Calcium Citrate

A colorless crystalline or white powdery organic, tricarboxylic acid occurring in plants, especially citrus fruits, and used as a flavoring agent, as an antioxidant in foods, and as a sequestrating agent. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

Also Known As:

Networked: 83 relevant articles (3 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kirejczyk, Jan K: 2 articles (05/2015 - 09/2014)
2.	Porowski, Tadeusz: 2 articles (05/2015 - 09/2014)
3.	Wasilewska, Anna: 2 articles (05/2015 - 09/2014)
4.	Arrabal-Polo, Miguel Angel: 2 articles (04/2013 - 01/2012)
5.	Poyatos-Andujar, Antonio: 2 articles (04/2013 - 01/2012)
6.	Arrabal-Martin, Miguel: 2 articles (04/2013 - 01/2012)
7.	Zuluaga-Gomez, Armando: 2 articles (04/2013 - 01/2012)
8.	Boggia, José: 2 articles (10/2012 - 04/2004)
9.	Gadola, Liliana: 2 articles (10/2012 - 04/2004)
10.	Konjevoda, P: 2 articles (06/2004 - 05/2000)

Related Diseases

1.	Renal Insufficiency (Renal Failure) 01/01/1993 - "We therefore measured serum and urinary aluminum before and following calcium citrate therapy in patients with moderate renal failure and in normal subjects maintained on constant metabolic diets with known aluminum content (967-1034 mumol/day, or 26.1-27.9 mg/day, in patients and either 834 or 1579 mumol/day, or 22.5 and 42.6 mg/day, in normal subjects). " 01/01/1993 - "Seven patients with moderate renal failure (endogenous creatinine clearance of 43 ml/min) took 50 mmol (2 g) calcium/day as effervescent calcium citrate with meals for 17 days. " 06/01/1991 - "Thus, calcium citrate markedly enhances the absorption of aluminum from aluminum hydroxide and the two must not be prescribed together in patients with renal failure." 05/01/2011 - "However, calcium citrate, which is also used for supplementation purposes, has not been studied previously and calcium acetate, which is used to treat hyperphosphatemia in renal failure, has been reported to show little or no interference with levothyroxine absorption in a retrospective pharmacoepidemiologic study. "
2.	Acidosis 10/01/2012 - "Calcium citrate decreased acidosis induced EMT and improved cells performance, without reduction of TGF-β production. " 04/01/2004 - "The aim of this study was to evaluate the effects of correction of metabolic acidosis with calcium citrate in an experimental model of renal mass ablation. " 10/01/2012 - "At 80% confluence, after 24 hr under serum free conditions, cells were distributed in three groups (24 hours): A) Control: pH 7.4, B) Acidosis: pH 7.0 and C) Calcium citrate (0.2 mmol/L) + pH 7.0. " 10/01/2012 - "Calcium citrate improves the epithelial-to-mesenchymal transition induced by acidosis in proximal tubular cells."
3.	Kidney Calculi (Kidney Stone) 08/01/1994 - "Limited risk of kidney stone formation during long-term calcium citrate supplementation in nonstone forming subjects." 01/01/2011 - "Calcium citrate formulations taken between meals may help to prevent abdominal distension and flatulence, as well as minimize the risk of renal calculus formation, thus helping to optimize patient compliance. " 04/01/2008 - "Using cadaveric specimens, we placed bra wires, gallbladder clips, a large gallstone, a calcium carbonate or a calcium citrate pill lateral to L1, or a large or small calcium-containing kidney stone lateral to L3 and compared the mean bone mineral density (BMD) of individual vertebral bodies and L1-L4 with and without the soft tissue artifact. " 01/01/2012 - "We tested associations between age, weight and intra-individual variation in urinary calcium, citrate, chloride, creatinine, potassium, magnesium, sodium, ammonium, oxalate, phosphorus, sulfate, uric acid and urea nitrogen in 9,024 male and 6,758 female kidney stone patients. "
4.	Flatulence 01/01/2011 - "Calcium citrate formulations taken between meals may help to prevent abdominal distension and flatulence, as well as minimize the risk of renal calculus formation, thus helping to optimize patient compliance. "
5.	Osteoporosis 06/24/2015 - "Absorption and Bioavailability of Nano-Size Reduced Calcium Citrate Fortified Milk Powder in Ovariectomized and Ovariectomized-Osteoporosis Rats." 01/01/2011 - "Therefore, calcium citrate combined with vitamin D is the combination of choice for the prevention or treatment of osteoporosis." 01/01/2011 - "Calcium citrate and vitamin D in the treatment of osteoporosis." 10/01/1994 - "Effect of calcium citrate supplementation on urinary calcium oxalate saturation in female stone formers: implications for prevention of osteoporosis." 03/01/1991 - "Transiliac crest bone biopsies were obtained from 16 patients with osteoporosis and vertebral compression fractures (12 women and 4 men, mean age 56 years) before and after approximately 2 years of intermittent slow-release sodium fluoride therapy (25 mg twice a day) combined with continuous calcium citrate supplementation. "

Related Drugs and Biologics

1.	Calcium
2.	Creatinine
3.	Calcium Carbonate (Limestone)
4.	Citric Acid (Citrate)
5.	Uric Acid (Urate)
6.	Magnesium
7.	Potassium
8.	Phosphorus
9.	Potassium Citrate
10.	Sodium

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Bariatric Surgery
3.	Blood Component Removal (Apheresis)