year-old man with a history of craniotomy for the left putaminal hemorrhage at the age of 50 fell from a bed, bruised his head, and lost consciousness. " 07/01/2017 - "A 68-year-old male patient who had a history of left putaminal hemorrhage treated with a craniotomy was diagnosed with a tentorial dAVF on a magnetic resonance angiogram. " 10/01/1990 - "He had undergone a craniotomy for hypertensive right putaminal hemorrhage 4 months previously. " 10/01/1988 - "Comparison of stereotactic aspiration, craniotomy, and conservative treatment for putaminal hemorrhage."
4.	Therapeutics 10/01/1990 - "These results suggest that current medical and neurosurgical therapies remain ineffective in preventing the devastating neurologic consequences of hypertensive putaminal hemorrhage." 06/01/2021 - "This study aims to investigate the relationship between several types of putaminal hemorrhage and walking independence and orthotic therapy in patients with hemiplegia. " 05/15/2009 - "A multivariate analysis using the logistic regression model showed that antithrombotic therapy was an independent factor for cerebellar hemorrhage (OR 3.66, 95%CI 1.31-10.18), lobar hemorrhage (OR 2.27, 95%CI 1.12-4.57), and thalamic hemorrhage (OR 2.20, 95%CI 1.06-4.54) in comparison to putaminal hemorrhage. " 06/01/2021 - "The relationship between the types of hematomas and walking independence and orthotic therapy in patients with hemiplegia with putaminal hemorrhage was also analyzed. " 01/01/1994 - "We concluded that high COP therapy for 2 weeks following hematoma removal was effective to suppress and/or reduce brain edema associated with putaminal hemorrhage, and that this therapy could be continued for 2 weeks without systemic complications."
5.	Decompressive Craniectomy 01/01/2009 - "In all, 23 patients with putaminal hematoma who underwent decompressive craniectomy in the last 4 years were analyzed. " 09/01/2011 - "In this study, a comparison of motor recovery on hypertensive putaminal hematoma (HPH) with 30 mL or more has been made between conventional treatment and decompressive craniectomy (DC) combined with electroacupuncture (EA). "