HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Neurodegenerative Diseases (Neurodegenerative Disease)

Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
Also Known As:
Neurodegenerative Disease; Neurodegenerative Disorders; Degenerative Diseases, Central Nervous System; Degenerative Diseases, Neurologic; Degenerative Diseases, Spinal Cord; Degenerative Neurologic Diseases; Degenerative Neurologic Disorders; Nervous System Degenerative Diseases; Neurologic Degenerative Conditions; Neurologic Degenerative Diseases; Neurologic Diseases, Degenerative; Degenerative Condition, Neurologic; Degenerative Conditions, Neurologic; Degenerative Neurologic Disease; Degenerative Neurologic Disorder; Neurodegenerative Disorder; Neurologic Degenerative Condition; Neurologic Degenerative Disease; Neurologic Disease, Degenerative; Neurologic Disorder, Degenerative; Neurologic Disorders, Degenerative; Degenerative Diseases, Nervous System
Networked: 42472 relevant articles (1514 outcomes, 3499 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Alzheimer Disease (Alzheimer's Disease)
2. Neoplasms (Cancer)
3. Parkinson Disease (Parkinson's Disease)
4. Inflammation (Inflammations)
5. Cardiovascular Diseases (Cardiovascular Disease)

Experts

1. Trojanowski, John Q: 115 articles (06/2022 - 05/2002)
2. Zetterberg, Henrik: 100 articles (10/2022 - 01/2005)
3. Masliah, Eliezer: 98 articles (01/2022 - 02/2001)
4. Blennow, Kaj: 90 articles (10/2022 - 01/2002)
5. Lee, Virginia M-Y: 82 articles (01/2022 - 05/2002)
6. Dobson, Christopher M: 75 articles (02/2022 - 07/2005)
7. Youdim, Moussa B H: 62 articles (11/2018 - 01/2002)
8. Rubinsztein, David C: 61 articles (01/2022 - 05/2002)
9. Perry, George: 60 articles (10/2021 - 01/2002)
10. Mattson, Mark P: 58 articles (01/2021 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neurodegenerative Diseases:
1. Proteins (Proteins, Gene)FDA Link
2. AntioxidantsIBA
3. Biomarkers (Surrogate Marker)IBA
01/01/2006 - "In the future, neuroimaging techniques may shed the most light on the pathophysiology of HD by defining neurodegenerative disease phenotypes as a valuable tool for knowing when patients become "symptomatic," having been in a gene-positive presymptomatic state, and as a biomarker in following the disease, thereby providing a prospect for improved patient care."
05/10/2011 - "Biomarker development is important to the therapeutic imperative for neurodegenerative diseases, as biomarkers hold transformative promise for the design and conduct of clinical trials and, ultimately, for medical management of these diseases. "
04/01/2023 - "Saliva can be obtained easily, and salivary biomarkers have been proven effective in detecting neurodegenerative diseases. "
01/01/2020 - "The use of high spatial resolution magnetic resonance imaging and the improvement in data preprocessing methods have enabled the study of structural volume changes on a wide range of disorders, particularly in neurodegenerative diseases where different brain morphometry analyses are being broadly used in an effort to improve diagnostic biomarkers. "
11/06/1998 - "Knowledge of etiology and pathogenesis, improved design of clinical trials, the development of biological markers, the advent of genetic animal models, the enhanced identification of susceptibility factors, and more effective drug delivery-such advances have improved the prospects for forestalling onset of illness and clinical decline in the growing numbers of people affected by neurodegenerative disorders."
4. Neuroprotective AgentsIBA
5. PolyphenolsIBA
6. Amyloid (Amyloid Fibrils)IBA
7. Protein AggregatesIBA
8. EnzymesIBA
9. MelatoninIBA
10. Nerve Growth Factors (Neurotrophins)IBA

Therapies and Procedures

1. Therapeutics
2. Transplantation
3. Cell- and Tissue-Based Therapy (Cell Therapy)
4. Drug Therapy (Chemotherapy)
5. Immunotherapy