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Fluorescein (Funduscein)

A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium such as the aqueous humor.
Also Known As:
Funduscein; C.I. 45350; Colircusi Fluoresceina; D & C Yellow No. 7; D & C Yellow No. 8; D and C Yellow No. 7; D and C Yellow No. 8; D&C Yellow No. 7; D&C Yellow No. 8; Diofluor; Disodium Fluorescein; Fluor-I-Strip A.T.; Fluorescein Dipotassium Salt; Fluorescein Disodium Salt; Fluorescein Monosodium Salt; Fluorescite; Fluorescéine sodique Faure; Fluorets; Ful-Glo; Minims Fluorescein Sodium; Minims Fluoresceine; Minims Stains; Optifluor Diba; Uranine; Dipotassium Salt, Fluorescein; Disodium Salt, Fluorescein; Fluor I Strip A.T.; Fluorescein Sodium, Minims; Fluorescein, Disodium; Fluorescein, Sodium; Fluoresceina, Colircusi; Fluoresceine, Minims; Ful Glo; Monosodium Salt, Fluorescein; Sodium, Fluorescein; Fluorescein Sodium; Sodium Fluorescein
Networked: 8604 relevant articles (277 outcomes, 813 trials/studies)

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Drug Context: Research Results

Experts

1. Bandello, Francesco: 38 articles (06/2022 - 05/2006)
2. Yannuzzi, Lawrence A: 38 articles (01/2022 - 01/2002)
3. Querques, Giuseppe: 37 articles (06/2022 - 09/2005)
4. Freund, K Bailey: 33 articles (11/2022 - 08/2002)
5. Shields, Carol L: 31 articles (12/2022 - 06/2003)
6. Tsubota, Kazuo: 31 articles (12/2021 - 06/2003)
7. Souied, Eric H: 29 articles (06/2022 - 03/2003)
8. Spaide, Richard F: 26 articles (03/2021 - 01/2002)
9. Sarraf, David: 24 articles (09/2021 - 10/2008)
10. Herbort, Carl P: 23 articles (06/2021 - 04/2002)

Related Diseases

1. Macular Edema
2. Dry Eye Syndromes (Dry Eye Syndrome)
10/01/2022 - "Dry eye symptoms improved in the population, with both SPEED and OSDI lowering of dry eye symptoms by approximately 35% (P < .001) at month 6. Significant improvements in lissamine green conjunctival staining, corneal fluorescein staining, TBUT, osmolarity, and secreting meibomian glands and meibum quality were also seen. "
07/01/2022 - "Between the groups, there was a significantly better improvement in tear film osmolarity (ANOVA, P<0.001), Lissamine green staining score (ANOVA, P=0.002), corneal fluorescein staining (ANOVA, P=0.011), dry eye symptoms (ANOVA, P=0.040) and Schirmer test scores (ANOVA, P=0.001) with CAs 0.09%. "
07/01/2022 - "Within the groups, there was a significant improvement (ANOVA, P<0.05) in tear film osmolarity, lissamine green staining score, dry eye symptom score, corneal fluorescein staining and Schirmer test scores over 3 months of intervention. "
10/01/2019 - "Breath H2 concentration, fluorescein tear film breakup time (fTBUT), Schirmer's test, 8-OHdG concentration in tears, reported ocular symptoms using the dry eye-related QOL score questionnaire, and the visual analogue scale were assessed at weeks 0 and 3. Change in fTBUT in the H2-producing milk group was significantly greater than that in the placebo group. "
04/01/2013 - "Preoperative and postoperative results in the total sample were also compared; statistically significantly different results were observed in fluorescein break-up time and dry eye symptoms at 1.5 months, which showed improvement thereafter. "
3. Neoplasms (Cancer)
4. Choroidal Neovascularization
5. Lacrimal Apparatus Diseases (Epiphora)

Related Drugs and Biologics

1. Coloring Agents (Dyes)
2. Retinaldehyde (Retinal)
3. Rose Bengal
4. isothiocyanic acid
5. Indocyanine Green (Cardio-Green)
6. 1-phenyl-3,3-dimethyltriazene (PDT)
7. Fluorescein-5-isothiocyanate (FITC)
8. Bevacizumab (Avastin)
9. Dextrans (Dextran)
10. Acids

Related Therapies and Procedures

1. Lasers (Laser)
2. Light Coagulation
3. Therapeutics
4. Photochemotherapy (Photodynamic Therapy)
5. Slit Lamp