Facies

The appearance of the face that is often characteristic of a disease or pathological condition, as the elfin facies of WILLIAMS SYNDROME or the mongoloid facies of DOWN SYNDROME. (Random House Unabridged Dictionary, 2d ed)

Networked: 384 relevant articles (1 outcomes, 9 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hirsutism
2.	Hypertension (High Blood Pressure)
3.	Cleft Palate (Palate, Cleft)
4.	Congenital Abnormalities (Deformity)
5.	Hypocalcemia

Experts

1.	Robertson, Stephen P: 3 articles (03/2013 - 05/2007)
2.	Rosenbloom, Arlan L: 3 articles (01/2009 - 08/2007)
3.	Hadchouel, Michelle: 3 articles (11/2007 - 09/2002)
4.	Rezaei, Nima: 2 articles (10/2015 - 12/2003)
5.	Hughes, Richard A C: 2 articles (01/2015 - 01/2012)
6.	Mehndiratta, Man Mohan: 2 articles (01/2015 - 01/2012)
7.	Stark, Zornitza: 2 articles (06/2014 - 09/2010)
8.	Cong, Qian: 2 articles (01/2014 - 01/2014)
9.	Grishin, Nick V: 2 articles (01/2014 - 01/2014)
10.	Al Kaissi, Ali: 2 articles (05/2013 - 07/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Facies:

