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Miller Fisher Syndrome (Fisher Syndrome)

A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)
Also Known As:
Fisher Syndrome; Syndrome, Miller Fisher; Guillain-Barre Syndrome, Miller Fisher Variant; Miller Fisher Variant of Guillain Barre Syndrome; Miller-Fisher Syndrome; Syndrome, Fisher; Syndrome, Miller-Fisher; Guillain Barre Syndrome, Miller Fisher Variant; Ophthalmoplegia, Ataxia and Areflexia Syndrome
Networked: 433 relevant articles (12 outcomes, 26 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Guillain-Barre Syndrome
2. COVID-19
3. Encephalitis (Encephalitis, Rasmussen)
4. Ophthalmoplegia (External Ophthalmoplegia)
5. Ataxia (Dyssynergia)

Experts

1. Yuki, Nobuhiro: 32 articles (01/2017 - 12/2002)
2. Kusunoki, Susumu: 19 articles (01/2021 - 01/2003)
3. Willison, Hugh J: 17 articles (01/2019 - 04/2002)
4. Yuki, N: 14 articles (02/2016 - 04/2000)
5. Hirata, Koichi: 12 articles (05/2013 - 04/2003)
6. Koga, Michiaki: 12 articles (05/2013 - 07/2003)
7. Plomp, Jaap J: 9 articles (09/2008 - 04/2002)
8. Hirata, K: 9 articles (05/2008 - 05/2000)
9. Kaida, Kenichi: 7 articles (01/2021 - 06/2010)
10. Jacobs, Bart C: 7 articles (01/2019 - 04/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Miller Fisher Syndrome:
1. Intravenous Immunoglobulins (IVIG)FDA Link
2. AntibodiesIBA
3. GangliosidesIBA
4. SteroidsIBA
5. Immunoglobulin G (IgG)IBA
6. AutoantibodiesIBA
7. AntigensIBA
8. GQ1b gangliosideIBA
9. Adrenal Cortex Hormones (Corticosteroids)IBA
10. Antihypertensive Agents (Antihypertensives)IBA

Therapies and Procedures

1. Therapeutics
2. Plasma Exchange
3. Immunotherapy
4. Plasmapheresis
5. Transcranial Magnetic Stimulation