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Genetic Predisposition to Disease (Genetic Predisposition)

A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Also Known As:
Genetic Predisposition; Genetic Susceptibility; Genetic Predispositions; Predisposition, Genetic; Susceptibility, Genetic; Genetic Susceptibilities; Predispositions, Genetic; Susceptibilities, Genetic
Networked: 7652 relevant articles (83 outcomes, 1008 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Hypertension (High Blood Pressure)
3. Lung Neoplasms (Lung Cancer)
4. Genetic Predisposition to Disease (Genetic Predisposition)
5. Weight Loss (Weight Reduction)

Experts

1. Taioli, Emanuela: 23 articles (02/2020 - 08/2002)
2. Wu, Xifeng: 17 articles (01/2017 - 08/2002)
3. Granados, Julio: 16 articles (08/2021 - 01/2003)
4. Wang, Wei: 16 articles (01/2021 - 09/2008)
5. Larsson, Susanna C: 15 articles (01/2022 - 07/2017)
6. Brennan, Paul: 15 articles (10/2021 - 08/2002)
7. Vargas-Alarcón, Gilberto: 15 articles (01/2018 - 01/2003)
8. Qi, Lu: 14 articles (10/2022 - 03/2012)
9. Rothman, Nathaniel: 12 articles (10/2021 - 04/2005)
10. Zhang, Zhengdong: 12 articles (01/2021 - 06/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Genetic Predisposition to Disease:
1. Biomarkers (Surrogate Marker)IBA
2. LipidsIBA
3. AllergensIBA
4. Inosine Triphosphate (ITP)IBA
5. CalciumIBA
6. VaccinesIBA
7. Immunoglobulin G (IgG)IBA
8. Transaminases (Aminotransferases)IBA
9. Proteins (Proteins, Gene)FDA Link
10. CytokinesIBA

Therapies and Procedures

1. Therapeutics
03/01/2001 - "Physicians will become mentors and counselors, advising patients on the best treatment path given their unique genetic predisposition--even in this sophisticated, high tech field, the physician-patient relationship is likely to improve, highlighted by individualized therapies and personal attention."
09/01/2012 - "However, because of the high remission rates and long-term overall survival achieved with current APL treatments, late complications related to antileukemic therapy should be taken into account, giving priority to efficacy agents with the lowest potential of leukemogenesis, despite individual genetic susceptibilities that are not well known. "
07/24/2023 - "Human genetics studies have now associated hundreds of thousands of differences in our DNA sequence ("genomic variation") with disease risk and other phenotypes, many of which could reveal novel mechanisms of human biology and uncover the basis of genetic predispositions to diseases, thereby guiding the development of new diagnostics and therapeutics. "
01/01/2023 - "Studies have shown that mitochondrial therapeutics may have the potential to slow the progression of POAG by protecting against mitochondrial decline associated with age, genetic susceptibility, and other pathology. "
12/25/2022 - "Liver preneoplastic and neoplastic lesions of the genetically susceptible F344 and resistant BN rats cluster, respectively, with human HCC with better (HCCB) and poorer prognosis (HCCP); therefore, they represent a valid model to study the molecular alterations determining the genetic predisposition to HCC and the response to therapy. "
2. Glycemic Control
3. Drug Therapy (Chemotherapy)
4. Precision Medicine
5. Chemoprevention