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Tetraethylammonium (Tetraethylammonium Bromide)

Subscribe to New Research on Tetraethylammonium

A potassium-selective ion channel blocker. (From J Gen Phys 1994;104(1):173-90)

Also Known As:

Tetraethylammonium Bromide; Tetraethylammonium Iodide; Tetraethylammonium Hydroxide; Bromide, Tetraethylammonium; Chloride, Tetraethylammonium; Hydroxide, Tetraethylammonium; Iodide, Tetraethylammonium; Ion, Tetraethylammonium; Tetraethylammonium Chloride; Tetraethylammonium Ion

Networked: 242 relevant articles (6 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Amines: 1422
  - Quaternary Ammonium Compounds: 1159
    - Tetraethylammonium Compounds
      - Tetraethylammonium: 242
- Onium Compounds
  - Quaternary Ammonium Compounds: 1159
    - Tetraethylammonium Compounds
      - Tetraethylammonium: 242

Experts

1.	Zhao, Lei: 2 articles (12/2011 - 12/2011)
2.	Li, Li: 2 articles (12/2011 - 12/2011)
3.	Cogolludo, Angel L: 2 articles (06/2010 - 04/2010)
4.	Villamor, Eduardo: 2 articles (06/2010 - 04/2010)
5.	Dick, Gregory M: 2 articles (05/2007 - 09/2005)
6.	Gurney, A M: 2 articles (11/2003 - 03/2000)
7.	Osipenko, O N: 2 articles (11/2003 - 03/2000)
8.	Tate, R J: 2 articles (11/2003 - 03/2000)
9.	Hayek, Salim: 1 article (06/2014)
10.	Manatunga, Amita: 1 article (06/2014)

Related Diseases

1.	Ganglion Cysts (Ganglion) 01/01/1953 - "[Studies on the pharmacological effect of quaternary tropeines and tetraethylammonium-like ganglion-blocking agents]." 12/30/1975 - "Tetraethylammonium, in concentrations normally required for ganglion blocking activity, does not influence the ureteral activity, but in higher doses it prolonges the duration of the action potential several times and increases the intraluminal pressure. " 10/01/1961 - "It possesses a transient ganglion blocking action of the tetraethylammonium-type as shown in experiments in which it caused a fall in blood pressure and blocked the response of the nictitating membrane to pre- but not to post-ganglionic stimulation of the cervical sympathetic nerve." 01/01/1985 - "Selective blocking action of tetraethylammonium ion on three types of acetylcholine receptors in Aplysia ganglion cells." 04/01/1978 - "Contractions of the nictitating membrane and postganglionic action potentials evoked by electrical stimulation of the vagal artificial preganglionic trunk in the cross-anastomosed ganglion were blocked by treatment with tetraethylammonium and also with atropine. "
2.	Contracture 01/01/1985 - "The action of intravenous anaesthetic and central depressant drugs on the contractures elicited by tetraethylammonium in the chick biventer cervicis muscle." 01/01/1986 - "Tetraethylammonium-methohexitone induced contractures and miniature end-plate potential discharge in the chick biventer cervicis muscle." 04/01/1985 - "In low concentrations, they increased the amplitude of the indirectly-elicited twitch and tetanic contractions, whereas in high concentrations they reduced the evoked contractions and the contractures produced by depolarizing agents such as acetylcholine or tetraethylammonium. " 01/01/1984 - "The influence of barbiturate drugs on tetraethylammonium induced contractures of the chick biventer cervicis muscle in vitro." 10/01/1982 - "1.--The tetraethylammonium (TEA) effects on K+ contracture and membrane depolarization are compared in both crab and frog skeletal muscle fibres. "
3.	Renal Insufficiency (Renal Failure) 02/01/1984 - "To assess whether the secretory clearance of N1-methylnicotinamide (NMN), an endogenous organic cation, represents renal tubular secretion of the organic cation, the relationship between the secretory clearance of NMN, CLscn(NMN), and that of tetraethylammonium bromide (TEA), CLscn(TEA), was examined in normal and experimental renal failure (ERF) rats. " 01/01/1992 - "We studied the acute effect of methylguanidine (MG), a suspected uremic toxin that accumulates in renal failure, on p-aminohippurate (PAH) and tetraethylammonium (TEA) uptake in rabbit kidney slices, on Na+,K+ ATPase activity in the microsomal fraction of rabbit kidneys, and on transepithelial active Na transport across toad skin. "
4.	Hyperuricemia 03/15/2005 - "Basolateral uptake of p-aminohippurate (PAH) and tetraethylammonium (TEA), and both protein and mRNA levels of rOAT1, rOAT3 and rOCT2 in the kidney gradually improved during 14 days of recovery from hyperuricemia. "
5.	Sepsis (Septicemia) 01/01/1986 - "Tetraethylammonium chloride or other drugs that decrease outward potassium current and prolong the action potential duration may be helpful in treating cardiac dysfunction that accompanies sepsis."

Related Drugs and Biologics

1.	Tea
2.	Potassium
3.	p-Aminohippuric Acid (p-Aminohippurate)
4.	Acetylcholine (Acetylcholine Chloride)
5.	Hexamethonium (Hexamethonium Bromide)
6.	Atropine (Hyoscyamine)
7.	Methohexital (Brevital)
8.	Messenger RNA (mRNA)
9.	Nicotine
10.	Scopolamine (Hyoscine)

Related Therapies and Procedures

1.	Carbohydrate-Restricted Diet (Low Carbohydrate Diet)
2.	Microelectrodes
3.	Sympathectomy (Sympathectomies)
4.	Electrodes (Electrode)
5.	Sodium-Restricted Diet (Diet, Sodium Restricted)