Stereotypic Movement Disorder

Motor behavior that is repetitive, often seemingly driven, and nonfunctional. This behavior markedly interferes with normal activities or results in severe bodily self-injury. The behavior is not due to the direct physiological effects of a substance or a general medical condition. (DSM-IV, 1994)

Also Known As:

Networked: 17 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Seizures (Seizure)
2.	Body Weight (Weight, Body)
3.	Mitochondrial Diseases (Mitochondrial Disease)
4.	Dyskinesias (Dyskinesia)
5.	Night Terrors (Sleep Terror)

Experts

1.	Walkinshaw, Malcolm D: 2 articles (09/2015 - 09/2014)
2.	Erman, Burak: 1 article (09/2015)
3.	Taylor, Paul: 1 article (09/2015)
4.	Naithani, Ankita: 1 article (09/2015)
5.	Michels, Paul A M: 1 article (09/2014)
6.	Zhong, Wenhe: 1 article (09/2014)
7.	McNae, Iain W: 1 article (09/2014)
8.	Fothergill-Gilmore, Linda A: 1 article (09/2014)
9.	Morgan, Hugh P: 1 article (09/2014)
10.	Bax, Ad: 1 article (09/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Stereotypic Movement Disorder:

1.	Opioid Receptors (Opioid Receptor)IBA 06/01/2002 - "The aim of this study was to use fentanyl-induced prolactin response as an opiate receptor sensitivity test in patients with stereotypic movement disorder (SMD) manifesting SIB (skin picking). "
2.	ProlactinIBA 06/01/2002 - "The aim of this study was to use fentanyl-induced prolactin response as an opiate receptor sensitivity test in patients with stereotypic movement disorder (SMD) manifesting SIB (skin picking). "
3.	Fentanyl (Sublimaze)FDA LinkGeneric 06/01/2002 - "The aim of this study was to use fentanyl-induced prolactin response as an opiate receptor sensitivity test in patients with stereotypic movement disorder (SMD) manifesting SIB (skin picking). "
4.	artemetherFDA Link 09/01/1994 - "Further studies in Sprague-Dawley rats using IM administration of AE and artemether (AM) at a dose of 12.5-50 mg/kg/day for 28 days confirmed the onset of a clinical neurologic syndrome with dose-related changes in body weight, activity, and seizure-like activity, stereotypic movement disorders, and ECG changes.(ABSTRACT TRUNCATED AT 250 WORDS)"
5.	Citalopram (Escitalopram)FDA Link 05/01/2000 - "Citalopram for head-banging." 06/01/2009 - "Escitalopram treatment of stereotypic movement disorder in an adolescent with mitochondrial disorder and mental retardation."
6.	Naltrexone (ReVia)FDA LinkGeneric 09/01/1998 - "He reported a sense of pleasure from his head-banging, and the frequency of this behavior decreased when he was treated with the opioid antagonist naltrexone. " 07/01/1994 - "During naltrexone administration, there were fewer days with frequent head-banging and self-biting, whereas there were more days on which blows to the head or self-biting were infrequent. "
7.	Protein Subunits (Protein Subunit)IBA 09/15/2015 - "Analysis of the rigid body motions over the trajectory highlights the concerted anticorrelated rigid body rocking motion of the four protomers, which drives the T to R transition. "
8.	Fluvoxamine (Luvox)FDA LinkGeneric 05/01/1997 - "To describe the effects of treatment with the selective serotonin reuptake inhibitor fluvoxamine on three patients with advanced dementia who developed a stereotypic movement disorder. "
9.	Serotonin (5 Hydroxytryptamine)IBA 05/01/1997 - "To describe the effects of treatment with the selective serotonin reuptake inhibitor fluvoxamine on three patients with advanced dementia who developed a stereotypic movement disorder. "
10.	Pyruvate KinaseIBA 09/01/2014 - "The transition between the inactive T-state (apoenzyme) and active R-state (effector bound enzyme) of Trypanosoma cruzi pyruvate kinase (PYK) is accompanied by a symmetrical 8° rigid body rocking motion of the A- and C-domain cores in each of the four subunits, coupled with the formation of additional salt bridges across two of the four subunit interfaces. "