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Thrombospondin 1

An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
Also Known As:
TSP-1
Networked: 850 relevant articles (18 outcomes, 133 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lawler, Jack: 29 articles (01/2020 - 01/2002)
2. Masli, Sharmila: 14 articles (05/2022 - 04/2004)
3. Gutierrez, Linda S: 8 articles (01/2021 - 02/2003)
4. Roberts, David D: 8 articles (07/2015 - 12/2007)
5. Martiny, Laurent: 7 articles (01/2021 - 03/2005)
6. Wang, Shuxia: 6 articles (02/2021 - 11/2007)
7. Frangogiannis, Nikolaos G: 6 articles (10/2014 - 06/2005)
8. Tuszynski, George P: 6 articles (01/2010 - 08/2002)
9. Zhang, Wei: 5 articles (01/2022 - 10/2010)
10. Mittal, Vivek: 5 articles (01/2020 - 05/2013)

Related Diseases

1. Neoplasms (Cancer)
2. Thyroid Neoplasms (Thyroid Cancer)
3. Kidney Diseases (Kidney Disease)
4. Fibrosis (Cirrhosis)
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Transforming Growth Factor beta1 (TGF beta 1)
3. Endostatins
4. Intercellular Signaling Peptides and Proteins (Growth Factors)
5. Epidermal Growth Factor (EGF)
6. Collagen
7. Small Interfering RNA (siRNA)
8. Doxorubicin (Adriamycin)
9. Alkalies
10. Leu-Ser-Lys-Leu peptide

Related Therapies and Procedures

1. Therapeutics
2. Radiotherapy
3. Gingivectomy
4. Lasers (Laser)
5. Injections