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Amphetamine-Related Disorders (Addiction, Amphetamine)

Subscribe to New Research on Amphetamine-Related Disorders

Disorders related or resulting from use of amphetamines.

Also Known As:

Addiction, Amphetamine; Abuse, Amphetamine; Amphetamine Related Disorders; Dependence, Amphetamine; Disorder, Amphetamine-Related; Disorders, Amphetamine-Related; Amphetamine Abuse; Amphetamine Addiction; Amphetamine Dependence

Networked: 132 relevant articles (9 outcomes, 19 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Cocaine-Related Disorders (Cocaine Addiction)
2.	Tachycardia (Tachyarrhythmias)
3.	Cardiomyopathies (Cardiomyopathy)
4.	Hypertension (High Blood Pressure)
5.	Arteritis

Experts

1.	Franck, Johan: 9 articles (03/2014 - 12/2004)
2.	Jayaram-Lindström, Nitya: 8 articles (03/2014 - 12/2004)
3.	Beck, Olof: 5 articles (03/2014 - 01/2005)
4.	de Wit, Harriet: 3 articles (08/2015 - 10/2009)
5.	Tiihonen, Jari: 3 articles (05/2014 - 01/2007)
6.	Föhr, Jaana: 3 articles (05/2014 - 01/2007)
7.	Konstenius, Maija: 3 articles (03/2014 - 07/2008)
8.	Hammarberg, Anders: 3 articles (01/2010 - 07/2008)
9.	Hart, Amy B: 2 articles (08/2015 - 01/2012)
10.	Kauhanen, Jussi: 2 articles (05/2014 - 01/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Amphetamine-Related Disorders:

