Basal Ganglia Hemorrhage

Bleeding within the subcortical regions of cerebral hemispheres (BASAL GANGLIA). It is often associated with HYPERTENSION or ARTERIOVENOUS MALFORMATIONS. Clinical manifestations may include HEADACHE; DYSKINESIAS; and HEMIPARESIS.

Also Known As:

Networked: 22 relevant articles (0 outcomes, 3 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Hematoma
2.	Hemorrhage
3.	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
4.	Dyskinesias (Dyskinesia)
5.	Postoperative Hemorrhage

Experts

1.	Dong, Xiao-Qiao: 2 articles (08/2010 - 06/2010)
2.	Zhang, Zu-Yong: 2 articles (08/2010 - 06/2010)
3.	Hu, Yue-Yu: 2 articles (08/2010 - 06/2010)
4.	Yu, Wen-Hua: 2 articles (08/2010 - 06/2010)
5.	Ma, Bu-Qing: 1 article (01/2015)
6.	Zhang, Mao: 1 article (01/2015)
7.	Ba, Li: 1 article (01/2015)
8.	Wu, Dan: 1 article (01/2015)
9.	Yin, Xiao-Ping: 1 article (01/2015)
10.	Zhou, Jun: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Basal Ganglia Hemorrhage:

1.	XenonIBA 01/01/2008 - "Xenon-CT study of regional cerebral blood flow around hematoma in patients with basal ganglia hemorrhage." 01/01/2008 - "Xenon-CT was performed on 15 patients with basal ganglia hemorrhage and hematoma volume < 50 mL. rCBF was measured within 36 h of onset and an average of 13 days later by 27-pixel rings in perihematomal area and its enantiomorph in contralateral hemisphere. " 05/17/2004 - "Xenon-CT was performed on 5 patients of basal ganglia hemorrhage with the hematoma volume less than 30 ml, 3 males and 2 females, aged 56.8 +/- 5.6. "
2.	Tissue Plasminogen Activator (Alteplase)FDA Link 11/01/2010 - "Although several neurosurgical trials have failed to demonstrate benefit for surgical evacuation of sICH, multiple research trials are ongoing investigating acute blood pressure control, deep or basal ganglionic hemorrhage evacuation via minimally invasive approach (MISTIE; http://mistietrial.com/default.aspx), lobar ICH evacuation (STICH; II http://research.ncl.ac.uk/stich/), and intraventricular thrombolysis with tissue plasminogen activator (tPA) (CLEAR III; http://biosgroup-johnshopkinsmedicine.health.officelive.com/default.aspx)."
3.	Nicotinamide PhosphoribosyltransferaseIBA 01/01/2013 - "High concentrations of visfatin in the peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome." 10/21/2013 - "Admission plasma visfatin level strongly correlates with hematoma growth and early neurologic deterioration in patients with acute spontaneous basal ganglia hemorrhage."
4.	ResistinIBA 06/01/2010 - "High concentrations of resistin in the peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome." 01/01/2012 - "Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with C-reactive protein in Chinese Han patients with spontaneous basal ganglia hemorrhage."
5.	LeptinIBA 05/01/2013 - "In 50 healthy controls and 92 patients with acute spontaneous basal ganglia hemorrhage presenting to the emergency department of a large primary care hospital, we measured plasma leptin levels using an enzyme-linked immunosorbent assay in a blinded fashion. " 08/01/2010 - "Time course of plasma leptin concentrations after acute spontaneous basal ganglia hemorrhage."
6.	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 01/15/2015 - "Plasma pituitary adenylate cyclase-activating polypeptide concentrations and mortality after acute spontaneous basal ganglia hemorrhage."
7.	Warfarin (Coumadin)FDA LinkGeneric 05/29/2012 - "GCS<8, age over 70 years, intraventricular and basal ganglia hemorrhage, coumadin medication, combination of co-morbidities, hypertensive hemorrhage and postoperative re-bleeding were statistically significant risk factors for worse outcome (GOS 1 and 2) in the operated group. "
8.	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/01/2015 - "There were a total of 90 rats with basal ganglia hemorrhage, which were randomly divided into the following four groups: ICH (Sprague-Dawley rats with autologous femoral arterial blood injection into the basal ganglia), sulforaphane (SFN) (SFN was intraperitoneally administered into rats), retinoic acid (RA) (RA was intraperitoneally administered into rats), and dimethyl sulfoxide (the rats were treated with dimethyl sulfoxide). "
9.	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/01/2015 - "There were a total of 90 rats with basal ganglia hemorrhage, which were randomly divided into the following four groups: ICH (Sprague-Dawley rats with autologous femoral arterial blood injection into the basal ganglia), sulforaphane (SFN) (SFN was intraperitoneally administered into rats), retinoic acid (RA) (RA was intraperitoneally administered into rats), and dimethyl sulfoxide (the rats were treated with dimethyl sulfoxide). "
10.	Carbon MonoxideIBA 05/29/2012 - "GCS<8, age over 70 years, intraventricular and basal ganglia hemorrhage, coumadin medication, combination of co-morbidities, hypertensive hemorrhage and postoperative re-bleeding were statistically significant risk factors for worse outcome (GOS 1 and 2) in the operated group. "

Therapies and Procedures

1.	Catheters 01/01/2014 - "The present study aims to evaluate the efficacy and safety of NE approach using an adjustable cannula to treat basal ganglia hemorrhage. " 01/01/2014 - "Endoscopic evacuation of basal ganglia hemorrhage via keyhole approach using an adjustable cannula in comparison with craniotomy."
2.	Craniotomy 01/01/2010 - "Retrospective analysis of database of 44 patients undergoing craniotomy for hypertensive basal ganglia hemorrhage between December 2002 and May 2007. " 06/01/2006 - "Endoscopic surgery for spontaneous basal ganglia hemorrhage: comparing endoscopic surgery, stereotactic aspiration, and craniotomy in noncomatose patients." 01/01/2014 - "Endoscopic evacuation of basal ganglia hemorrhage via keyhole approach using an adjustable cannula in comparison with craniotomy." 01/01/2013 - "Transfusion of previously frozen apheresis platelets reduces the rate of postoperative hemorrhage, average postoperative hemorrhage volume, disability rate, and mortality rate in ASA-sensitive patients with acute hypertensive basal ganglia hemorrhage undergoing craniotomy." 01/01/2013 - "The authors evaluated the effects of acetylsalicylic acid (ASA) usage and transfusion of previously frozen apheresis platelets on postoperative hemorrhage, activities of daily living (ADL) score, and mortality rate in patients with acute hypertensive basal ganglia hemorrhage undergoing craniotomy. "
3.	Decompressive Craniectomy 07/01/2010 - "We conducted a retrospective study to assess the effect of decompressive craniectomy on outcome of patients with spontaneous basal ganglia hemorrhage (SBH). " 07/01/2010 - "Decompressive craniectomy in addition to hematoma evacuation improves mortality of patients with spontaneous basal ganglia hemorrhage."
4.	Angioplasty (Angioplasty, Transluminal) 08/01/2006 - "We describe a patient who experienced a fatal ipsilateral basal ganglia hemorrhage within an hour after carotid angioplasty and stent placement. "
5.	Thrombolytic Therapy 04/01/2008 - "Influence of intraventricular fibrinolytic therapy with rt-PA on the long-term outcome of treated patients with spontaneous basal ganglia hemorrhage: a case-control study."