1.	Tacrolimus (Prograf)FDA LinkGeneric 01/01/2001 - "Additional benefits of conversion to tacrolimus include improvement in growth and resolution of hypertension, hirsutism and cushingoid facies. " 01/01/2011 - "We report a case of chronic actinic dermatitis presenting with leonine facies and secondary adrenal insufficiency, which was successfully treated with topical tacrolimus. " 01/01/2011 - "Chronic actinic dermatitis with leonine facies and iatrogenic adrenal insufficiency successfully treated with topical tacrolimus."
2.	DNA (Deoxyribonucleic Acid)IBA 01/01/2014 - "Comparative analyses of DNA barcodes, genitalia, and facies suggest that Heraclidesoviedo (Gundlach, 1866), reinstated status, is a species-level taxon rather than a subspecies of Heraclidesthoas (Linnaeus, 1771); and Heraclidespallas (G. " 01/01/2014 - "However, facies, genitalia and 2.1% different DNA barcodes set Hermeuptychia populations in the lower Rio Grande Valley of Texas apart from H. " 01/01/2011 - "Deficiencies in DNA ligase 4 and the recently described Cernunnos gene result in microcephaly, growth retardation, and typical bird-like facies. " 12/01/1995 - "To study the usefulness of fluorescent in situ hybridization (FISH) with the DNA probe D22S75 for detecting microdeletions in chromosome 22q11.2 in metaphases from patients with features of "CATCH 22" (cardiac anomalies, abnormal facies, thymic hypoplasia or aplasia, cleft palate, and hypocalcemia). " 10/01/2014 - "Archaeal metabolism was studied in aragonitic and gypsum facies of the Dead Sea subsurface using high-throughput DNA sequencing. "
3.	CalciumIBA 11/01/1973 - "Familial 'hypercalcaemia' facies with other unusual features and normal serum calcium in two brothers." 04/11/1985 - "Hypercalcemia in the three children with elfin facies was controlled by a low-calcium diet. " 01/03/2002 - "She presented signs of Albright osteodystrophy (short stature, round facies, obesity, short neck, brachydactylia), hypocalcemia (ionized calcium of 1.08 mmol/l and total calcium of 6.7 mg/dl) hyperphosphatemia (9.4 mg/dl), elevated serum PTH levels (223.0 pg/ml), osteoporosis, and hypergonadotrophic hypogonadism (7.0 mU/ml LH, 9.3 mU/ml FSH and undetectable estradiol levels)." 09/01/2008 - "The study finds, from hierarchical cluster analysis that there are two main hydrochemical facies namely the calcium-sodium-chloride-bicarbonate waters and the magnesium-potassium-sulfate-nitrate waters in the northern and southern sections, respectively, of the Afram Plains area. " 12/01/2008 - "Component 2 represents sulfated and chlorinated calcium and sodium groundwaters; Component 3 represents sodium bicarbonated groundwaters; and Component 4 is characterized by sodium sulfated with high fluoride facies. "
4.	AlkaliesIBA 08/01/2014 - "The abundances of Ca(2+) and Mg(2+) over alkalis infer mixed type of groundwater facies and reverse exchange reactions. " 05/01/2012 - "The groundwater of the study area is characterized by the dominance of alkaline earth (Ca(2+), Mg(2+)) and strong acids (Cl(-), SO(4)(-)) over alkalies (Na(+), K(+)) and weak acids (HCO(3)(-), CO(3)(-)) during both post-monsoon and pre-monsoon seasons of the year 2010, based on the hydrochemical facies. " 12/01/2010 - "The hydrogeochemical facies indicate alkalis (Na and K) exceed alkaline earths (Ca and Mg) and strong acids (Cl and SO(4)) exceed weak acid (HCO(3)). " 03/01/2003 - "It appears that, in contrast to the old ferricrete facies, the current ferruginous accumulations are enriched in transitional trace elements (V, Cr, Co, Y, Sc) and Pb, while alkali-earth elements are less differentiated. "
5.	EVAC protocol (CAVE)IBA 07/01/2010 - "Stratigraphic study of the Cova del Gegant's sedimentary fill revealed different cycles of accumulation of typical interior cave and delta facies. " 09/01/2010 - "The depositional sequence of the cave, predating Marine Isotopic Stage 11 (MIS 11) and continuing to present, is in the form of isolated sediment exposures with different depositional facies and vertical and lateral variations. " 08/01/1997 - "This is typical of interior cave facies, and caused by cycles of cut and fill. "
6.	Heavy MetalsIBA 05/01/2013 - "Background concentrations of heavy metals were assessed from uncontaminated sediments (soils) in the study area that belong to the same sedimentary facies and were not affected by reductimorphic processes. " 12/01/2004 - "The analysis of water and sediments of the surrounding superficial aquatic ecosystems shows a modification of water chemical facies and an enrichment in heavy metals, mainly under the solid phase for Fe, Pb, Cu, Co, Cr and Ni, and under dissolved fraction for Cd and Zn. "
7.	UraniumIBA 11/01/2011 - "Finally, facies-based porosity and reactive surface area variations were shown to affect aqueous uranium concentration distributions with localized effects of the fine lithofacies having the largest impact on U(VI) surface complexation. " 12/07/2000 - "Here we investigate this hypothesis, using uranium-thorium dating of the Hulopoe gravel (on Lana'i) and a study of stratigraphic relationships, such as facies changes and hiatuses, within the deposit. "
8.	SoilIBA 09/01/2005 - "Microbial communities of alluvial soils in the facies on islands in the Selenga estuary and near Stepnoi Dvorets and Istomino Settlements were studied. " 05/01/2013 - "Background concentrations of heavy metals were assessed from uncontaminated sediments (soils) in the study area that belong to the same sedimentary facies and were not affected by reductimorphic processes. "
9.	Radioisotopes (Radionuclides)IBA 01/01/2001 - "In this report, multivariate analysis methods have been employed to study the relationships between the activities of the radionuclides and some sedimentological variables like granulometric facies, organic content and apparent density. " 03/01/2009 - "Furthermore, the proposal model for granulometric facies as a function of activity concentrations of the abovementioned radionuclides provides for the sediments distribution a representation which agrees with the values of the tidal energy distribution obtained using numeric models calibrated with experimental data from current meters and water level recorders."
10.	AcidsIBA 05/01/2012 - "The groundwater of the study area is characterized by the dominance of alkaline earth (Ca(2+), Mg(2+)) and strong acids (Cl(-), SO(4)(-)) over alkalies (Na(+), K(+)) and weak acids (HCO(3)(-), CO(3)(-)) during both post-monsoon and pre-monsoon seasons of the year 2010, based on the hydrochemical facies. " 12/01/2010 - "The hydrogeochemical facies indicate alkalis (Na and K) exceed alkaline earths (Ca and Mg) and strong acids (Cl and SO(4)) exceed weak acid (HCO(3)). "

