Cochlear Implantation

Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.

Also Known As:

Cochlear Implantations; Cochlear Prosthesis Implantations; Implantation, Cochlear; Implantation, Cochlear Prosthesis; Implantations, Cochlear; Implantations, Cochlear Prosthesis; Prosthesis Implantation, Cochlear; Prosthesis Implantations, Cochlear; Cochlear Prosthesis Implantation

Networked: 2768 relevant articles (182 outcomes, 374 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913
- Prosthesis Implantation: 268
  - Cochlear Implantation: 2768
- Otorhinolaryngologic Surgical Procedures: 2
  - Otologic Surgical Procedures: 8
    - Cochlear Implantation: 2768

Experts

1.	Lenarz, Thomas: 32 articles (08/2021 - 11/2002)
2.	Roland, J Thomas: 26 articles (11/2021 - 08/2006)
3.	Carlson, Matthew L: 25 articles (01/2022 - 08/2011)
4.	Mylanus, Emmanuel A M: 23 articles (01/2022 - 11/2004)
5.	Sterkers, Olivier: 23 articles (07/2021 - 01/2007)
6.	Van de Heyning, Paul: 19 articles (05/2022 - 09/2008)
7.	Buchman, Craig A: 18 articles (10/2021 - 08/2004)
8.	Grolman, Wilko: 18 articles (01/2021 - 09/2010)
9.	Papsin, Blake C: 18 articles (01/2021 - 02/2003)
10.	Kameswaran, Mohan: 17 articles (05/2022 - 09/2007)