1.	Methylphenidate (Ritalin)FDA LinkGeneric 01/01/2007 - "Methylphenidate is an effective treatment for reducing intravenous drug use in patients with severe amphetamine dependence." 04/01/2010 - "The study was a double-blind, placebo controlled trial with parallel groups design comparing the efficacy of a fixed dose (72mg) of OROS methylphenidate (MPH) with placebo (PL) in reducing ADHD symptoms in currently abstinent adults with amphetamine dependence and ADHD. " 01/01/2006 - "Cerebral vasculitis associated with amphetamine abuse is well documented, and in rare cases ischaemic stroke has been reported after methylphenidate intake in children. " 01/01/2007 - "Individuals meeting DSM-IV criteria for intravenous amphetamine dependence (N=53) were randomly assigned to receive aripiprazole (15 mg/day), slow-release methylphenidate (54 mg/day), or placebo for 20 weeks. " 01/01/2007 - "A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence."
2.	Phencyclidine (Angel Dust)IBA 05/01/2005 - "Further testing will be required to verify the efficacy of the test in populations with a higher prevalence of phencyclidine and amphetamine abuse." 01/01/1986 - "Open clinical trials have suggested that desipramine may be an effective agent for treatment of phencyclidine (PCP) or amphetamine dependence. " 01/01/1986 - "Double-blind comparison of desipramine and placebo for treatment of phencyclidine or amphetamine dependence."
3.	Naltrexone (ReVia)FDA LinkGeneric 11/01/2008 - "Naltrexone for the treatment of amphetamine dependence: a randomized, placebo-controlled trial." 11/01/2008 - "Eighty patients who met DSM-IV criteria for amphetamine dependence were randomized to 12 weeks of double-blind naltrexone (50 mg) or placebo treatment. " 07/01/2008 - "The potential of naltrexone as an adjunct pharmaceutical for amphetamine dependence is promising." 01/01/2005 - "An open clinical trial of naltrexone for amphetamine dependence: compliance and tolerability." 12/01/2004 - "The potential of naltrexone as an adjunct pharmaceutical for the treatment of amphetamine dependence is promising and needs to be investigated further."
4.	Amphetamine (Amfetamine)FDA LinkGeneric 01/01/2011 - "This study showed that NTX attenuates drug- and cue-induced locomotor behavior in amphetamine-conditioned animals, supporting recent clinical findings that indicated a potential role of NTX as a treatment for amphetamine dependence." 11/01/2000 - "The study of the effects of repeated amphetamine administration and withdrawal on brain reward function has relevance to both amphetamine dependence and non-drug-induced depressions. " 08/01/2013 - "Taking into account the positive correlation between amphetamine withdrawal-induced anxiety and relapse to amphetamine taking, our results suggest that modulation of mGluRs may prevent relapse to amphetamine and might pose a new direction in amphetamine abuse therapy." 01/01/2013 - "The development of amphetamine dependence largely depends on the effects of amphetamine in the brain reward systems. " 08/01/2012 - "Vulnerability to sensitization of frequency-modulated 50-kHz vocalization response of Sprague-Dawley rats to amphetamine, which supposedly reflects rats' propensity for amphetamine dependence, shows large inter-individual diversity. "
5.	Cocaine (Cocaine HCl)IBA 12/01/1999 - "Although no new medications are approved for cocaine and amphetamine abuse, a variety of candidate treatments have shown promise in ongoing studies. " 04/01/2014 - "The present results suggest that ED patients with a history of cocaine or amphetamine abuse represent a sub-population of patients with lasting dysfunctional mood modulatory mechanisms." 04/01/2014 - "Mixed Models analyses showed that a significant effect on EES total score variation was found for cocaine or amphetamine abuse (b = .25; p < .01). " 04/01/2014 - "To estimate the global prevalence of cocaine and amphetamine dependence and the burden of disease attributable to these disorders. " 10/01/2013 - "Androgenic anabolic steroid, cocaine and amphetamine abuse and adverse cardiovascular effects."
6.	Heroin (Diamorphine)IBA 05/01/2012 - "Sustained-release opiate blockers for treating heroin and amphetamine dependence." 09/01/2005 - "Indicator data were examined by age group on the number of persons entering treatment for heroin and amphetamine dependence, arrests for heroin use/possession and number of drug related deaths in NSW, Australia. " 01/01/1995 - "It seems that amphetamine abuse plays only a minor role with heroin users. " 01/01/1973 - "An outbreak of intravenous amphetamine abuse in heroin addicts." 01/01/2013 - "The objective of this study was to examine the trend in characteristics of clients seeking treatment for buprenorphine abuse and compare them to those seeking treatment for heroin and amphetamine abuse. "
7.	Desipramine (Pertofrane)FDA LinkGeneric 01/01/1986 - "Open clinical trials have suggested that desipramine may be an effective agent for treatment of phencyclidine (PCP) or amphetamine dependence. " 01/01/1986 - "Although desipramine clearly was no more effective than placebo in treatment of PCP dependence, subjects with amphetamine dependence who received desipramine remained in treatment longer and submitted more urine samples absent of amphetamine than did subjects who received placebo." 01/01/1986 - "Double-blind comparison of desipramine and placebo for treatment of phencyclidine or amphetamine dependence." 04/01/1983 - "Cocaine and amphetamine dependence treated with desipramine." 01/01/2001 - "It shows that fluoxetine, amlodipine, imipramine and desipramine have very limited benefits for amphetamine dependence and abuse. "
8.	Carbon MonoxideIBA 01/01/2010 - "Amphetamine dependence and co-morbid alcohol abuse: associations to brain cortical thickness." 06/01/2009 - "In this study, we report the case of a patient with adult ADHD with co-morbid amphetamine abuse who was treated successfully with the non-stimulant alertness-promoting drug modafinil. " 03/01/2014 - "To test the efficacy and safety of osmotic release oral system (OROS) methylphenidate (MPH) in doses up to 180 mg/day to treat attention deficit hyperactivity disorder (ADHD) and prevent any drug relapse in individuals with a co-diagnosis of ADHD and amphetamine dependence. "
9.	modafinil (armodafinil)FDA Link 06/01/2009 - "Modafinil treatment of amphetamine abuse in adult ADHD." 11/01/2002 - "Modafinil for social phobia and amphetamine dependence." 06/01/2009 - "In this study, we report the case of a patient with adult ADHD with co-morbid amphetamine abuse who was treated successfully with the non-stimulant alertness-promoting drug modafinil. " 07/30/2007 - "Modafinil is a mild psychostimulant used for the treatment of sleep and arousal-related disorders, and has been considered a pharmacotherapy for cocaine and amphetamine dependence; however, modafinil's mechanism of action is largely unclear. "
10.	Opioid Receptors (Opioid Receptor)IBA 02/01/2011 - "Preclinical studies and, more recently, human studies, suggest that the opioid receptor antagonist, naltrexone, might be useful in the treatment of amphetamine abuse. "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 01/01/2007 - "To date, evidence on the effectiveness of psychosocial treatments has remained modest, and no pharmacotherapy has proven effective for amphetamine dependence. " 07/01/2003 - "The results of these studies might guide the development of a pharmacotherapy for the treatment of amphetamine abuse/dependence." 11/01/2008 - "Currently there is no approved pharmacotherapy for amphetamine dependence. " 09/15/2006 - "Despite increased reports of amphetamine abuse and dependence, a putative pharmacotherapy has yet to be identified. " 01/01/2005 - "In conclusion, naltrexone was well tolerated with moderate rates of compliance, supporting the feasibility of investigating this compound in a larger placebo-controlled trial as a potential pharmacotherapy for amphetamine dependence."
2.	Neurosurgical Procedures 11/01/1979 - "A case of unsuspected acute amphetamine abuse by a 22-year-old girl which led to serious intracranial hypertension during anaesthesia for a neurosurgical procedure is described. "
3.	Obstetrical Analgesia 01/01/1988 - "Our purpose was to investigate whether obstetric analgesia, particularly by nitrous oxide, constitutes a risk that the infant might develop amphetamine addiction in later life. "
4.	Transplantation (Transplant Recipients) 01/01/2006 - "Conditions that amplify sympathetic bias such as stress, smoking, amphetamine abuse, HIV, heart failure, and transplantation may accelerate wrinkling. "
5.	Nebulizers and Vaporizers (Inhaler) 01/01/1987 - "A 19-year-old man with a history of intravenous cocaine and amphetamine abuse injected 1.1 mg of epinephrine intravenously from an over-the-counter bronchodilator inhaler. "