Hydrogels

Water swollen, rigid, 3-dimensional network of cross-linked, hydrophilic macromolecules, 20-95% water. They are used in paints, printing inks, foodstuffs, pharmaceuticals, and cosmetics. (Grant & Hackh's Chemical Dictionary, 5th ed)

Also Known As:

Networked: 11591 relevant articles (1101 outcomes, 1884 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Tabata, Yasuhiko: 78 articles (12/2021 - 07/2002)
2.	Burdick, Jason A: 40 articles (06/2022 - 01/2009)
3.	Li, Yang: 28 articles (09/2022 - 08/2011)
4.	Liu, Yang: 28 articles (06/2022 - 10/2011)
5.	Kong, Deling: 28 articles (05/2022 - 01/2012)
6.	Shoichet, Molly S: 26 articles (10/2022 - 06/2004)
7.	Zhang, Yu: 26 articles (03/2022 - 12/2009)
8.	Wu, Jun: 25 articles (08/2022 - 01/2011)
9.	Cui, Wenguo: 23 articles (01/2023 - 01/2016)
10.	Fan, Daidi: 22 articles (11/2022 - 03/2014)

Related Diseases

1.	Wounds and Injuries (Trauma) 01/01/2004 - "This paper examines reports in the literature on the outcomes of studies into the efficacy of this group of dressings, discusses the types of wounds that are most suitable for hydrogel application and poses questions that merit further investigation." 04/23/2023 - "One of the most advanced, promising, and commercially viable research issues in the world of hydrogel dressing is gaining functionality to achieve improved therapeutic impact or even intelligent wound repair. " 09/01/2021 - "The novel hydrogel shows promising results as a candidate for future wound treatment, likely to be highly effective even in the case of biofilm-complicating infected wounds." 07/01/2019 - "Therefore, designing a wound dressing patch using a biodegradable hydrogel, which can provide a sustained release/delivery of active agents that can support cell proliferation and cell migration, will be highly beneficial for promoting diabetic wound healing. " 07/01/2015 - "Future Direction: Studies that investigate the efficacy of antimicrobial hydrogel wound dressings on both in vivo and in vitro biofilms are important. "
2.	Neoplasms (Cancer) 11/15/2022 - "It is anticipated that the local drug release method and environment-responsive benefits of smart hydrogels will offer a novel technique for the low-toxicity and highly effective treatment of oral malignancy." 10/17/2022 - "The release results demonstrated that the macroporous pH-sensitive hydrogels loaded with DOX could release 98.7% of DOX at pH 5.0, which would be highly beneficial for the release of anti-cancer drugs in the environment of cancer cells. " 11/17/2022 - "In vitro cytotoxicity studies indicated excellent biocompatibility of the supramolecular hydrogel matrix, whereas the DOX/8HQ-Glu-loaded supramolecular hydrogel showed a sustained inhibition efficacy against cancer cells. " 01/01/2020 - "A sufficient dose shifts toward the surface of the head model and is located only in the lesion site, demonstrating that TPU-PAAm hydrogel can provide an optimal dose distribution and be clinically effective for treating superficial tumors. " 01/01/2018 - "Furthermore, MRD hydrogel can activate dendritic cells of draining lymph nodes, specifically deplete M2-like tumor-associated macrophages (TAMs), and produce active, cytotoxic T cells to further defend the cells against remaining tumors, providing potent anticancer efficacy against subcutaneous and metastatic tumors in vivo. "
3.	Inflammation (Inflammations) 02/01/2022 - "The proposed self-healing hydrogel antiadhesion barrier with MMP-2-responsive drug release behavior is highly effective for decreasing inflammation and inhibiting tendon adhesion. " 12/01/2021 - "All the fabricated hydrogels dramatically reduced the elevated inflammation and apoptosis indices of the SCI-inflicted rats (p ≤ 0.05). " 11/01/2022 - "The present study an improved the effective topical drug-delivery system by CHO/Aloe hydrogel with the potential to reduce inflammation over time, allowing the body to recover more quickly and better re-epithelialization for improving the wound-healing procedures." 01/01/2019 - "In vivo experiments revealed that the hydrogels are effective in the control of inflammation and regeneration of the periodontium. " 09/01/2020 - "However, both types of loaded hydrogels accelerated inflammation resolution and improved the epithelialization process, while showing a neodermal thickness similar to that of nondiabetic animals. "
4.	Burns 01/01/2022 - "This study aimed to investigate whether MAE-loaded PVA/PET hydrogels have protective effects against burn wound healing. " 01/01/2012 - "The present study substantiates the potential efficacy of honey hydrogel dressings in accelerating burn wound healing." 08/01/2016 - "A randomized clinical trial study was conducted to compare the efficacy of hydrogel produced by the radiation application research center (Yazd Branch) with MaxGel and routine dressing on burn repair in the Yazd Burn hospital. " 01/01/2020 - "Finally, the wound healing efficacy of hydrogel in skin burn model showed dermal appendages and similar epidermis, dermis and stratum corneum to the commercial reference. " 01/01/2013 - "Bilayer hydrogel with autologous stem cells derived from debrided human burn skin for improved skin regeneration."
5.	Infections 09/01/2019 - "Most importantly, the hydrogel coatings reveal excellent antimicrobial efficacy with a log reduction above 5 in a rodent subcutaneous infection model. " 04/13/2023 - "Photodynamic inactivation hydrogel proved to be effective for decolonization of human skin including the potential to act against superficial skin infections. " 12/01/2014 - "Hence, it was clear that the developed hydrogels can be used effectively for preventing and treating infections." 01/01/2022 - "One-stage revision THA with antibacterial hydrogel coated implants represents a safe and effective procedure providing infection eradication and satisfying subjective functional outcomes in selected patients." 01/01/2022 - "We conclude that the PF hydrogel biofilm model is a new platform that will facilitate progress in future biofilm investigations, as well as studies of the efficacy of new potential medicine against biofilm infections."

Related Drugs and Biologics

1.	Hydrogels
2.	Collagen
3.	Chitosan
4.	Gelatin
5.	Alginates
6.	Hyaluronic Acid (Hyaluronan)
7.	Solutions
8.	Peptides (Polypeptides)
9.	Anti-Bacterial Agents (Antibiotics)
10.	Silicones

Related Therapies and Procedures

1.	Injections
2.	Therapeutics
3.	Microspheres (Microsphere)
4.	Drug Therapy (Chemotherapy)
5.	Contact Lenses