Muscle Neoplasms (Neoplasms, Muscle)

Tumors or cancer located in muscle tissue or specific muscles. They are differentiated from NEOPLASMS, MUSCLE TISSUE which are neoplasms composed of skeletal, cardiac, or smooth muscle tissue, such as MYOSARCOMA or LEIOMYOMA.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Alveolar Rhabdomyosarcoma
2.	Sepsis (Septicemia)
3.	Embryonal Rhabdomyosarcoma
4.	Starvation
5.	Myositis (Idiopathic Inflammatory Myopathies)

Experts

1.	Keller, Charles: 2 articles (08/2014 - 04/2011)
2.	Svalina, Matthew N: 1 article (08/2014)
3.	Patterson, Cam: 1 article (09/2013)
4.	DeKroon, Robert M: 1 article (09/2013)
5.	Hamlett, Eric D: 1 article (09/2013)
6.	Alzate, Oscar: 1 article (09/2013)
7.	Schisler, Jonathan C: 1 article (09/2013)
8.	Gautel, Mathias: 1 article (09/2013)
9.	Rubel, Carrie E: 1 article (09/2013)
10.	Nelon, Laura D: 1 article (04/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Muscle Neoplasms:

1.	Insulin (Novolin)FDA Link 04/01/2011 - "Inhibition of the insulin-like growth factor 1 receptor (Igf1r) is an approach being taken in clinical trials to overcome the dismal outcome for metastatic alveolar rhabdomyosarcoma (ARMS), an aggressive muscle cancer of children and young adults. "
2.	Proteasome Endopeptidase Complex (Proteasome)IBA 09/01/2013 - "The ubiquitin-proteasome system (UPS) plays a central role in maintaining protein homeostasis, emphasized by a myriad of diseases that are associated with altered UPS function such as cancer, muscle-wasting, and neurodegeneration. "
3.	UbiquitinIBA 09/01/2013 - "The ubiquitin-proteasome system (UPS) plays a central role in maintaining protein homeostasis, emphasized by a myriad of diseases that are associated with altered UPS function such as cancer, muscle-wasting, and neurodegeneration. "
4.	Lovastatin (Mevacor)FDA LinkGeneric 12/01/2001 - "Chronic long-term treatment with lovastatin was well tolerated, with no treatment group differences in the frequency of cancer, muscle symptoms, and clinically important liver enzyme elevations. "
5.	GlucocorticoidsIBA 01/01/1997 - "The signals activating this pathway include metabolic acidosis and glucocorticoids but must be more diverse since the pathway is also activated in response to starvation, sepsis, cancer, muscle denervation, thermal injury, and acute diabetes. "
6.	tebufenozide (Mimic)IBA 06/01/2009 - "MR imaging findings of focal myositis: a pseudotumour that may mimic muscle neoplasm."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 08/11/2014 - "Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. "
2.	Denervation 01/01/1997 - "The signals activating this pathway include metabolic acidosis and glucocorticoids but must be more diverse since the pathway is also activated in response to starvation, sepsis, cancer, muscle denervation, thermal injury, and acute diabetes. "