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Topotecan (Hycamtin)

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
Also Known As:
Hycamtin; 9-Dimethylaminomethyl-10-hydroxycamptothecin; Hycamtamine; NSC-609699; Nogitecan Hydrochloride; SK&F-104864-A; SKF-104864-A; Topotecan Hydrochloride; Topotecan Monohydrochloride, (S)-Isomer; 9 Dimethylaminomethyl 10 hydroxycamptothecin; Hydrochloride, Nogitecan; Hydrochloride, Topotecan; NSC 609699; NSC609699; SK&F 104864 A; SK&F104864A; SKF 104864 A; SKF104864A
Networked: 1951 relevant articles (255 outcomes, 738 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Stewart, Clinton F: 30 articles (01/2019 - 03/2002)
2. Pommier, Yves: 23 articles (01/2022 - 08/2002)
3. Abramson, David H: 22 articles (01/2022 - 08/2007)
4. Schaiquevich, Paula: 18 articles (12/2018 - 11/2007)
5. Januchowski, Radosław: 17 articles (05/2022 - 01/2013)
6. Nowicki, Michał: 14 articles (05/2022 - 01/2014)
7. Zabel, Maciej: 14 articles (04/2021 - 07/2012)
8. Coleman, Robert L: 13 articles (11/2020 - 01/2002)
9. Chantada, Guillermo L: 13 articles (10/2017 - 03/2004)
10. Doroshow, James H: 12 articles (10/2019 - 02/2010)

Related Diseases

1. Neoplasms (Cancer)
2. Ovarian Neoplasms (Ovarian Cancer)
3. Small Cell Lung Carcinoma (Small Cell Lung Cancer)
4. Neuroblastoma
5. Retinoblastoma (Glioblastoma, Retinal)

Related Drugs and Biologics

1. Paclitaxel (Taxol)
2. Cisplatin (Platino)
3. Platinum
4. Carboplatin (JM8)
5. Irinotecan (Camptosar)
6. Etoposide (VP 16)
7. Cyclophosphamide (Cytoxan)
8. Topoisomerase I Inhibitors
9. Pharmaceutical Preparations
10. Vincristine (Oncovin)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Radiotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Aftercare (After-Treatment)