Therapies and Procedures

1.	Sutures (Suture) 01/01/1986 - "It is suggested that this deeply located cartilage joint is the primary site of pathogenesis in the craniostenotic facies and not the coronal sutures which are operated upon. " 04/01/2001 - "Additional findings included an abnormal facies with a distinctive small, round and open mouth, low set ears, small nose, widely spaced sutures, flexion contractures of the extremities, and poorly expanded lungs. " 04/01/1988 - "Optic hypoplasia occurred in six cases, large anterior and posterior fontanelles in four, wide sutures in four, depressed nasal bridge in three, facial palsy in three, and one infant had an asymmetrical, crying facies. " 01/01/1986 - "The Crouzon facies, including midfacial hypoplasia and exorbitism, have been linked to the premature synostosis of calvarial sutures. " 01/01/1983 - "Craniofacial dysmorphism includes brachymicrocephaly, a round and flat facies, a high forehead with a prominent metopic suture, thin and scarse hair, palpebral fissures slanted upward, hypertelorism and epicanthal folds, a bulbous nose with a flattened nose-bridge, a large and prominent philtrum, well-defined Cupid's bow, and retrognathia. "
2.	Adenoidectomy 10/01/1997 - "Surgery is also sometimes recommended as a method to influence facial growth as in tonsillectomy and adenoidectomy for 'adenoid facies syndrome.' There are a number of different theories concerning the factors that influence the growth of the face and cranium. " 11/01/2012 - "Obstructive mouth breathing due to adenoids in growing children can cause alteration in craniofacial morphology leading to adenoid facies, adenoidectomy procedure helps in alleviating the obstruction and facilitates the normal growth of craniofacial complex." 01/01/2009 - "Other common adverse effects involve hyperplasia of lymphoid tissue, which may require tonsillectomy/adenoidectomy, accumulation of body fat, and coarsening of facies. "
3.	Transplants (Transplant) 01/01/1965 - "[Correction of facies scaphoidea and restoration of the basis nasi in leprosy by means of naso-genal dermal-fat grafts]." 03/01/1985 - "Results are as follows: a) Children with vitamin D intoxication (n = 2) had elevated serum 25-(OH)D and 24,25-(OH)2D concentrations but their 1,25-(OH)2D concentrations were similar to those found in normocalcemic children (10-110 pg/ml); b) Children with familial idiopathic hypercalcemia and hypocalciuria (n = 5), children with hypercalcemia and either Bartter's syndrome (n = 1), hemangiomatosis (n = 1), osteopetrosis after medullary graft (n = 1), also had 1,25-(OH)2D concentrations in the normal range; c) In contrast, 1,25-(OH)2D were elevated (160-470 pg/ml) in the four children with severe idiopathic hypercalcemia and elfin facies."
4.	Bone Marrow Transplantation (Transplantation, Bone Marrow) 12/01/2003 - " emphasize the need for early diagnosis on basis of characteristic facies and diagnostic laboratory examinations and early bone marrow transplantation (BMT) in patients." 07/01/1998 - "There was a beneficial effect of bone marrow transplantation on visceral features (hepatosplenomegaly, obstruction of the upper airway, and coarse facies); however, dysostosis multiplex worsened. "
5.	Tonsillectomy 10/01/1997 - "Surgery is also sometimes recommended as a method to influence facial growth as in tonsillectomy and adenoidectomy for 'adenoid facies syndrome.' There are a number of different theories concerning the factors that influence the growth of the face and cranium. " 01/01/2009 - "Other common adverse effects involve hyperplasia of lymphoid tissue, which may require tonsillectomy/adenoidectomy, accumulation of body fat, and coarsening of facies. "