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Type A Botulinum Toxins (Botulinum A Toxin)

Subscribe to New Research on Type A Botulinum Toxins

A serotype of botulinum toxins that has specificity for cleavage of SYNAPTOSOMAL-ASSOCIATED PROTEIN 25.

Also Known As:

Botulinum A Toxin; Botulinum Toxins, Type A; Botulinum Neurotoxin A; Clostridium Botulinum Toxin Type A; Clostridium botulinum A Toxin; Oculinum; Neurotoxin A, Botulinum; Toxin, Botulinum A; Botulinum Toxin Type A

Networked: 1606 relevant articles (264 outcomes, 306 trials/studies)

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Drug Context: Research Results

Experts

1.	Santamato, Andrea: 19 articles (08/2015 - 04/2008)
2.	Ranieri, Maurizio: 16 articles (08/2015 - 04/2008)
3.	Panza, Francesco: 16 articles (08/2015 - 04/2008)
4.	Fiore, Pietro: 15 articles (08/2015 - 04/2008)
5.	Kuo, Hann-Chorng: 11 articles (01/2013 - 03/2003)
6.	Melo, Ailton: 10 articles (10/2014 - 03/2005)
7.	Koman, L Andrew: 10 articles (03/2013 - 01/2002)
8.	Park, Eun Sook: 9 articles (01/2015 - 11/2002)
9.	Frisardi, Vincenza: 9 articles (03/2013 - 11/2008)
10.	Picelli, Alessandro: 8 articles (08/2015 - 05/2012)

Related Diseases

1.	Pain (Aches) 07/01/2007 - "The patients treated with botulinum toxin type A showed a significantly greater pain improvement from the first week post-infiltration. " 01/01/2002 - "Botulinum toxin type A is effective in the reduction of muscle tenderness and pain in many diseases associated with myofascial pain. " 06/01/2011 - "This randomised controlled crossover trial examined the efficacy of botulinum toxin type A (BoNT-A) injection, plus an exercise programme, to remediate chronic anterior knee pain (AKP) associated with quadriceps muscle imbalance. " 01/01/2012 - "Enduring efficacy of Botulinum toxin type A injection for refractory anterior knee pain." 09/01/2011 - "Comment on: Efficacy of botulinum toxin type A for treatment of persistent myofascial TMD pain: a randomized, controlled, double-blind multicenter study, by Ernberg, Hedenberg-Magnusson, List, and Svensson."
2.	Hyperhidrosis 01/01/2009 - "Botulinum Toxin type A (BTX-A) has revolutionized the treatment of focal hyperhidrosis (HH) in recent years and has dramatically reduced the invasive surgical techniques that have been performed in the past to control severe focal HH unresponsive to topical therapies. " 08/01/2002 - "Botulinum toxin type A (BTX-A) has been shown to be highly effective in reducing palmar hyperhidrosis. " 12/01/2004 - "Clinical trials investigating botulinum toxin type A use in axillary and palmar hyperhidrosis show significant benefits with few side-effects reported, with a favourable impact also being seen on patient quality of life. " 01/01/2008 - "As a result, there is a strong evidence to support the efficacy of botulinum toxin type A in axillary (Level A evidence) and palmar (Level B evidence) hyperhidrosis." 09/15/2001 - "Botulinum toxin type A is a safe and effective treatment for primary axillary hyperhidrosis and produces high levels of patient satisfaction."
3.	Stroke (Strokes) 04/01/2010 - "Background Focal spasticity is a significant motor disorder following stroke, and Botulinum Toxin Type-A (BoNT-A) is a useful treatment for this. " 06/01/2012 - "Botulinum toxin type A (BoNT-A) has been reported to be an effective treatment for limb spasticity after stroke. " 07/01/2005 - "In conclusion, botulinum toxin type A is a cost-effective treatment for post-stroke spasticity." 01/01/2015 - "In this case report, we describe the type and duration of a physical therapy and botulinum toxin type A (BoNTA) intervention directed at lower limb spasticity and the gait and balance improvement in a patient post-stroke. " 12/15/2014 - "Our aim was to compare the reduction of spasticity and the related finger position at rest improvement in post-stroke patients treated with botulinum toxin type A in upper limb muscles using ultrasound guidance and manual needle placement. "
4.	Cerebral Palsy (Spastic Diplegia) 07/01/2000 - "Beneficial effects persisted for 10 to 12 mo in most patients, with three patients exhibiting benefits for at least 20 mo. The results of the present study indicate that a very low dose of botulinum toxin type A combined with'rehabilitation therapy resulted in a long-lasting decrease in spasticity and an improvement in gait in children with cerebral palsy." 10/01/2003 - "In conclusion, intramuscular botulinum toxin type A administration may be effective in children with cerebral palsy, especially at week 4 and when injected in gastrocnemius." 12/01/2006 - "Botulinum toxin type A can be both safe and effective in relieving spasticity in pediatric patients with cerebral palsy. " 01/01/2001 - "Botulinum toxin type A is well tolerated, safe, and effective in the treatment of patients with spastic cerebral palsy. " 04/01/2013 - "Previous studies have shown the efficacy of botulinum toxin type A (BoNT-A) in the management of ambulant individuals with cerebral palsy (CP). "
5.	Migraine Disorders (Migraine) 02/01/2004 - "Numerous retrospective open-label chart reviews and 4 double-blind, placebo-controlled studies have demonstrated that botulinum toxin type A is significantly effective in migraine prophylaxis and reduces the frequency, severity, and disability associated with migraine headaches. " 09/01/2004 - "Recent studies suggest botulinum toxin type A is effective in preventing migraine. " 05/01/2002 - "An open-label study and 2 double-blind, placebo-controlled studies have provided supporting evidence of botulinum toxin type A (BTX-A) as an effective, well-tolerated treatment for migraine. " 06/01/2001 - "An open-label study and 2 double-blind, placebo-controlled studies have provided supporting evidence of botulinum toxin type A (BTX-A) as an effective, well-tolerated treatment for migraine. " 11/01/2013 - "Botulinum toxin type A (BoNT-A) has been reported as an effective treatment for chronic migraine. "

Related Drugs and Biologics

1.	onabotulinumtoxinA (Botox)
2.	abobotulinumtoxinA
3.	Botulinum Toxins (Botulinum Toxin)
4.	Cosmetics
5.	Acetylcholine (Acetylcholine Chloride)
6.	Ice
7.	Baclofen
8.	Adrenal Cortex Hormones (Corticosteroids)
9.	tizanidine (Zanaflex)
10.	Cholinergic Antagonists (Anticholinergics)

Related Therapies and Procedures

1.	Injections
2.	Intramuscular Injections
3.	Aftercare (After-Treatment)
4.	Intradermal Injections
5.	Curettage