HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Propylene Glycol (1,2 Propanediol)

Subscribe to New Research on Propylene Glycol

A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.

Also Known As:

1,2 Propanediol; Propan-1,2-Diol; Propylene Glycol Monohydrate; Propylene Glycol Sodium Salt; Propylene Glycol, (+-)-Isomer; Propylene Glycol, (R)-Isomer; Propylene Glycol, (S)-Isomer; Glycol, Propylene; Monohydrate, Propylene Glycol; 1,2-Propanediol

Networked: 382 relevant articles (24 outcomes, 42 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58
- Alcohols: 387
  - Glycols: 31
    - Propylene Glycols: 2
      - Propylene Glycol: 382

Experts

1.	Choi, Han-Gon: 3 articles (11/2015 - 05/2006)
2.	Kraut, Jeffrey A: 3 articles (01/2015 - 01/2008)
3.	Riker, Richard R: 3 articles (07/2009 - 01/2002)
4.	Fraser, Gilles L: 3 articles (07/2009 - 01/2002)
5.	Fowler, Joseph F: 3 articles (01/2009 - 09/2007)
6.	Yong, Chul Soon: 2 articles (11/2015 - 09/2006)
7.	Arunakaran, J: 2 articles (10/2014 - 08/2014)
8.	Sharmila, G: 2 articles (10/2014 - 08/2014)
9.	Rensfeldt, Kjell: 2 articles (10/2014 - 09/2012)
10.	McArt, J A A: 2 articles (05/2012 - 12/2011)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/1990 - "The effect of a liposomal preparation of beta-methasone dipropionate (0.039%, BDP) has been compared to that of a commercial propylene glycol-gel containing 0.064% BDP in a double-blind, randomized, paired trial lasting 14 d in 10 patients with atopic eczema and 10 patients with psoriasis vulgaris. " 01/01/1981 - "The efficacy and safety of betamethasone dipropionate, 0.05% in a propylene glycol base (Diprolene), was investigated in an open, fixed-dose study of thirty-one patients with resistant psoriasis. " 01/01/1981 - "The effects of increased penetration of betamethasone dipropionate in a propylene glycol base (Diprolene) for psoriasis." 12/01/1967 - "[Treatment of psoriasis of the scalp and skin folds with a fluocinolone-propylene glycol combination]." 02/01/2014 - "Tacrolimus-loaded LCNs are more effective in the treatment of psoriasis-like skin inflammation as compared to tacrolimus dissolved in propylene glycol. "
2.	Infection 04/30/1964 - "THE INFLUENCE OF PROPYLENE GLYCOL ON THE GROWTH OF HISTOPLASMA CAPSULATUM IN VITRO AND IN EXPERIMENTAL INFECTION." 05/01/1951 - "[Experimental Mycobacterium tuberculosis infection of the guinea pig after contact with propylene glycol]." 07/01/1946 - "Use of propylene glycol and other glycol vapors as means of air sterilization for control of air-borne infections." 12/26/1941 - "THE PROTECTION OF MICE AGAINST INFECTION WITH AIR-BORNE INFLUENZA VIRUS BY MEANS OF PROPYLENE GLYCOL VAPOR." 01/01/1984 - "Treatment of dermatophyte infections in HPPK with 50% propylene glycol in distilled water gave poor results but when 1% econazole nitrate was added negative cultures were found in 86.4% of the patients treated for 3 weeks."
3.	Seborrheic Dermatitis 07/01/1988 - "Propylene glycol in the treatment of seborrheic dermatitis of the scalp: a double-blind study." 01/18/1964 - "Forty-eight infants with seborrhea capitis were treated with a preparation containing a polypeptide-fatty acid complex and tyrothricin in a propylene glycol vehicle, to determine if this material was non-toxic and if it was effective in the treatment of infantile seborrheic dermatitis. " 07/01/1988 - "Thirty-nine patients with seborrheic dermatitis of the scalp were treated in a double-blind controlled study with a solution containing either 15 percent propylene glycol, 50 percent ethanol, and 35 percent water, or a solution containing 50 percent ethanol and 50 percent water. " 07/01/1988 - "This propylene-glycol-containing solution was easy to apply, cosmetically attractive, and may be an alternative to corticosteroids for the treatment of seborrheic dermatitis of the scalp." 07/01/1967 - "Management of seborrhea capitis with fluocinolone acetonide in propylene glycol: a clinical report."
4.	Neoplasms (Cancer) 05/01/1987 - "The corresponding tumor incidences in the propylene glycol instilled solvent control females were 26, 0 and 0%, whereas in the males of this group they were 22, 0 and 0%, respectively. " 01/01/1981 - "In the propylene glycol injected control groups, the corresponding tumor incidences were 28 and 0% in females and 32 and 0% in males. " 09/14/2006 - "The clotrimazole-loaded suppository with P 188 and propylene glycol could not irritate or damage the rectal tissues of rats and gave the improved anti-tumor activity in a dose-dependent manner at mouse. " 10/01/2014 - "Sprague-Dawley male rats were divided into four groups, Group I: vehicle control (propylene glycol), Group II: chemically induced cancer model (MNU + T); Group III: chemically induced cancer model + quercetin (200 mg per kg b.w.); Group IV: quercetin (200 mg per kg b.w.). " 10/01/1980 - "A formulation of 1-[2-chloroethyl-U-14C]-3-cyclohexyl-1-nitrosourea in ethanol:propylene glycol (1:4, v/v) was administered to rats previously infiltrated with RT6 glioma tumors (astrocytic series); the organ and tumor tissue distribution was followed at 1, 4, 12, and 24 hr postinjection. "
5.	Dermatitis 10/01/1994 - "Future studies on propylene glycol dermatitis should include repeated patch tests with serial dose dilutions, repeated open application tests/provocative use tests, oral challenge tests, and biopsies for a more complete evaluation of mechanisms and clinical significance." 01/01/2010 - "Propylene glycol dermatitis in the printing industry: the fundamental role of a workplace visit." 10/01/1994 - "Evaluation of dermatitis associated with propylene glycol application or ingestion remains a challenge. " 10/01/1994 - "Propylene glycol dermatitis: re-evaluation of an old problem." 01/01/1991 - "Propylene glycol dermatitis."

Related Drugs and Biologics

1.	Dimethyl Sulfoxide (DMSO)
2.	Acyclovir (Aciclovir)
3.	Ethanol (Ethyl Alcohol)
4.	Polyethylene Glycols (Polyethylene Glycol)
5.	Glycerol (Glycerine)
6.	Fluorouracil (Carac)
7.	laurocapram (Azone)
8.	Trifluridine (Viroptic)
9.	Acetone
10.	Minoxidil (Rogaine)

Related Therapies and Procedures

1.	Oral Administration
2.	Ligation
3.	Radiotherapy
4.	Middle Ear Ventilation (Tympanostomy)
5.	Electrocoagulation (Electrocautery)