Ethylene Glycol (Monoethylene Glycol)

A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.

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Networked: 1451 relevant articles (48 outcomes, 149 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kataoka, Kazunori: 12 articles (09/2014 - 12/2003)
2.	McMartin, Kenneth E: 12 articles (05/2014 - 10/2004)
3.	Wang, Jun: 11 articles (12/2015 - 04/2011)
4.	Nishiyama, Nobuhiro: 11 articles (07/2014 - 12/2003)
5.	Chen, Xuesi: 10 articles (01/2016 - 05/2009)
6.	Kwon, Glen S: 9 articles (08/2014 - 05/2005)
7.	Tang, Zhaohui: 8 articles (01/2016 - 11/2012)
8.	Wei, Yuquan: 7 articles (01/2014 - 04/2011)
9.	Bae, You Han: 7 articles (10/2011 - 02/2004)
10.	Lu, Weiyue: 6 articles (06/2015 - 04/2010)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2000 - "Efficient clearance of poly(ethylene glycol)-modified immunoenzyme with anti-PEG monoclonal antibody for prodrug cancer therapy." 02/01/2015 - "Effects of poly(ethylene glycol) grafting density on the tumor targeting efficacy of nanoparticles with ligand modification." 07/01/2015 - "Polymeric nanoparticles have been widely used as nano-drug delivery systems in preclinical and clinical trials for cancer therapy, and these systems usually need to be sterically stabilized by poly(ethylene glycol) (PEG) to maintain stability and avoid rapid clearance by the immune system. " 01/01/2012 - "The present studies noninvasively investigate the passive tumor distribution potential of a series of poly(ethylene glycol) (PEG) nanocarriers using a SkinSkan spectrofluorometer and an In Vivo Imaging System (IVIS) 100. " 12/09/2015 - "After forming the micelleplex delivery system, the corresponding nanoparticles (Dm-NP) might undergo several modifications as follows: (i) a poly(ethylene glycol) (PEG) corona, which is stable in the circulatory system and protects nanovectors from RES clearance; (ii) a pHe responsive linkage breakage, which induces PEG detachment at tumor sites and thereby facilitates cell targeting; and (iii) a cell-penetration peptide, which is exposed upon the removal of PEG and further enhances cellular uptake. "
2.	Poisoning 03/01/2007 - "Successful therapy of paediatric ethylene glycol poisoning: a case report and annual survey by a regional poison centre." 03/18/1999 - "New treatment for ethylene glycol poisoning." 01/01/2013 - "The main objective of this study is an analysis of clinical features and identification of prognostic factors in poisoning with ethylene glycol of patients hospitalized in the Toxicology Unit in the years 2000-2009. " 07/01/2011 - "Studies on ethylene glycol poisoning: one patient - 154 admissions." 07/01/2011 - "We undertook this investigation to evaluate our incidence of EG poisoning during the timeframe of before the first report linking a death to ethylene glycol to shortly after the first murder trial. "
3.	Urolithiasis 05/01/2014 - "pinnatum is effective in prevention and treatment of ethylene glycol-induced urolithiasis." 07/01/2012 - "This study was designed to evaluate the effects of Solanum xanthocarpum fruit extract in ethylene-glycol-induced urolithiasis in the male Wistar rats. " 07/01/2015 - "Urolithiasis was induced by ethylene glycol (EG) in Wistar rats. " 01/01/2015 - "Urolithiasis was induced by ethylene glycol (% 0.75) in drinking water. " 01/01/2014 - "Rat model of urolithiasis was established by administering 0.75% ethylene glycol (EG) in drinking water, and the effects of a homeopathic preparation of B. "
4.	Nephrolithiasis 01/01/2015 - "Protective effects of the aqueous extract of Crocus sativus against ethylene glycol induced nephrolithiasis in rats." 07/01/2015 - "The efficacy of antioxidant therapy against oxidative stress and androgen rise in ethylene glycol induced nephrolithiasis in Wistar rats." 01/01/2015 - "The potential effects of Fa extract on the prevention and treatment of CaOx nephrolithiasis were analyzed in an ethylene glycol- (EG-) induced CaOx crystallization model in rats and an in vitro assay. " 01/01/2015 - "To evaluate the preventive effect of hydro-alcoholic extract of Dolichos biflorus seeds (DBE) in ethylene glycol induced nephrolithiasis. " 12/01/2014 - "on ethylene glycol (EG)-induced nephrolithiasis in rats. "
5.	Carcinoma (Carcinomatosis) 10/09/2008 - "Furthermore, the ethylene glycol chain at the meta position exhibits a superior efficacy that leads to the permanent ablation of human breast carcinoma (MDA-MB-231) in nude mice. " 08/15/2012 - "Among the nine conjugate ensemble, derivative 21, bearing a robust triazole ring connected to ethylene glycol units by an amide function and showing excellent cell sensitivity properties, was selected for in vivo studies in an ovarian carcinoma model xenografted in immunodeficient mice. " 06/07/2012 - "DOX-FA-SNs showed a higher cytotoxicity in human cervical carcinoma cells (HeLa cells) than DOX loaded carboxyl (-COOH) and poly(ethylene glycol) (PEG) modified SNs (DOX-COOH-SNs and DOX-PEG-SNs, respectively). " 08/01/2002 - "Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethylene glycol) conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells." 11/01/2015 - "Preparation, Characterization, and In Vivo Study of 7-Ethyl-14-Aminocamptothecin-Loaded Poly(Ethylene Glycol)2000 -Poly(Lactic Acid)2000 Polymeric Micelles Against H460 Human Nonsmall Cell Lung Carcinoma."

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3.	Micelles
4.	Folic Acid (Vitamin M)
5.	Methanol (Carbinol)
6.	Calcium Oxalate
7.	Doxorubicin (Adriamycin)
8.	poly(lactide) (polylactide)
9.	Chitosan
10.	Gelatin

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Lasers (Laser)
3.	Drug Therapy (Chemotherapy)
4.	Immunotherapy
5.	Electrodes (Electrode)