Related Diseases

1.	Hearing Loss (Hearing Impairment) 08/01/2023 - "Understanding the causes of a hearing loss (HL) predict the outcome of cochlear implantation and is of great importance in understanding the mechanism of the disease and in providing the best treatment. " 08/01/2012 - "Cochlear implantation was successful at rehabilitating the hearing loss with the child able to continue mainstream education, with her academic performance and speech discrimination both showing marked improvement. " 07/01/2010 - "Considering that 26 percent of infants with bilateral moderate to severe hearing loss showed improvement in one year, habilitation protocols, especially very early cochlear implantation within one year of birth, should be reconsidered." 11/24/2023 - "Cochlear implantation was considered a good treatment for profound hearing loss due to idiopathic HP, which provides a reference for patients to receive timely and correct treatment." 04/01/2023 - "Evidence suggests that Cochlear Implantation (CI) is a beneficial approach for auditory and speech skills improvement in children with severe to profound hearing loss. "
2.	Deafness (Deaf Mutism) 06/01/2017 - "One year after cochlear implantation, most patients with single-sided deafness showed benefits in hearing as measured by validated questionnaires However, not all patients reported a significant improvement in general quality of life. " 01/01/2022 - "This is important to better understand the influence of CH on CI outcomes, and to assess the safety and efficacy of future novel treatments for deafness that will be administered as adjunctive therapies to cochlear implantation. " 01/01/2020 - "For those with single-sided deafness in whom cochlear implantation is contraindicated, bone-conduction implants when compared with no intervention provide clinically important functional gains in hearing thresholds (36-41 dB improvement in pure tone audiometry and 38-56 dB improvement in speech reception threshold, P < .05; GRADE: Moderate) and improve speech perception in noise (signal-to-noise ratio -2.0 vs. 0.6, P < .05 for active percutaneous devices; signal-to-noise ratio improved by 1.3-2.5 dB, P < .05 for active transcutaneous devices; GRADE: Moderate) and hearing-specific quality of life (Abbreviated Profile for Hearing Aid Benefit, ease of communication: 12%-53% vs. 24%-59%; background noise: 18%-48% vs. 33%-79%; listening in reverberant condition: 26%-55% vs. 41%-65%, P < .05 [active percutaneous devices]; ease of communication: 7% vs. 20%; background noise: 46% vs. 69%; listening in reverberant condition: 27% vs. 43%; P < .05 [active transcutaneous devices]; Children's Home Inventory for Listening Difficulties score 7.3 vs. 3.4; P < .05 [passive transcutaneous devices]; GRADE: Moderate). " 02/01/2016 - "Although there were marked variations in the outcome of cochlear implantation, patients with specific deafness gene mutations showed relatively good results. " 02/01/2008 - "Based on the results, our objective is to determine the efficacy of the two applications of cochlear implantation, the first characterized by a shallow electrode insertion and preservation of low-frequency natural hearing for partial deafness, and the second characterized by a very deep electrode insertion used in subjects with severe to profound deafness. "
3.	Sensorineural Hearing Loss 04/18/2022 - "Cochlear implantation is considered the best treatment option for patients with severe-to-profound sensorineural hearing loss for whom conventional hearing aids are insufficient. " 01/12/2021 - "Cochlear implantation is currently the most effective treatment for patients with severe-to-profound sensorineural hearing loss. " 07/01/2017 - "Cochlear implantation (CI) is the most important and effective treatment for patients with profound sensorineural hearing loss. " 04/01/2000 - "Multielectrode cochlear implantation is the most effective treatment for profound sensorineural hearing loss. " 01/01/2016 - "Cochlear implantation (CI) has proven to be an effective treatment for severe bilateral sensorineural hearing loss (SNHL). "
4.	Tinnitus 09/01/2023 - "Patients with higher THI and VAS scores had a larger decline and the highest benefits in terms of tinnitus handicap improvement. The study findings demonstrate that the majority of patients with moderate to profound SNHL eligible for cochlear implantation benefit from complete or partial tinnitus suppression and improved quality of life after implantation." 03/01/2021 - "The meta-analysis identifies statistically significant benefits in cochlear implantation for sound localization, tinnitus suppression, in global quality of life assessment and in 2 of the 3 subscales of quality of life assessment (ease of communication and reverberation). " 01/01/2018 - "Those experiencing noticeable tinnitus may benefit more from cochlear implantation than those without; subjective tinnitus reduction may be correlated with improved sound localization and speech recognition in noise. " 03/01/1994 - "After cochlear implantation, tinnitus was abolished in 44% and decreased in 39%, for an overall improvement in 83%. " 11/01/2021 - "After cochlear implantation, the patient demonstrated improved speech perception on the implanted side and decreased tinnitus within 1 month of activation. "
5.	Otosclerosis 03/01/2015 - "Although cochlear implantation gives better overall results, stapedotomy with hearing aids can still be very effective in the management of patients with far-advanced otosclerosis. " 01/01/2017 - "Emerging evidence supports the efficacy of direct acoustic cochlear implantation in patients with advanced otosclerosis whose needs cannot be managed using the combination of stapes surgery and hearing aids. " 01/01/2023 - "Comparison of the efficacy of cochlear implantation and stapes surgery in far advanced otosclerosis: a meta-analysis study." 01/01/2023 - "The aim of the study was to measure the distance of the tympanic nerve to the oval window and round window niche in adult cadavers for evaluating its usability as an anatomical landmark during middle ear-related surgeries, including stapedotomy and cochleostomy, and for preventing its iatrogenic damage during surgical practices such as otosclerosis surgery and cochlear implantation. " 01/01/2023 - "This study is to compare the hearing outcomes and complications of stapes surgery and cochlear implantation (CI) in patients with far-advanced otosclerosis (FAO). "

Related Drugs and Biologics

1.	Silver Sulfadiazine (SSD)
2.	Mitochondrial DNA (mtDNA)
3.	Dexamethasone (Maxidex)
4.	Steroids
5.	Interleukin 1 Receptor Antagonist Protein (Anakinra)
6.	Monoamine Oxidase (MAO)
7.	Ciprofloxacin (Cipro)
8.	Biomarkers (Surrogate Marker)
9.	Capsules (Microcapsules)
10.	Platinum

Related Therapies and Procedures

1.	Hearing Aids (Hearing Aid)
2.	Therapeutics
3.	Cochlear Implants (Cochlear Implant)
4.	Electrodes (Electrode)
5.	Stapes Surgery (Stapedectomy)