Knee Replacement Arthroplasty (Total Knee Replacement)

Replacement of the knee joint.

Also Known As:

Total Knee Replacement; Arthroplasty, Replacement, Knee; Arthroplasties, Knee Replacement; Arthroplasties, Replacement, Knee; Arthroplasty, Knee Replacement; Arthroplasty, Replacement, Partial Knee; Knee Arthroplasty; Knee Arthroplasty, Total; Knee Replacement Arthroplasties; Partial Knee Arthroplasty; Partial Knee Replacement; Replacement Arthroplasties, Knee; Replacement Arthroplasty, Knee; Replacement, Total Knee; Unicompartmental Knee Arthroplasty; Unicompartmental Knee Replacement; Unicondylar Knee Arthroplasty; Unicondylar Knee Replacement; Arthroplasty, Knee; Arthroplasty, Partial Knee; Arthroplasty, Total Knee; Arthroplasty, Unicompartmental Knee; Arthroplasty, Unicondylar Knee; Knee Arthroplasty, Partial; Knee Arthroplasty, Unicompartmental; Knee Arthroplasty, Unicondylar; Knee Replacement, Partial; Knee Replacement, Unicompartmental; Knee Replacement, Unicondylar; Total Knee Arthroplasty; Knee Replacement, Total

Networked: 13446 relevant articles (786 outcomes, 2179 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 34913

Experts

1.	Mont, Michael A: 166 articles (07/2022 - 04/2002)
2.	Parvizi, Javad: 99 articles (12/2022 - 12/2002)
3.	Sodhi, Nipun: 61 articles (07/2022 - 07/2017)
4.	Schwarzkopf, Ran: 57 articles (12/2022 - 12/2011)
5.	Abdel, Matthew P: 54 articles (12/2022 - 11/2011)
6.	Della Valle, Craig J: 45 articles (01/2022 - 09/2002)
7.	Kehlet, Henrik: 45 articles (01/2022 - 08/2007)
8.	Sculco, Peter K: 43 articles (06/2022 - 12/2017)
9.	Higuera, Carlos A: 42 articles (07/2022 - 01/2016)
10.	Hanssen, Arlen D: 41 articles (06/2021 - 06/2002)

Related Diseases

1.	Pain (Aches) 07/01/2023 - "Total knee arthroplasty (TKA) is one of the most commonly performed orthopedic procedures, resulting in pain relief, as well as improved function and QoL. " 01/01/2023 - "Total knee arthroplasty (TKA) is effective for pain reduction in most patients, but 15% or more report unsatisfactory long-term pain outcomes. " 10/18/2022 - "The most effective treatment for knee joint pain is total knee arthroplasty (TKA), but the risk of pain and swelling in patients after surgery is high. " 11/01/2021 - "Although most total knee replacement (TKR) recipients report less pain and improved function after TKR, many remain sedentary. " 05/01/2012 - "The best examples of positive outcome for both pain relief and functional improvement are total hip arthroplasty and total knee arthroplasty. "
2.	Knee Osteoarthritis 01/01/2023 - "Background: Total knee arthroplasty (TKA) is a highly effective treatment for severe knee osteoarthritis that is increasingly performed in younger, more active patients. " 01/01/2022 - "Knee osteoarthritis, one of the most common age-associated diseases, can be effectively treated via total knee arthroplasty (TKA). " 08/01/2021 - "Medial unicompartmental knee arthroplasty (UKA) is considered the most effective treatment for anteromedial knee osteoarthritis. " 11/01/2019 - "Total knee arthroplasty (TKA) has been established as the most effective treatment for end-stage, symptomatic osteoarthritis of the knee. " 01/01/2019 - "Total knee arthroplasty (TKA) is the most common treatment for end-stage knee osteoarthritis and continuous femoral nerve block (CFNB) has become the gold standard for analgesia. "
3.	Osteoarthritis 10/01/2022 - "Total knee arthroplasty (TKA) has been proven to be a highly efficacious procedure for patients with end-stage osteoarthritis who have persistent symptoms not managed by conservative treatment. " 08/01/2018 - "The knee arthroplasty is the best option for patients with advanced osteoarthritis who have failed all other conservative options, but regrettably many patients fail to undergo surgery due to co-morbidities or other reasons. " 01/01/2018 - "Total knee arthroplasty (TKA) is the most common and cost-effective treatment for older adults with long-standing osteoarthritis. " 01/01/2016 - "Total knee arthroplasty (TKA) is the most common and cost-effective treatment for older adults with long-standing osteoarthritis. " 12/01/2016 - "Total knee arthroplasty (TKA) is a proven and cost-effective treatment for osteoarthritis. "
4.	Infections 09/01/2020 - "However, studies investigating the efficacy of VP to prevent infection in primary total knee arthroplasty (TKA) are very rare. " 06/01/2007 - "Associated with medical treatment for the infection we have been able to achieve complete remission of infection in all patients who underwent arthrodesis for an infected knee arthroplasty." 10/01/2003 - "The rate of infection improved very significantly over the last five years both for knee arthroplasty and spinal surgery. " 03/01/1990 - "A prospective, controlled, randomized trial of continuous passive motion and immobilization after knee arthroplasty revealed that continuous passive motion significantly improved early and late flexion of the knee, reduced the duration of stay in the hospital, and did not increase the incidence of superficial infection or problems with wound-healing. " 01/01/2019 - "With application of a treatment protocol for acute infections following total knee arthroplasty, 26 patients (81.2%) had good results and 6 (18.8%) had unsatisfactory results. "
5.	Postoperative Pain 01/01/2017 - "Postoperative pain control is an important factor in determining recovery in total knee arthroplasty (TKA).The aim of the study was to assess the efficacy of 4 sessions of transcranial direct current stimulation (tDCS) over primary motor cortex (M1) in patients undergoing unilateral TKA. " 06/29/2019 - "The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA). " 02/01/2014 - "Local infiltration analgesia is a simple technique that has proven effective in postoperative pain management after total knee arthroplasty. " 02/01/2020 - "Postoperative pain management in the total knee replacement (TKR) represent a fundamental step for a positive outcome, allowing rapid mobilization, already on the first day. " 10/01/2016 - "Local infiltration analgesia (LIA) during total knee arthroplasty has been shown to give statistically significant reduction in post-operative pain. "

Related Drugs and Biologics

1.	Analgesics (Analgesic Drugs)
2.	Tranexamic Acid (AMCA)
3.	Opioid Analgesics (Opioids)
4.	Bupivacaine (Bupivacaine Hydrochloride)
5.	Anti-Bacterial Agents (Antibiotics)
6.	Aspirin (Acetylsalicylic Acid)
7.	Enoxaparin (Lovenox)
8.	Warfarin (Coumadin)
9.	Rivaroxaban
10.	Morphine (MS Contin)

Related Therapies and Procedures

1.	Analgesia
2.	Knee Replacement Arthroplasty (Total Knee Replacement)
3.	Hip Replacement Arthroplasty (Total Hip Replacement)
4.	Arthroplasty
5.	Osteotomy