1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)

11/01/2006 - "Dose dependent inhibitory effect of dietary caraway on 1,2-dimethylhydrazine induced colonic aberrant crypt foci and bacterial enzyme activity in rats."
12/01/2005 - "The number of colorectal aberrant crypt foci (ACF), putative preneoplastic lesions induced by 1,2-dimethylhydrazine, was reduced after MDT-1 administration (10(9) cfu/dose, 3 times/wk for 4 wk). "
01/01/2000 - "Inhibition by ginseng of 1,2-dimethylhydrazine induction of aberrant crypt foci in the rat colon."
11/01/1997 - "Inhibition of development of N,N'-dimethylhydrazine-induced rat colonic aberrant crypt foci by pre, post and simultaneous treatments with 24R,25-dihydroxyvitamin D3."
02/26/1997 - "Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats."

06/01/2012 - "High fat mixed lipid diet modifies protective effects of exercise on 1,2 dimethylhydrazine induced colon cancer in rats."
08/01/2005 - "Chemopreventive efficacy of ginger, a naturally occurring anticarcinogen during the initiation, post-initiation stages of 1,2 dimethylhydrazine-induced colon cancer."
11/01/1992 - "In a series of experiments, we used the 1,2-dimethylhydrazine animal model of colonic cancer in conjunction with these drugs, to study the effect on the development of colon cancer. "
09/01/2015 - "Induction of Colon Cancer in Mice with 1,2-Dimethylhydrazine."
06/01/2007 - "Onopordum cynarocephalum induces apoptosis and protects against 1,2 dimethylhydrazine-induced colon cancer."

01/01/2007 - "In another study in rats, however, red chile pepper in the diet at the same dose decreased the number of tumors seen with 1,2-dimethylhydrazine. "
07/15/1986 - "Gut-associated lymphoid tissue and 1,2-dimethylhydrazine intestinal tumors in the rat: an histological and immunoenzymatic study."
04/01/1984 - "The proposed experimental protocol can be applied to study the relationship between fat intake, bile acid fecal excretion and tumor yield in experimental colonic tumorigenesis initiated by 1,2-dimethyl-hydrazine."
10/01/1981 - "The synthetic compound 1,2-dimethylhydrazine is employed in carcinogenesis studies because of its reliable and specific ability to produce colon tumors in rodents. "
11/01/1980 - "The dosage of 1,2-dimethylhydrazine used in this study is the lowest single oral dose of this carcinogen reported to induce colon tumors."

06/01/2013 - "Male Sprague-Dawley rats were administered with a colon-specific pro-carcinogen, 1,2-dimethylhydrazine dihydrochloride to achieve the early stages of colorectal cancer. "
10/01/2010 - "Early stages of colorectal cancer were produced in rats with 1,2-dimethylhydrazine dihydrochloride. "
06/01/2003 - "High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine."
03/01/2001 - "Effect of bacterial metabolism in the intestine on colorectal tumors induced by 1,2-dimethylhydrazine in transgenic mice harboring human prototype c-Ha-ras genes."
04/01/1998 - "Effect of mouse intestinal bacteria on incidence of colorectal tumors induced by 1,2-dimethylhydrazine injection in gnotobiotic transgenic mice harboring human prototype c-Ha-ras genes."

11/01/1997 - "In the present study, colon adenocarcinomas were induced by 1,2-dimethylhydrazine treatment in rats. "
11/01/2007 - "Here, we performed genome-wide scanning of male (ACI/SegHsd x Wistar-Furth)F2 (AWF2) rats to map susceptibility genes influencing the evolution of early colorectal lesions to adenocarcinoma following 1,2-dimethylhydrazine administration. "
12/01/1998 - "The REG and PRO cell clones were obtained from a colon adenocarcinoma induced in a BDIX rat by 1,2-dimethylhydrazine. "
09/01/1993 - "Fischer F344 rats receiving 20mg/kg of 1,2-dimethylhydrazine per week for 20 weeks developed adenocarcinoma of the colon. "
01/01/1991 - "A new cell line (RCN-9) was established in culture from a transplantable rat colon adenocarcinoma, which was induced in the colon of a male Fischer F344 rat by subcutaneous administration of 1,2-dimethylhydrazine. "